5252917-828 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 5252917-828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAM8 ADAM metallopeptidase domain 8
AFF1 AF4/FMR2 family, member 1
ANKMY1 ankyrin repeat and MYND domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
APOLD1 apolipoprotein L domain containing 1
BMP2K BMP2 inducible kinase
BTBD7 BTB (POZ) domain containing 7
C7ORF26 chromosome 7 open reading frame 26
C8ORF4 chromosome 8 open reading frame 4
CCL2 chemokine (C-C motif) ligand 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CLDN1 claudin 1
COL6A1 collagen, type VI, alpha 1
COMP cartilage oligomeric matrix protein
CPNE7 copine VII
CRIP1 cysteine-rich protein 1 (intestinal)
CRTC1 CREB regulated transcription coactivator 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DPYS dihydropyrimidinase
DRD1 dopamine receptor D1
DUSP1 dual specificity phosphatase 1
EFS embryonal Fyn-associated substrate
EIF4A1 eukaryotic translation initiation factor 4A1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM110B family with sequence similarity 110, member B
FYB FYN binding protein
GM2A GM2 ganglioside activator
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRM4 glutamate receptor, metabotropic 4
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC7 histone deacetylase 7
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HOXA6 homeobox A6
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDS iduronate 2-sulfatase
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL15RA interleukin 15 receptor, alpha
IPO9 importin 9
ITFG2 integrin alpha FG-GAP repeat containing 2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KRT20 keratin 20, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC257152 uncharacterized LOC257152
LPAR4 lysophosphatidic acid receptor 4
LRRC40 leucine rich repeat containing 40
LTC4S leukotriene C4 synthase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MIIP migration and invasion inhibitory protein
MSR1 macrophage scavenger receptor 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEBL nebulette
NR2C1 nuclear receptor subfamily 2, group C, member 1
NRG1 neuregulin 1
OGFR opioid growth factor receptor
OVOL1 ovo-like zinc finger 1
PAX8 paired box 8
PDAP1 PDGFA associated protein 1
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POU6F2 POU class 6 homeobox 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRB protein tyrosine phosphatase, receptor type, B
RAD51B RAD51 paralog B
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RFTN1 raftlin, lipid raft linker 1
RGS12 regulator of G-protein signaling 12
RNF24 ring finger protein 24
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SFRP5 secreted frizzled-related protein 5
SH2D4A SH2 domain containing 4A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNORA21 small nucleolar RNA, H/ACA box 21
SOX15 SRY (sex determining region Y)-box 15
SP110 SP110 nuclear body protein
SYK spleen tyrosine kinase
SYNJ2 synaptojanin 2
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TK2 thymidine kinase 2, mitochondrial
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM120B transmembrane protein 120B
TMPRSS4 transmembrane protease, serine 4
TRIM5 tripartite motif containing 5
ZCCHC10 zinc finger, CCHC domain containing 10
ZCCHC14 zinc finger, CCHC domain containing 14
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF639 zinc finger protein 639
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
ACADSB acyl-CoA dehydrogenase, short/branched chain
ARRB2 arrestin, beta 2
ASB7 ankyrin repeat and SOCS box containing 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDK20 cyclin-dependent kinase 20
CLK4 CDC-like kinase 4
CRABP1 cellular retinoic acid binding protein 1
ECHDC2 enoyl CoA hydratase domain containing 2
EFHD2 EF-hand domain family, member D2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FA2H fatty acid 2-hydroxylase
FBXO22 F-box protein 22
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMO4 flavin containing monooxygenase 4
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRS2 fibroblast growth factor receptor substrate 2
FXN frataxin
GLTP glycolipid transfer protein
GMEB1 glucocorticoid modulatory element binding protein 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AM histone cluster 1, H2am
HIST1H2BE histone cluster 1, H2be
HIST1H3H histone cluster 1, H3h
HOXC10 homeobox C10
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IREB2 iron-responsive element binding protein 2
IRF7 interferon regulatory factor 7
KAT2A K(lysine) acetyltransferase 2A
KCNK15 potassium channel, two pore domain subfamily K, member 15
LINC00115 long intergenic non-protein coding RNA 115
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
LRRC8E leucine rich repeat containing 8 family, member E
LYPD3 LY6/PLAUR domain containing 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MFAP2 microfibrillar-associated protein 2
MIR22HG MIR22 host gene
MRPL44 mitochondrial ribosomal protein L44
NABP2 nucleic acid binding protein 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFE2L3 nuclear factor, erythroid 2-like 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARD6A par-6 family cell polarity regulator alpha
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PMP22 peripheral myelin protein 22
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PYCRL pyrroline-5-carboxylate reductase-like
RAB33B RAB33B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RNF170 ring finger protein 170
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
S100A4 S100 calcium binding protein A4
SAV1 salvador family WW domain containing protein 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35F6 solute carrier family 35, member F6
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SNX16 sorting nexin 16
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYBU syntabulin (syntaxin-interacting)
SYNJ2BP synaptojanin 2 binding protein
TCTN1 tectonic family member 1
TEFM transcription elongation factor, mitochondrial
TMEM260 transmembrane protein 260
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAPPC2 trafficking protein particle complex 2
TSPAN15 tetraspanin 15
TSPAN5 tetraspanin 5
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
WDR4 WD repeat domain 4
WRAP73 WD repeat containing, antisense to TP73
ZBED8 zinc finger, BED-type containing 8
ZBTB22 zinc finger and BTB domain containing 22
ZNF14 zinc finger protein 14
ZNF268 zinc finger protein 268
ZNF408 zinc finger protein 408
ZNF443 zinc finger protein 443
ZNF552 zinc finger protein 552
ZNF562 zinc finger protein 562
ZNF668 zinc finger protein 668
ZNF672 zinc finger protein 672
ZNF778 zinc finger protein 778
ZNF85 zinc finger protein 85