5286656-889 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5286656-889 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AFAP1 actin filament associated protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALPI alkaline phosphatase, intestinal
AMH anti-Mullerian hormone
ANKRD6 ankyrin repeat domain 6
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPH aspartate beta-hydroxylase
BCORL1 BCL6 corepressor-like 1
BIN1 bridging integrator 1
BTN3A3 butyrophilin, subfamily 3, member A3
C1ORF159 chromosome 1 open reading frame 159
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCP110 centriolar coiled coil protein 110kDa
CDK18 cyclin-dependent kinase 18
CLCN7 chloride channel, voltage-sensitive 7
CLIC2 chloride intracellular channel 2
CLSTN2 calsyntenin 2
COL1A1 collagen, type I, alpha 1
CSPP1 centrosome and spindle pole associated protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCLK2 doublecortin-like kinase 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLX2 distal-less homeobox 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP10 dual specificity phosphatase 10
EDAR ectodysplasin A receptor
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EVI5 ecotropic viral integration site 5
FCMR Fc fragment of IgM receptor
FGF23 fibroblast growth factor 23
FHL1 four and a half LIM domains 1
GIF gastric intrinsic factor (vitamin B synthesis)
GJA8 gap junction protein, alpha 8, 50kDa
GOLGA2 golgin A2
GPC3 glypican 3
GSK3A glycogen synthase kinase 3 alpha
GSPT1 G1 to S phase transition 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
IBSP integrin-binding sialoprotein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLHL22 kelch-like family member 22
MAG myelin associated glycoprotein
MLX MLX, MAX dimerization protein
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPPE1 metallophosphoesterase 1
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NLGN1 neuroligin 1
NOL12 nucleolar protein 12
NRF1 nuclear respiratory factor 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSGIN1 oxidative stress induced growth inhibitor 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLK4 polo-like kinase 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRMT2IP PRMT2 interacting protein
PROL1 proline rich, lacrimal 1
PRUNE2 prune homolog 2 (Drosophila)
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RCAN1 regulator of calcineurin 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC24D SEC24 family member D
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SPRED2 sprouty-related, EVH1 domain containing 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STAT5B signal transducer and activator of transcription 5B
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
TADA2A transcriptional adaptor 2A
TH tyrosine hydroxylase
TIGD6 tigger transposable element derived 6
TMEM19 transmembrane protein 19
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP3A topoisomerase (DNA) III alpha
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
TUBGCP3 tubulin, gamma complex associated protein 3
UBTD1 ubiquitin domain containing 1
VCAN versican
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF268 zinc finger protein 268
ZNF37BP zinc finger protein 37B, pseudogene
ZNF532 zinc finger protein 532
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
ARMC6 armadillo repeat containing 6
ASB7 ankyrin repeat and SOCS box containing 7
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BBS7 Bardet-Biedl syndrome 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
C10ORF88 chromosome 10 open reading frame 88
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CAMKMT calmodulin-lysine N-methyltransferase
CCNO cyclin O
CHKB choline kinase beta
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF16 DDB1 and CUL4 associated factor 16
DNALI1 dynein, axonemal, light intermediate chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EAF2 ELL associated factor 2
ETAA1 Ewing tumor-associated antigen 1
FBXO3 F-box protein 3
FILIP1L filamin A interacting protein 1-like
FLJ22184
FMO4 flavin containing monooxygenase 4
GDAP1 ganglioside induced differentiation associated protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTPBP2 GTP binding protein 2
GTPBP6 GTP binding protein 6 (putative)
HIRA histone cell cycle regulator
HIST1H2BF histone cluster 1, H2bf
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
IPP intracisternal A particle-promoted polypeptide
JAK2 Janus kinase 2
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
LOC100272216 uncharacterized LOC100272216
LYPD3 LY6/PLAUR domain containing 3
MAP9 microtubule-associated protein 9
MAPK12 mitogen-activated protein kinase 12
MED15 mediator complex subunit 15
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MT1H metallothionein 1H
NAG18 NAG18 mRNA
NECAB3 N-terminal EF-hand calcium binding protein 3
NLK nemo-like kinase
NLRX1 NLR family member X1
NPY1R neuropeptide Y receptor Y1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OLFML3 olfactomedin-like 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHB3 protocadherin beta 3
PDZK1 PDZ domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PRB3 proline-rich protein BstNI subfamily 3
RAB23 RAB23, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RBL1 retinoblastoma-like 1
REPS2 RALBP1 associated Eps domain containing 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RPGR retinitis pigmentosa GTPase regulator
RWDD3 RWD domain containing 3
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A9 solute carrier family 12, member 9
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SSFA2 sperm specific antigen 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STIM1 stromal interaction molecule 1
SYT17 synaptotagmin XVII
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMC5 transmembrane channel-like 5
TMEM159 transmembrane protein 159
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6NL USP6 N-terminal like
VEGFB vascular endothelial growth factor B
WDR7 WD repeat domain 7
WDR76 WD repeat domain 76
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF253 zinc finger protein 253