5637 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

283 genes with high or low expression in 5637 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
TATDN2 TatD DNase domain containing 2 3.60177
BRPF1 bromodomain and PHD finger containing, 1 3.60177
CCL13 chemokine (C-C motif) ligand 13 3.53297
E2F3 E2F transcription factor 3 3.01936
SETD5 SET domain containing 5 2.72287
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.67545
HBEGF heparin-binding EGF-like growth factor 2.66381
EMC3 ER membrane protein complex subunit 3 2.60956
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2.5934
MKRN2 makorin ring finger protein 2 2.56179
HRH1 histamine receptor H1 2.53452
WNT7A wingless-type MMTV integration site family, member 7A 2.28732
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.24941
MMP28 matrix metallopeptidase 28 2.20549
SEC13 SEC13 homolog (S. cerevisiae) 2.13329
MRPL39 mitochondrial ribosomal protein L39 2.06838
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.03163
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.02487
IL1A interleukin 1, alpha 1.9861
IL36G interleukin 36, gamma 1.96705
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.94657
SURF2 surfeit 2 1.89744
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.88379
IFT22 intraflagellar transport 22 1.86716
TADA3 transcriptional adaptor 3 1.86656
ANKLE2 ankyrin repeat and LEM domain containing 2 1.85433
MED17 mediator complex subunit 17 1.83719
GAREM GRB2 associated, regulator of MAPK1 1.80086
IFT74 intraflagellar transport 74 1.77163
ZNF207 zinc finger protein 207 1.75792
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.718
CCDC93 coiled-coil domain containing 93 1.71284
THBD thrombomodulin 1.69439
LRRC49 leucine rich repeat containing 49 1.68029
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 1.67173
OGG1 8-oxoguanine DNA glycosylase 1.65709
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 1.64793
PFDN1 prefoldin subunit 1 1.64356
DCTD dCMP deaminase 1.63254
AP4M1 adaptor-related protein complex 4, mu 1 subunit 1.60149
CCDC90B coiled-coil domain containing 90B 1.59877
PANK2 pantothenate kinase 2 1.59866
RIOK3 RIO kinase 3 1.57259
USP39 ubiquitin specific peptidase 39 1.55776
TIMP4 TIMP metallopeptidase inhibitor 4 1.55527
ZNHIT3 zinc finger, HIT-type containing 3 1.55164
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.52707
IL11 interleukin 11 1.5161
BIRC2 baculoviral IAP repeat containing 2 1.51503
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.50097
MCOLN3 mucolipin 3 1.49885
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.48033
GOSR2 golgi SNAP receptor complex member 2 1.47713
TUBGCP3 tubulin, gamma complex associated protein 3 1.47227
ATF3 activating transcription factor 3 1.45935
AKAP5 A kinase (PRKA) anchor protein 5 1.45721
IL1B interleukin 1, beta 1.45619
NXT1 nuclear transport factor 2-like export factor 1 1.45271
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 1.45165
WISP3 WNT1 inducible signaling pathway protein 3 1.44808
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.43985
GCC1 GRIP and coiled-coil domain containing 1 1.42577
MORC3 MORC family CW-type zinc finger 3 1.4252

low expression

Symbol Name Standardized Value
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -3.53717
ACBD4 acyl-CoA binding domain containing 4 -3.53639
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -3.1154
RPL39L ribosomal protein L39-like -3.02552
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.93314
FHOD1 formin homology 2 domain containing 1 -2.92083
HIST1H4A histone cluster 1, H4a -2.8425
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 -2.77157
DPYSL4 dihydropyrimidinase-like 4 -2.76284
MYEF2 myelin expression factor 2 -2.73857
POU1F1 POU class 1 homeobox 1 -2.68945
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 -2.67363
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.64764
MUC3B mucin 3B, cell surface associated -2.63439
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.52136
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 -2.46582
LIPC lipase, hepatic -2.4551
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.45259
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.43295
JAKMIP2 janus kinase and microtubule interacting protein 2 -2.41501
A4GNT alpha-1,4-N-acetylglucosaminyltransferase -2.38345
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.3793
CHRND cholinergic receptor, nicotinic, delta (muscle) -2.37871
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.36455
USP53 ubiquitin specific peptidase 53 -2.36096
PDPN podoplanin -2.35953
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.3452
CELA2B chymotrypsin-like elastase family, member 2B -2.32874
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.29273
SH2D1A SH2 domain containing 1A -2.28712
PAQR6 progestin and adipoQ receptor family member VI -2.28256
AR androgen receptor -2.27628
CCDC71 coiled-coil domain containing 71 -2.25595
PROM1 prominin 1 -2.24976
SCN10A sodium channel, voltage gated, type X alpha subunit -2.21892
COL19A1 collagen, type XIX, alpha 1 -2.20047
KIAA1024 KIAA1024 -2.19286
NCALD neurocalcin delta -2.18961
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) -2.16593
HABP2 hyaluronan binding protein 2 -2.164
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -2.14772
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -2.14273
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.12407
SETD1A SET domain containing 1A -2.11916
TRIM48 tripartite motif containing 48 -2.11798
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.11386
DUSP9 dual specificity phosphatase 9 -2.10163
DNAH7 dynein, axonemal, heavy chain 7 -2.09892
PODXL2 podocalyxin-like 2 -2.08528
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -2.05824
PKNOX2 PBX/knotted 1 homeobox 2 -2.03419
GABARAP GABA(A) receptor-associated protein -2.02804
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -2.0174
RFPL1S RFPL1 antisense RNA 1 -2.01177
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -1.9939
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.99334
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -1.98827
F13A1 coagulation factor XIII, A1 polypeptide -1.98531
LPPR2 lipid phosphate phosphatase-related protein type 2 -1.98421
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -1.97356
RAB5B RAB5B, member RAS oncogene family -1.96804
UNC93A unc-93 homolog A (C. elegans) -1.96221
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -1.95342
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -1.94491
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -1.94402
SSBP3 single stranded DNA binding protein 3 -1.93434
MORN1 MORN repeat containing 1 -1.91909
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -1.91319
AGXT alanine-glyoxylate aminotransferase -1.90968
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -1.90793
ZEB1 zinc finger E-box binding homeobox 1 -1.90226
CHAT choline O-acetyltransferase -1.89958
ZMYM3 zinc finger, MYM-type 3 -1.89289
ADAP2 ArfGAP with dual PH domains 2 -1.87122
GAMT guanidinoacetate N-methyltransferase -1.86694
MYOM1 myomesin 1 -1.84167
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -1.84009
DZIP3 DAZ interacting zinc finger protein 3 -1.83964
PRTN3 proteinase 3 -1.82901
TM4SF4 transmembrane 4 L six family member 4 -1.82773
TPI1 triosephosphate isomerase 1 -1.82628
SPTA1 spectrin, alpha, erythrocytic 1 -1.82312
KEL Kell blood group, metallo-endopeptidase -1.81958
EDN3 endothelin 3 -1.79939
CSN2 casein beta -1.79556
PTGDR prostaglandin D2 receptor (DP) -1.78789
HOXC4 homeobox C4 -1.7878
CCL21 chemokine (C-C motif) ligand 21 -1.78419
THEG theg spermatid protein -1.78392
PRX periaxin -1.78203
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -1.78077
ARID5A AT rich interactive domain 5A (MRF1-like) -1.77023
FRZB frizzled-related protein -1.7618
ZMYND11 zinc finger, MYND-type containing 11 -1.75491
SP140 SP140 nuclear body protein -1.75033
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 -1.74653
LMO1 LIM domain only 1 (rhombotin 1) -1.74429
ALDOA aldolase A, fructose-bisphosphate -1.74137
CLCA1 chloride channel accessory 1 -1.74044
F13B coagulation factor XIII, B polypeptide -1.73892
MNDA myeloid cell nuclear differentiation antigen -1.73362
BMP3 bone morphogenetic protein 3 -1.7285
IL10RA interleukin 10 receptor, alpha -1.72657
MKRN3 makorin ring finger protein 3 -1.71971
KLHL26 kelch-like family member 26 -1.7155
BMP10 bone morphogenetic protein 10 -1.70464
C5AR1 complement component 5a receptor 1 -1.70367
INSM1 insulinoma-associated 1 -1.70248
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.69758
GPR135 G protein-coupled receptor 135 -1.6975
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 -1.6935
TCEAL2 transcription elongation factor A (SII)-like 2 -1.69222
S1PR5 sphingosine-1-phosphate receptor 5 -1.68981
DNAH2 dynein, axonemal, heavy chain 2 -1.68653
SYN3 synapsin III -1.68521
PYY peptide YY -1.68028
CLUL1 clusterin-like 1 (retinal) -1.6697
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 -1.66724
IRX5 iroquois homeobox 5 -1.6603
NIN ninein (GSK3B interacting protein) -1.65819
ACTL8 actin-like 8 -1.658
SPARCL1 SPARC-like 1 (hevin) -1.65557
PTTG2 pituitary tumor-transforming 2 -1.65357
FOXB1 forkhead box B1 -1.65339
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -1.65256
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -1.65119
ADGRE2 adhesion G protein-coupled receptor E2 -1.64921
TRPC6 transient receptor potential cation channel, subfamily C, member 6 -1.64668
MYO1A myosin IA -1.64629
HSPB8 heat shock 22kDa protein 8 -1.646
SOCS7 suppressor of cytokine signaling 7 -1.64466
ACTC1 actin, alpha, cardiac muscle 1 -1.64396
MYL7 myosin, light chain 7, regulatory -1.64356
WNT1 wingless-type MMTV integration site family, member 1 -1.64347
TBX1 T-box 1 -1.63948
CDX4 caudal type homeobox 4 -1.63566
DIO1 deiodinase, iodothyronine, type I -1.63527
ZNF276 zinc finger protein 276 -1.63434
KLRC4 killer cell lectin-like receptor subfamily C, member 4 -1.62462
NPR1 natriuretic peptide receptor 1 -1.62382
TNS4 tensin 4 -1.61916
DNAAF1 dynein, axonemal, assembly factor 1 -1.61654
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -1.61381
RECK reversion-inducing-cysteine-rich protein with kazal motifs -1.61195
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -1.60571
CHD2 chromodomain helicase DNA binding protein 2 -1.60418
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -1.604
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 -1.60256
CDC42SE2 CDC42 small effector 2 -1.60205
FABP7 fatty acid binding protein 7, brain -1.60119
IGSF1 immunoglobulin superfamily, member 1 -1.60023
MRPS18B mitochondrial ribosomal protein S18B -1.59974
CMTR1 cap methyltransferase 1 -1.59383
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -1.59217
ZNF174 zinc finger protein 174 -1.58884
ZP2 zona pellucida glycoprotein 2 (sperm receptor) -1.58639
MRAS muscle RAS oncogene homolog -1.58635
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.5846
MXD3 MAX dimerization protein 3 -1.58342
ALAS2 5'-aminolevulinate synthase 2 -1.58276
SSR1 signal sequence receptor, alpha -1.57886
DKK4 dickkopf WNT signaling pathway inhibitor 4 -1.57439
PDZRN3 PDZ domain containing ring finger 3 -1.57135
AQP7 aquaporin 7 -1.57085
BPIFA1 BPI fold containing family A, member 1 -1.56461
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -1.55579
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -1.55432
ZMAT3 zinc finger, matrin-type 3 -1.55193
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -1.55091
LARGE like-glycosyltransferase -1.55041
GJB1 gap junction protein, beta 1, 32kDa -1.5499
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.53365
RAG2 recombination activating gene 2 -1.53159
RAI2 retinoic acid induced 2 -1.53019
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -1.52695
KRT9 keratin 9, type I -1.52384
MOCS1 molybdenum cofactor synthesis 1 -1.52006
PKLR pyruvate kinase, liver and RBC -1.50995
NLRP1 NLR family, pyrin domain containing 1 -1.50813
TACR2 tachykinin receptor 2 -1.50447
PCP4 Purkinje cell protein 4 -1.50446
CRISP3 cysteine-rich secretory protein 3 -1.50257
TBC1D10B TBC1 domain family, member 10B -1.501
TEC tec protein tyrosine kinase -1.50087
MSR1 macrophage scavenger receptor 1 -1.50038
DCN decorin -1.49996
CCND2 cyclin D2 -1.49981
ARHGAP28 Rho GTPase activating protein 28 -1.49458
SOX11 SRY (sex determining region Y)-box 11 -1.4936
MOG myelin oligodendrocyte glycoprotein -1.49329
PCYT1B phosphate cytidylyltransferase 1, choline, beta -1.48614
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.48222
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -1.47197
CRY2 cryptochrome circadian clock 2 -1.47134
ITM2A integral membrane protein 2A -1.47067
PCDHA9 protocadherin alpha 9 -1.46807
LPO lactoperoxidase -1.46286
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -1.46179
USP19 ubiquitin specific peptidase 19 -1.45627
GPR85 G protein-coupled receptor 85 -1.45552
CARD14 caspase recruitment domain family, member 14 -1.44412
LRRC3 leucine rich repeat containing 3 -1.44293
HIST1H2BC histone cluster 1, H2bc -1.44226
CAPNS1 calpain, small subunit 1 -1.44157
PRMT7 protein arginine methyltransferase 7 -1.43818
HUNK hormonally up-regulated Neu-associated kinase -1.43752
FTO fat mass and obesity associated -1.43479
NES nestin -1.43051
KDM8 lysine (K)-specific demethylase 8 -1.43026
SERF2 small EDRK-rich factor 2 -1.4299
GREM2 gremlin 2, DAN family BMP antagonist -1.42897
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -1.42893
GRK1 G protein-coupled receptor kinase 1 -1.42577
BARX1 BARX homeobox 1 -1.42549
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -1.42546
NTS neurotensin -1.4254
MLN motilin -1.42225
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.41847
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.41763
TXNRD2 thioredoxin reductase 2 -1.41712