5666823-609 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5666823-609 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACOX3 acyl-CoA oxidase 3, pristanoyl
AGFG2 ArfGAP with FG repeats 2
AMDHD2 amidohydrolase domain containing 2
ANO10 anoctamin 10
APOC1 apolipoprotein C-I
APOL2 apolipoprotein L, 2
APOOL apolipoprotein O-like
ARID4A AT rich interactive domain 4A (RBP1-like)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GAT3 beta-1,3-glucuronyltransferase 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C4BPA complement component 4 binding protein, alpha
CD5 CD5 molecule
CEP57 centrosomal protein 57kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN1 chimerin 1
CIAO1 cytosolic iron-sulfur assembly component 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CREBZF CREB/ATF bZIP transcription factor
CTAGE9 CTAGE family, member 9
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDIT4 DNA-damage-inducible transcript 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLG3 discs, large homolog 3 (Drosophila)
EFNB3 ephrin-B3
ERCC1 excision repair cross-complementation group 1
GP2 glycoprotein 2 (zymogen granule membrane)
GSTCD glutathione S-transferase, C-terminal domain containing
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-G major histocompatibility complex, class I, G
HN1L hematological and neurological expressed 1-like
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFRD1 interferon-related developmental regulator 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KIF18A kinesin family member 18A
KIF5A kinesin family member 5A
LIAS lipoic acid synthetase
LRRC61 leucine rich repeat containing 61
MAP4 microtubule-associated protein 4
MAPT microtubule-associated protein tau
MED9 mediator complex subunit 9
MRC2 mannose receptor, C type 2
MVK mevalonate kinase
NADK NAD kinase
NCR2 natural cytotoxicity triggering receptor 2
NELL2 NEL-like 2 (chicken)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OBSL1 obscurin-like 1
OVGP1 oviductal glycoprotein 1, 120kDa
PBX2 pre-B-cell leukemia homeobox 2
PCGF1 polycomb group ring finger 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHOX2A paired-like homeobox 2a
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKNOX2 PBX/knotted 1 homeobox 2
PLAUR plasminogen activator, urokinase receptor
PLCD1 phospholipase C, delta 1
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
QDPR quinoid dihydropteridine reductase
RAB29 RAB29, member RAS oncogene family
RGS11 regulator of G-protein signaling 11
RNF141 ring finger protein 141
RNF216 ring finger protein 216
RPS2 ribosomal protein S2
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SGK2 serum/glucocorticoid regulated kinase 2
SIDT2 SID1 transmembrane family, member 2
SIL1 SIL1 nucleotide exchange factor
SIRPA signal-regulatory protein alpha
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNX1 sorting nexin 1
STAU2 staufen double-stranded RNA binding protein 2
TBL1X transducin (beta)-like 1X-linked
TCP11L1 t-complex 11, testis-specific-like 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THY1 Thy-1 cell surface antigen
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TLDC1 TBC/LysM-associated domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TPST2 tyrosylprotein sulfotransferase 2
TRAM2 translocation associated membrane protein 2
TSC22D3 TSC22 domain family, member 3
TSHB thyroid stimulating hormone, beta
TTLL4 tubulin tyrosine ligase-like family member 4
TUBA4B tubulin, alpha 4b
UBA3 ubiquitin-like modifier activating enzyme 3
ULBP1 UL16 binding protein 1
VRK3 vaccinia related kinase 3
WDR46 WD repeat domain 46
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AEN apoptosis enhancing nuclease
AMN amnion associated transmembrane protein
APCS amyloid P component, serum
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC7 armadillo repeat containing 7
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C1ORF105 chromosome 1 open reading frame 105
C2 complement component 2
C2CD5 C2 calcium-dependent domain containing 5
CA11 carbonic anhydrase XI
CAMKV CaM kinase-like vesicle-associated
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCNE1 cyclin E1
CETN1 centrin, EF-hand protein, 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CLSTN2 calsyntenin 2
CNPY3 canopy FGF signaling regulator 3
COPZ2 coatomer protein complex, subunit zeta 2
CST8 cystatin 8 (cystatin-related epididymal specific)
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DPEP1 dipeptidase 1 (renal)
DRP2 dystrophin related protein 2
DUSP22 dual specificity phosphatase 22
EGLN1 egl-9 family hypoxia-inducible factor 1
FAM153A family with sequence similarity 153, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GMIP GEM interacting protein
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNRH2 gonadotropin-releasing hormone 2
GPR21 G protein-coupled receptor 21
GPX2 glutathione peroxidase 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
HIST1H3J histone cluster 1, H3j
HOOK1 hook microtubule-tethering protein 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF7 interferon regulatory factor 7
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
LENEP lens epithelial protein
LHX6 LIM homeobox 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAMLD1 mastermind-like domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MLXIPL MLX interacting protein-like
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAT6 N-acetyltransferase 6 (GCN5-related)
NBEAL2 neurobeachin-like 2
NPPA natriuretic peptide A
NXPH3 neurexophilin 3
OVOL1 ovo-like zinc finger 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PDZD7 PDZ domain containing 7
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
PRKCZ protein kinase C, zeta
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PYHIN1 pyrin and HIN domain family, member 1
QRICH1 glutamine-rich 1
RASL10A RAS-like, family 10, member A
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM41 RNA binding motif protein 41
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RXRG retinoid X receptor, gamma
SCAMP4 secretory carrier membrane protein 4
SH2D2A SH2 domain containing 2A
SLC16A6 solute carrier family 16, member 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SNX6 sorting nexin 6
SPON2 spondin 2, extracellular matrix protein
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMCC2 transmembrane and coiled-coil domain family 2
TNS3 tensin 3
TP53BP1 tumor protein p53 binding protein 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
WDR13 WD repeat domain 13
XDH xanthine dehydrogenase
ZBED1 zinc finger, BED-type containing 1
ZFHX4 zinc finger homeobox 4
ZNF143 zinc finger protein 143
ZNF276 zinc finger protein 276
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480