5707885-6385 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5707885-6385 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX5 arachidonate 5-lipoxygenase
ALPK1 alpha-kinase 1
ATF3 activating transcription factor 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
CALCR calcitonin receptor
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPNE7 copine VII
CREBZF CREB/ATF bZIP transcription factor
CTSE cathepsin E
CYHR1 cysteine/histidine-rich 1
DCAKD dephospho-CoA kinase domain containing
DDIT3 DNA-damage-inducible transcript 3
DENND6B DENN/MADD domain containing 6B
DOCK6 dedicator of cytokinesis 6
EDA ectodysplasin A
EGR1 early growth response 1
ELP6 elongator acetyltransferase complex subunit 6
EPS8L1 EPS8-like 1
GAB1 GRB2-associated binding protein 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR22 G protein-coupled receptor 22
GRB10 growth factor receptor-bound protein 10
GRM7 glutamate receptor, metabotropic 7
HEXA-AS1 HEXA antisense RNA 1
HFE hemochromatosis
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IGFBP3 insulin-like growth factor binding protein 3
IL17RC interleukin 17 receptor C
IL21R interleukin 21 receptor
INHBE inhibin, beta E
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
KLF6 Kruppel-like factor 6
KLHL22 kelch-like family member 22
KLHL28 kelch-like family member 28
KRT6B keratin 6B, type II
LARP4B La ribonucleoprotein domain family, member 4B
LDLR low density lipoprotein receptor
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MFAP3L microfibrillar-associated protein 3-like
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCAPH2 non-SMC condensin II complex, subunit H2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NSUN7 NOP2/Sun domain family, member 7
NUPR1 nuclear protein, transcriptional regulator, 1
PCDHA5 protocadherin alpha 5
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCSK6 proprotein convertase subtilisin/kexin type 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEC plectin
PROSC proline synthetase co-transcribed homolog (bacterial)
PTCRA pre T-cell antigen receptor alpha
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRO protein tyrosine phosphatase, receptor type, O
RAB11B RAB11B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RARG retinoic acid receptor, gamma
RBBP9 retinoblastoma binding protein 9
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RTEL1 regulator of telomere elongation helicase 1
RXRB retinoid X receptor, beta
SHOX2 short stature homeobox 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRCAP Snf2-related CREBBP activator protein
SV2A synaptic vesicle glycoprotein 2A
SYK spleen tyrosine kinase
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
THSD4 thrombospondin, type I, domain containing 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM259 transmembrane protein 259
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOX4 TOX high mobility group box family member 4
TUBB7P tubulin, beta 7, pseudogene
VARS valyl-tRNA synthetase
VLDLR very low density lipoprotein receptor
WSB1 WD repeat and SOCS box containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF214 zinc finger protein 214
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BRS3 bombesin-like receptor 3
BTNL2 butyrophilin-like 2
C11ORF1 chromosome 11 open reading frame 1
C2ORF27A chromosome 2 open reading frame 27A
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALML5 calmodulin-like 5
CCDC33 coiled-coil domain containing 33
CCL22 chemokine (C-C motif) ligand 22
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH18 cadherin 18, type 2
CDH19 cadherin 19, type 2
CEL carboxyl ester lipase
CLDN14 claudin 14
CORO7 coronin 7
CPA2 carboxypeptidase A2 (pancreatic)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
ERN2 endoplasmic reticulum to nucleus signaling 2
F13A1 coagulation factor XIII, A1 polypeptide
FAM212B family with sequence similarity 212, member B
FGF6 fibroblast growth factor 6
FLJ22184
FXYD5 FXYD domain containing ion transport regulator 5
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR143 G protein-coupled receptor 143
GPR65 G protein-coupled receptor 65
GSTTP1 glutathione S-transferase theta pseudogene 1
HOXA4 homeobox A4
HYAL3 hyaluronoglucosaminidase 3
IGSF6 immunoglobulin superfamily, member 6
IL2RG interleukin 2 receptor, gamma
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITM2C integral membrane protein 2C
ITPKA inositol-trisphosphate 3-kinase A
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK11 kallikrein-related peptidase 11
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LECT2 leukocyte cell-derived chemotaxin 2
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LINC01587 long intergenic non-protein coding RNA 1587
LMTK1 lemur tail kinase 1
LRP4 low density lipoprotein receptor-related protein 4
LY6G6D lymphocyte antigen 6 complex, locus G6D
MOGAT2 monoacylglycerol O-acyltransferase 2
MORC1 MORC family CW-type zinc finger 1
NEIL1 nei endonuclease VIII-like 1 (E. coli)
OLFML2A olfactomedin-like 2A
PAX6 paired box 6
PCDHB11 protocadherin beta 11
PGR progesterone receptor
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU3F2 POU class 3 homeobox 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAVER2 ribonucleoprotein, PTB-binding 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGSL1 regulator of G-protein signaling like 1
RNF122 ring finger protein 122
RNF39 ring finger protein 39
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A3 S100 calcium binding protein A3
SATB1 SATB homeobox 1
SDC3 syndecan 3
SH2D3C SH2 domain containing 3C
SHH sonic hedgehog
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPEG SPEG complex locus
STRA6 stimulated by retinoic acid 6
SYT13 synaptotagmin XIII
TACR3 tachykinin receptor 3
TAS2R10 taste receptor, type 2, member 10
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRIM21 tripartite motif containing 21
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPV4 transient receptor potential cation channel, subfamily V, member 4
WNT10B wingless-type MMTV integration site family, member 10B
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF506 zinc finger protein 506
ZNF613 zinc finger protein 613