| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the 5211181-950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADM | adrenomedullin |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALPK1 | alpha-kinase 1 |
| ANKRD26 | ankyrin repeat domain 26 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARTN | artemin |
| ATG3 | autophagy related 3 |
| BAX | BCL2-associated X protein |
| BIN1 | bridging integrator 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CDK3 | cyclin-dependent kinase 3 |
| CLDN15 | claudin 15 |
| CPNE7 | copine VII |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DESI2 | desumoylating isopeptidase 2 |
| DLX4 | distal-less homeobox 4 |
| DVL2 | dishevelled segment polarity protein 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| GLRX | glutaredoxin (thioltransferase) |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1107 | KIAA1107 |
| KLHL24 | kelch-like family member 24 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LPA | lipoprotein, Lp(a) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAGEA3 | melanoma antigen family A3 |
| MAP1B | microtubule-associated protein 1B |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MINK1 | misshapen-like kinase 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFRKB | nuclear factor related to kappaB binding protein |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRF1 | nuclear respiratory factor 1 |
| PAPOLA | poly(A) polymerase alpha |
| PDCD2 | programmed cell death 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE9A | phosphodiesterase 9A |
| PEX16 | peroxisomal biogenesis factor 16 |
| PEX7 | peroxisomal biogenesis factor 7 |
| PHF1 | PHD finger protein 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G3 | phospholipase A2, group III |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POLH | polymerase (DNA directed), eta |
| PORCN | porcupine homolog (Drosophila) |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| RECQL5 | RecQ protein-like 5 |
| RRAGD | Ras-related GTP binding D |
| SAP30 | Sin3A-associated protein, 30kDa |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SP100 | SP100 nuclear antigen |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STK16 | serine/threonine kinase 16 |
| TDRD3 | tudor domain containing 3 |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM53 | transmembrane protein 53 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XK | X-linked Kx blood group |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 |
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ARMC6 | armadillo repeat containing 6 |
| AXIN1 | axin 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CA11 | carbonic anhydrase XI |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHST10 | carbohydrate sulfotransferase 10 |
| CISH | cytokine inducible SH2-containing protein |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSK | cathepsin K |
| CUEDC1 | CUE domain containing 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| DNAL4 | dynein, axonemal, light chain 4 |
| DUSP8 | dual specificity phosphatase 8 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| ELMO3 | engulfment and cell motility 3 |
| EPPK1 | epiplakin 1 |
| FAM179B | family with sequence similarity 179, member B |
| FBRS | fibrosin |
| FOXC1 | forkhead box C1 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GALT | galactose-1-phosphate uridylyltransferase |
| GPN2 | GPN-loop GTPase 2 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HDAC4 | histone deacetylase 4 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IRF6 | interferon regulatory factor 6 |
| KAT2B | K(lysine) acetyltransferase 2B |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0125 | KIAA0125 |
| KIAA0355 | KIAA0355 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| METTL2B | methyltransferase like 2B |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MSX1 | msh homeobox 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO19 | myosin XIX |
| NAV2 | neuron navigator 2 |
| NBEAL2 | neurobeachin-like 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTGES2 | prostaglandin E synthase 2 |
| RAB5B | RAB5B, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBBP5 | retinoblastoma binding protein 5 |
| RBL1 | retinoblastoma-like 1 |
| RBM28 | RNA binding motif protein 28 |
| RECQL4 | RecQ protein-like 4 |
| RGS19 | regulator of G-protein signaling 19 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| THOP1 | thimet oligopeptidase 1 |
| TMEM110 | transmembrane protein 110 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM66 | tripartite motif containing 66 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA3D | tubulin, alpha 3d |
| WDR13 | WD repeat domain 13 |
| WDR91 | WD repeat domain 91 |
| ZNF226 | zinc finger protein 226 |
| ZNF324 | zinc finger protein 324 |
| ZNF552 | zinc finger protein 552 |