5707885-6433 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5707885-6433 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTB actin, beta
ALCAM activated leukocyte cell adhesion molecule
AMBP alpha-1-microglobulin/bikunin precursor
APOLD1 apolipoprotein L domain containing 1
AQP1 aquaporin 1 (Colton blood group)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASIC4 acid sensing (proton gated) ion channel family member 4
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
C14ORF93 chromosome 14 open reading frame 93
C1ORF54 chromosome 1 open reading frame 54
CALCR calcitonin receptor
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPD carboxypeptidase D
CRTC1 CREB regulated transcription coactivator 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTSF cathepsin F
DESI2 desumoylating isopeptidase 2
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EGR1 early growth response 1
ENO1 enolase 1, (alpha)
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GNB5 guanine nucleotide binding protein (G protein), beta 5
GRM2 glutamate receptor, metabotropic 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2BD histone cluster 1, H2bd
HLA-G major histocompatibility complex, class I, G
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HN1L hematological and neurological expressed 1-like
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HSF2 heat shock transcription factor 2
IL17RC interleukin 17 receptor C
INHBE inhibin, beta E
ISG20 interferon stimulated exonuclease gene 20kDa
LDLR low density lipoprotein receptor
LINC00260 long intergenic non-protein coding RNA 260
LMF2 lipase maturation factor 2
LRP12 low density lipoprotein receptor-related protein 12
LRP2 low density lipoprotein receptor-related protein 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MED16 mediator complex subunit 16
MRPS18C mitochondrial ribosomal protein S18C
MT1F metallothionein 1F
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NADK NAD kinase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEK1 NIMA-related kinase 1
NEK9 NIMA-related kinase 9
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PICALM phosphatidylinositol binding clathrin assembly protein
PICK1 protein interacting with PRKCA 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKP3 plakophilin 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRNP prion protein
PRPF18 pre-mRNA processing factor 18
PSAT1 phosphoserine aminotransferase 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QKI QKI, KH domain containing, RNA binding
RAB5C RAB5C, member RAS oncogene family
RNF146 ring finger protein 146
RPL10 ribosomal protein L10
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOCS6 suppressor of cytokine signaling 6
SPAG4 sperm associated antigen 4
SPATA5L1 spermatogenesis associated 5-like 1
SQLE squalene epoxidase
SRSF1 serine/arginine-rich splicing factor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TCTN2 tectonic family member 2
TK2 thymidine kinase 2, mitochondrial
TMEM230 transmembrane protein 230
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM36 tripartite motif containing 36
ULBP2 UL16 binding protein 2
VLDLR very low density lipoprotein receptor
WARS tryptophanyl-tRNA synthetase
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAP2 ArfGAP with dual PH domains 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARSB arylsulfatase B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAG4 BCL2-associated athanogene 4
BAHD1 bromo adjacent homology domain containing 1
C11ORF68 chromosome 11 open reading frame 68
C19ORF73 chromosome 19 open reading frame 73
CAMKMT calmodulin-lysine N-methyltransferase
CD53 CD53 molecule
CD82 CD82 molecule
CDH18 cadherin 18, type 2
CLMN calmin (calponin-like, transmembrane)
CNTD2 cyclin N-terminal domain containing 2
CNTNAP1 contactin associated protein 1
COPS7B COP9 signalosome subunit 7B
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSC2 desmocollin 2
EGFL7 EGF-like-domain, multiple 7
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC1 exosome component 1
FAM189A2 family with sequence similarity 189, member A2
FSHB follicle stimulating hormone, beta polypeptide
GATA4 GATA binding protein 4
GID4 GID complex subunit 4
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
HPSE heparanase
ICOS inducible T-cell co-stimulator
IL17RA interleukin 17 receptor A
IP6K1 inositol hexakisphosphate kinase 1
ITPKB inositol-trisphosphate 3-kinase B
JADE3 jade family PHD finger 3
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KHK ketohexokinase (fructokinase)
KIFC1 kinesin family member C1
LINC00115 long intergenic non-protein coding RNA 115
LINC00597 long intergenic non-protein coding RNA 597
LOC100287590 uncharacterized LOC100287590
LRRC61 leucine rich repeat containing 61
MEGF8 multiple EGF-like-domains 8
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NT5E 5'-nucleotidase, ecto (CD73)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OXCT2 3-oxoacid CoA transferase 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHB3 protocadherin beta 3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RECQL4 RecQ protein-like 4
SHPK sedoheptulokinase
SIX1 SIX homeobox 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLN sarcolipin
SNTA1 syntrophin, alpha 1
SPATA2L spermatogenesis associated 2-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STK16 serine/threonine kinase 16
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D2 TBC1 domain family, member 2
TICAM1 toll-like receptor adaptor molecule 1
TM4SF5 transmembrane 4 L six family member 5
TSC22D4 TSC22 domain family, member 4
TXLNG taxilin gamma
VAX2 ventral anterior homeobox 2
WDR76 WD repeat domain 76
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF205 zinc finger protein 205
ZNF358 zinc finger protein 358
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701