5707885-6438 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 5707885-6438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2B activin A receptor, type IIB
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKMY1 ankyrin repeat and MYND domain containing 1
APP amyloid beta (A4) precursor protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASB1 ankyrin repeat and SOCS box containing 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
ATF7IP2 activating transcription factor 7 interacting protein 2
BCL2L2 BCL2-like 2
C17ORF53 chromosome 17 open reading frame 53
CA5B carbonic anhydrase VB, mitochondrial
CCDC93 coiled-coil domain containing 93
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDND1 claudin domain containing 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CRY2 cryptochrome circadian clock 2
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM129A family with sequence similarity 129, member A
FAM188A family with sequence similarity 188, member A
FERMT2 fermitin family member 2
FLCN folliculin
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDAP1 ganglioside induced differentiation associated protein 1
GK glycerol kinase
GLRB glycine receptor, beta
GPM6B glycoprotein M6B
GPR1 G protein-coupled receptor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AJ histone cluster 1, H2aj
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL6 interleukin 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIF16B kinesin family member 16B
KLHL24 kelch-like family member 24
LMAN1 lectin, mannose-binding, 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MET MET proto-oncogene, receptor tyrosine kinase
MT1X metallothionein 1X
MYO1B myosin IB
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
PTK2B protein tyrosine kinase 2 beta
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAPCD1 suppressor APC domain containing 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQSTM1 sequestosome 1
SRCAP Snf2-related CREBBP activator protein
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
STC2 stanniocalcin 2
THBD thrombomodulin
TMEM231 transmembrane protein 231
TRIB3 tribbles pseudokinase 3
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UBOX5 U-box domain containing 5
ZBTB1 zinc finger and BTB domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADGRF1 adhesion G protein-coupled receptor F1
ADRA2B adrenoceptor alpha 2B
AHDC1 AT hook, DNA binding motif, containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BTBD18 BTB (POZ) domain containing 18
C16ORF45 chromosome 16 open reading frame 45
C1QB complement component 1, q subcomponent, B chain
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
C8B complement component 8, beta polypeptide
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCNJL cyclin J-like
CFAP44 cilia and flagella associated protein 44
CHML choroideremia-like (Rab escort protein 2)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEB cell death-inducing DFFA-like effector b
CLCA1 chloride channel accessory 1
COBL cordon-bleu WH2 repeat protein
COL9A3 collagen, type IX, alpha 3
EPHB3 EPH receptor B3
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM120C family with sequence similarity 120C
FGF9 fibroblast growth factor 9
GK2 glycerol kinase 2
GMIP GEM interacting protein
GRAP GRB2-related adaptor protein
GRPR gastrin-releasing peptide receptor
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HHAT hedgehog acyltransferase
HIRA histone cell cycle regulator
HIST1H3G histone cluster 1, H3g
HIST1H3I histone cluster 1, H3i
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC10 homeobox C10
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPB8 heat shock 22kDa protein 8
IFI44L interferon-induced protein 44-like
ITPKA inositol-trisphosphate 3-kinase A
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
KIF20B kinesin family member 20B
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
KRT86 keratin 86, type II
LHB luteinizing hormone beta polypeptide
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCMBP minichromosome maintenance complex binding protein
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MUC3B mucin 3B, cell surface associated
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPFFR1 neuropeptide FF receptor 1
NPR3 natriuretic peptide receptor 3
NTSR1 neurotensin receptor 1 (high affinity)
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMFBP1 polyamine modulated factor 1 binding protein 1
PRAMEF11 PRAME family member 11
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3A RAB3A, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RUNX1-IT1 RUNX1 intronic transcript 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SDS serine dehydratase
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOBP sine oculis binding protein homolog (Drosophila)
ST5 suppression of tumorigenicity 5
SYNPO synaptopodin
TBXAS1 thromboxane A synthase 1 (platelet)
TDRD1 tudor domain containing 1
TMEM121 transmembrane protein 121
TMEM156 transmembrane protein 156
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM9 tripartite motif containing 9
TXNIP thioredoxin interacting protein
UBQLN4 ubiquilin 4
UNC13A unc-13 homolog A (C. elegans)
VASH2 vasohibin 2
YY2 YY2 transcription factor
ZCCHC2 zinc finger, CCHC domain containing 2
ZHX2 zinc fingers and homeoboxes 2
ZNF107 zinc finger protein 107
ZNF215 zinc finger protein 215
ZNF358 zinc finger protein 358