5255229-833 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 5255229-833 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AHCYL2 adenosylhomocysteinase-like 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C14ORF1 chromosome 14 open reading frame 1
C14ORF105 chromosome 14 open reading frame 105
CACYBP calcyclin binding protein
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCP110 centriolar coiled coil protein 110kDa
CPTP ceramide-1-phosphate transfer protein
CTH cystathionine gamma-lyase
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
DIO2 deiodinase, iodothyronine, type II
DLX2 distal-less homeobox 2
EML2 echinoderm microtubule associated protein like 2
EVI5 ecotropic viral integration site 5
FBLN1 fibulin 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLJ11292
FLT4 fms-related tyrosine kinase 4
FNDC3A fibronectin type III domain containing 3A
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GRM8 glutamate receptor, metabotropic 8
HCFC1 host cell factor C1
HPR haptoglobin-related protein
IDS iduronate 2-sulfatase
IFT74 intraflagellar transport 74
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
ITSN1 intersectin 1 (SH3 domain protein)
KIAA0485 uncharacterized LOC57235
LAMP1 lysosomal-associated membrane protein 1
LRRC40 leucine rich repeat containing 40
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
LYRM9 LYR motif containing 9
MAP1A microtubule-associated protein 1A
MARS methionyl-tRNA synthetase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MIIP migration and invasion inhibitory protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MZT2B mitotic spindle organizing protein 2B
NAG18 NAG18 mRNA
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NKX3-2 NK3 homeobox 2
NLGN1 neuroligin 1
OGFR opioid growth factor receptor
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PAX8 paired box 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PFDN6 prefoldin subunit 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKD2L2 polycystic kidney disease 2-like 2
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PSEN2 presenilin 2
PVT1 Pvt1 oncogene (non-protein coding)
RAPSN receptor-associated protein of the synapse
RBL1 retinoblastoma-like 1
RIMS2 regulating synaptic membrane exocytosis 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RYR2 ryanodine receptor 2 (cardiac)
SAPCD1 suppressor APC domain containing 1
SH3BP2 SH3-domain binding protein 2
SIM2 single-minded family bHLH transcription factor 2
SIPA1 signal-induced proliferation-associated 1
SMR3A submaxillary gland androgen regulated protein 3A
SOX12 SRY (sex determining region Y)-box 12
SPN sialophorin
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRI sorcin
STYK1 serine/threonine/tyrosine kinase 1
TADA2A transcriptional adaptor 2A
TLE2 transducin-like enhancer of split 2
TMPRSS4 transmembrane protease, serine 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53I11 tumor protein p53 inducible protein 11
TRIO trio Rho guanine nucleotide exchange factor
TSC22D4 TSC22 domain family, member 4
TTLL5 tubulin tyrosine ligase-like family member 5
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP27X ubiquitin specific peptidase 27, X-linked
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VASH2 vasohibin 2
VIPR2 vasoactive intestinal peptide receptor 2
YY2 YY2 transcription factor
ZNF407 zinc finger protein 407
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
ADGRE5 adhesion G protein-coupled receptor E5
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB1 arrestin, beta 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C1ORF56 chromosome 1 open reading frame 56
C22ORF29 chromosome 22 open reading frame 29
CCDC91 coiled-coil domain containing 91
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKN2AIP CDKN2A interacting protein
CEP72 centrosomal protein 72kDa
CFD complement factor D (adipsin)
CLK4 CDC-like kinase 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSTA cystatin A (stefin A)
CTAGE9 CTAGE family, member 9
CTSK cathepsin K
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DEPDC1 DEP domain containing 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERCC4 excision repair cross-complementation group 4
FA2H fatty acid 2-hydroxylase
FAM155B family with sequence similarity 155, member B
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FCHO1 FCH domain only 1
FGGY FGGY carbohydrate kinase domain containing
FILIP1L filamin A interacting protein 1-like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB2 GRB2-associated binding protein 2
GALK1 galactokinase 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTPBP8 GTP-binding protein 8 (putative)
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC10 homeobox C10
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAT2B K(lysine) acetyltransferase 2B
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIZ kizuna centrosomal protein
MANSC1 MANSC domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MRPL44 mitochondrial ribosomal protein L44
MTCL1 microtubule crosslinking factor 1
MVD mevalonate (diphospho) decarboxylase
NFE2L3 nuclear factor, erythroid 2-like 3
NUBPL nucleotide binding protein-like
NUPL2 nucleoporin like 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PANK4 pantothenate kinase 4
PNRC1 proline-rich nuclear receptor coactivator 1
PODXL podocalyxin-like
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR7 proline rich 7 (synaptic)
PYCRL pyrroline-5-carboxylate reductase-like
REPS2 RALBP1 associated Eps domain containing 2
RPGR retinitis pigmentosa GTPase regulator
S100A4 S100 calcium binding protein A4
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A40 solute carrier family 25, member 40
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC41A3 solute carrier family 41, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNHG3 small nucleolar RNA host gene 3
SP1 Sp1 transcription factor
SPIN1 spindlin 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THAP1 THAP domain containing, apoptosis associated protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMPRSS3 transmembrane protease, serine 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAPPC6A trafficking protein particle complex 6A
TWF2 twinfilin actin binding protein 2
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFB vascular endothelial growth factor B
ZNF273 zinc finger protein 273
ZNF329 zinc finger protein 329
ZNF574 zinc finger protein 574
ZNF586 zinc finger protein 586
ZNF813 zinc finger protein 813
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN31 zinc finger and SCAN domain containing 31