| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the 5252917-828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AFF1 | AF4/FMR2 family, member 1 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| BMP2K | BMP2 inducible kinase |
| BTBD7 | BTB (POZ) domain containing 7 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN1 | claudin 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| CPNE7 | copine VII |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DPYS | dihydropyrimidinase |
| DRD1 | dopamine receptor D1 |
| DUSP1 | dual specificity phosphatase 1 |
| EFS | embryonal Fyn-associated substrate |
| EIF4A1 | eukaryotic translation initiation factor 4A1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM110B | family with sequence similarity 110, member B |
| FYB | FYN binding protein |
| GM2A | GM2 ganglioside activator |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM4 | glutamate receptor, metabotropic 4 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HDAC7 | histone deacetylase 7 |
| HFE | hemochromatosis |
| HIST1H1D | histone cluster 1, H1d |
| HOXA6 | homeobox A6 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IDS | iduronate 2-sulfatase |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IL15RA | interleukin 15 receptor, alpha |
| IPO9 | importin 9 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KRT20 | keratin 20, type I |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC40 | leucine rich repeat containing 40 |
| LTC4S | leukotriene C4 synthase |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MIIP | migration and invasion inhibitory protein |
| MSR1 | macrophage scavenger receptor 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEBL | nebulette |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NRG1 | neuregulin 1 |
| OGFR | opioid growth factor receptor |
| OVOL1 | ovo-like zinc finger 1 |
| PAX8 | paired box 8 |
| PDAP1 | PDGFA associated protein 1 |
| PLAT | plasminogen activator, tissue |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POU6F2 | POU class 6 homeobox 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RAD51B | RAD51 paralog B |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF24 | ring finger protein 24 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFRP5 | secreted frizzled-related protein 5 |
| SH2D4A | SH2 domain containing 4A |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SP110 | SP110 nuclear body protein |
| SYK | spleen tyrosine kinase |
| SYNJ2 | synaptojanin 2 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM120B | transmembrane protein 120B |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRIM5 | tripartite motif containing 5 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF639 | zinc finger protein 639 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD14A | abhydrolase domain containing 14A |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ARRB2 | arrestin, beta 2 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDK20 | cyclin-dependent kinase 20 |
| CLK4 | CDC-like kinase 4 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EFHD2 | EF-hand domain family, member D2 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FA2H | fatty acid 2-hydroxylase |
| FBXO22 | F-box protein 22 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FMO4 | flavin containing monooxygenase 4 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FXN | frataxin |
| GLTP | glycolipid transfer protein |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H3H | histone cluster 1, H3h |
| HOXC10 | homeobox C10 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IREB2 | iron-responsive element binding protein 2 |
| IRF7 | interferon regulatory factor 7 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MFAP2 | microfibrillar-associated protein 2 |
| MIR22HG | MIR22 host gene |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NABP2 | nucleic acid binding protein 2 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PMP22 | peripheral myelin protein 22 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB33B | RAB33B, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RNF170 | ring finger protein 170 |
| RNF2 | ring finger protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| S100A4 | S100 calcium binding protein A4 |
| SAV1 | salvador family WW domain containing protein 1 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMAD5 | SMAD family member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNX16 | sorting nexin 16 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNJ2BP | synaptojanin 2 binding protein |
| TCTN1 | tectonic family member 1 |
| TEFM | transcription elongation factor, mitochondrial |
| TMEM260 | transmembrane protein 260 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TSPAN15 | tetraspanin 15 |
| TSPAN5 | tetraspanin 5 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH1 | vasohibin 1 |
| WDR4 | WD repeat domain 4 |
| WRAP73 | WD repeat containing, antisense to TP73 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF14 | zinc finger protein 14 |
| ZNF268 | zinc finger protein 268 |
| ZNF408 | zinc finger protein 408 |
| ZNF443 | zinc finger protein 443 |
| ZNF552 | zinc finger protein 552 |
| ZNF562 | zinc finger protein 562 |
| ZNF668 | zinc finger protein 668 |
| ZNF672 | zinc finger protein 672 |
| ZNF778 | zinc finger protein 778 |
| ZNF85 | zinc finger protein 85 |