| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the 5255229-949 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BRAP | BRCA1 associated protein |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDKN2AIP | CDKN2A interacting protein |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM198B | family with sequence similarity 198, member B |
| FANCA | Fanconi anemia, complementation group A |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| FOXO1 | forkhead box O1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| ICAM1 | intercellular adhesion molecule 1 |
| INHBE | inhibin, beta E |
| IQCK | IQ motif containing K |
| IRF1 | interferon regulatory factor 1 |
| IRF9 | interferon regulatory factor 9 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLF10 | Kruppel-like factor 10 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LIF | leukemia inhibitory factor |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LPIN1 | lipin 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MBD1 | methyl-CpG binding domain protein 1 |
| MED6 | mediator complex subunit 6 |
| MIR22HG | MIR22 host gene |
| MT1G | metallothionein 1G |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NGLY1 | N-glycanase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OPTN | optineurin |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB32 | RAB32, member RAS oncogene family |
| RCAN1 | regulator of calcineurin 1 |
| RND1 | Rho family GTPase 1 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL10 | ribosomal protein L10 |
| SEC24D | SEC24 family member D |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SP110 | SP110 nuclear body protein |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAZ | tafazzin |
| TMEM53 | transmembrane protein 53 |
| TNF | tumor necrosis factor |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TSPYL2 | TSPY-like 2 |
| UBQLN4 | ubiquilin 4 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFA | vascular endothelial growth factor A |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACYP2 | acylphosphatase 2, muscle type |
| ADRA2C | adrenoceptor alpha 2C |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| APOC1 | apolipoprotein C-I |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATG9A | autophagy related 9A |
| BMP4 | bone morphogenetic protein 4 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DUSP8 | dual specificity phosphatase 8 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPHA4 | EPH receptor A4 |
| FAM63A | family with sequence similarity 63, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBRS | fibrosin |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLCE | glucuronic acid epimerase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| H2AFY2 | H2A histone family, member Y2 |
| ICK | intestinal cell (MAK-like) kinase |
| IGFLR1 | IGF-like family receptor 1 |
| IRF2 | interferon regulatory factor 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| METTL2B | methyltransferase like 2B |
| MGST3 | microsomal glutathione S-transferase 3 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXTR | oxytocin receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGP | phosphoglycolate phosphatase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PSKH1 | protein serine kinase H1 |
| PTGES2 | prostaglandin E synthase 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRAGB | Ras-related GTP binding B |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX16 | sorting nexin 16 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SP140L | SP140 nuclear body protein-like |
| STXBP2 | syntaxin binding protein 2 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBC1D12 | TBC1 domain family, member 12 |
| TEX264 | testis expressed 264 |
| THAP7 | THAP domain containing 7 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| TWF2 | twinfilin actin binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH1 | vasohibin 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR25 | WD repeat domain 25 |
| WDR4 | WD repeat domain 4 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF282 | zinc finger protein 282 |
| ZNF492 | zinc finger protein 492 |
| ZNF580 | zinc finger protein 580 |
| ZNF639 | zinc finger protein 639 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
