59M Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
Description High-Grade Serous Ovarian Cancer cell line (Cancer Dependency Map)
External Link https://depmap.org/portal/cell_line/ACH-000520
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Genes

504 gene knockdowns changing fitness of 59M relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
POTEC POTE ankyrin domain family, member C 15.9051
PDIA5 protein disulfide isomerase family A, member 5 12.0068
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 11.5412
GLYATL1 glycine-N-acyltransferase-like 1 10.4772
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 9.4666
ADGRE5 adhesion G protein-coupled receptor E5 9.15621
EREG epiregulin 8.55323
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 8.22558
LRRC59 leucine rich repeat containing 59 7.80445
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 7.01908
SMIM8 small integral membrane protein 8 6.73244
DSE dermatan sulfate epimerase 6.513
MUC5B mucin 5B, oligomeric mucus/gel-forming 6.42346
FOXP3 forkhead box P3 6.31409
FAM161B family with sequence similarity 161, member B 6.30112
CERS3 ceramide synthase 3 6.04449
PRR4 proline rich 4 (lacrimal) 5.89604
CFP complement factor properdin 5.77329
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 5.74752
PLCH1 phospholipase C, eta 1 5.51643
TEX29 testis expressed 29 5.49181
TOB2 transducer of ERBB2, 2 5.39474
SPATA31A3 SPATA31 subfamily A, member 3 5.3746
OPRD1 opioid receptor, delta 1 5.3738
TMUB1 transmembrane and ubiquitin-like domain containing 1 5.36314
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 5.34203
TMEM86B transmembrane protein 86B 5.34039
GPX2 glutathione peroxidase 2 5.32196
KDM6B lysine (K)-specific demethylase 6B 5.30392
LCE1D late cornified envelope 1D 5.29212
CIB3 calcium and integrin binding family member 3 5.25007
IL2 interleukin 2 5.24108
NPFF neuropeptide FF-amide peptide precursor 5.23255
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 5.18952
CD8A CD8a molecule 5.16881
AGO4 argonaute RISC catalytic component 4 5.10593
OR13D1 olfactory receptor, family 13, subfamily D, member 1 5.0947
SYT5 synaptotagmin V 4.97515
DCAF11 DDB1 and CUL4 associated factor 11 4.94877
SHANK1 SH3 and multiple ankyrin repeat domains 1 4.91318
PATE1 prostate and testis expressed 1 4.84706
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 4.8364
YAF2 YY1 associated factor 2 4.83114
ZNF579 zinc finger protein 579 4.79884
EVX2 even-skipped homeobox 2 4.78251
COL17A1 collagen, type XVII, alpha 1 4.72628
CCNB3 cyclin B3 4.69529
XAGE2 X antigen family, member 2 4.6667
TMEM144 transmembrane protein 144 4.63494
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 4.60079
DGAT1 diacylglycerol O-acyltransferase 1 4.59831
HIAT1 hippocampus abundant transcript 1 4.59272
C1QTNF2 C1q and tumor necrosis factor related protein 2 4.58256
OR5T1 olfactory receptor, family 5, subfamily T, member 1 4.58181
SLC26A11 solute carrier family 26 (anion exchanger), member 11 4.58137
ZNF835 zinc finger protein 835 4.52735
CCL20 chemokine (C-C motif) ligand 20 4.4924
OR1K1 olfactory receptor, family 1, subfamily K, member 1 4.48636
CR2 complement component (3d/Epstein Barr virus) receptor 2 4.47183
RNF25 ring finger protein 25 4.47181
SMIM17 small integral membrane protein 17 4.4597
IFNLR1 interferon, lambda receptor 1 4.32849
RCN1 reticulocalbin 1, EF-hand calcium binding domain 4.32808
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 4.31403
SLC26A8 solute carrier family 26 (anion exchanger), member 8 4.30257
DCP1B decapping mRNA 1B 4.29571
MSS51 MSS51 mitochondrial translational activator 4.26083
ASIC3 acid sensing (proton gated) ion channel 3 4.24892
TRAPPC6B trafficking protein particle complex 6B 4.22289
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 4.18195
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 4.177
SCGB3A2 secretoglobin, family 3A, member 2 4.17486
ONECUT2 one cut homeobox 2 4.16995
SLC25A30 solute carrier family 25, member 30 4.16368
ZNF451 zinc finger protein 451 4.14634
C1ORF198 chromosome 1 open reading frame 198 4.13625
RAB40B RAB40B, member RAS oncogene family 4.0703
RADIL Ras association and DIL domains 4.047
ZNF671 zinc finger protein 671 4.02593
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 4.02505
OR6B2 olfactory receptor, family 6, subfamily B, member 2 4.02417
SDSL serine dehydratase-like 4.00758
MYDGF myeloid-derived growth factor 4.00285
LRGUK leucine-rich repeats and guanylate kinase domain containing 3.9857
ZBTB9 zinc finger and BTB domain containing 9 3.97219
NEURL2 neuralized E3 ubiquitin protein ligase 2 3.92907
PRSS50 protease, serine, 50 3.92478
SUMO1 small ubiquitin-like modifier 1 3.89801
DUOX2 dual oxidase 2 3.87448
METTL8 methyltransferase like 8 3.86969
NUTM2F NUT family member 2F 3.86295
VSX1 visual system homeobox 1 3.85371
PTTG1IP pituitary tumor-transforming 1 interacting protein 3.8403
SLC45A2 solute carrier family 45, member 2 3.82542
CDK5 cyclin-dependent kinase 5 3.82508
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 3.80139
MORC1 MORC family CW-type zinc finger 1 3.79383
FBN1 fibrillin 1 3.78366
TSPEAR thrombospondin-type laminin G domain and EAR repeats 3.72239
PPP1R3F protein phosphatase 1, regulatory subunit 3F 3.72029
PHEX phosphate regulating endopeptidase homolog, X-linked 3.71153
KLK9 kallikrein-related peptidase 9 3.69747
QDPR quinoid dihydropteridine reductase 3.6522
MEGF8 multiple EGF-like-domains 8 3.63475
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.61018
STX1B syntaxin 1B 3.59317
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 3.5867
UROC1 urocanate hydratase 1 3.57566
ZIC1 Zic family member 1 3.56195
PABIR2 PABIR family member 2 3.55974
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 3.54419
IGFBP7 insulin-like growth factor binding protein 7 3.52769
ZNF227 zinc finger protein 227 3.50436
MYT1L myelin transcription factor 1-like 3.47816
CPXCR1 CPX chromosome region, candidate 1 3.47629
IKBIP IKBKB interacting protein 3.47112
LTA lymphotoxin alpha 3.46074
KIFC1 kinesin family member C1 3.4347
CCDC150 coiled-coil domain containing 150 3.4235
SLCO1C1 solute carrier organic anion transporter family, member 1C1 3.42305
KRT72 keratin 72, type II 3.40736
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 3.40649
OR5AN1 olfactory receptor, family 5, subfamily AN, member 1 3.40544
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 3.38803
RIOK3 RIO kinase 3 3.3811
SSX7 synovial sarcoma, X breakpoint 7 3.35409
MOGS mannosyl-oligosaccharide glucosidase 3.35061
VDAC3 voltage-dependent anion channel 3 3.34913
CCDC138 coiled-coil domain containing 138 3.33601
CBARP CACN subunit beta associated regulatory protein 3.32683
FAM124B family with sequence similarity 124B 3.32486
ZXDB zinc finger, X-linked, duplicated B 3.31697
LGALS12 lectin, galactoside-binding, soluble, 12 3.31512
CNKSR2 connector enhancer of kinase suppressor of Ras 2 3.31282
BOLA1 bolA family member 1 3.3002
OR10A2 olfactory receptor, family 10, subfamily A, member 2 3.29837
RAX2 retina and anterior neural fold homeobox 2 3.29566
NRSN2 neurensin 2 3.27524
ENHO energy homeostasis associated 3.27303
AMHR2 anti-Mullerian hormone receptor, type II 3.26282
ICA1 islet cell autoantigen 1, 69kDa 3.26144
SVIL supervillin 3.2583
TFCP2 transcription factor CP2 3.25476
SWI5 SWI5 recombination repair homolog (yeast) 3.2498
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 3.24266
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 3.24123
NEK6 NIMA-related kinase 6 3.23955
CCDC180 coiled-coil domain containing 180 3.23664
LITAF lipopolysaccharide-induced TNF factor 3.23038
PARP1 poly (ADP-ribose) polymerase 1 3.22693
PRSS37 protease, serine, 37 3.22487
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.22485
YIPF3 Yip1 domain family, member 3 3.21093
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 3.19343
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 3.18447
ADAM9 ADAM metallopeptidase domain 9 3.18241
PGPEP1 pyroglutamyl-peptidase I 3.15991
ACTL7A actin-like 7A 3.15989
SPATA6 spermatogenesis associated 6 3.15384
OTOP3 otopetrin 3 3.15196
PROCR protein C receptor, endothelial 3.13854
NNT nicotinamide nucleotide transhydrogenase 3.13596
FBXO10 F-box protein 10 3.11934
OR52B6 olfactory receptor, family 52, subfamily B, member 6 3.11749
IQSEC2 IQ motif and Sec7 domain 2 3.10864
ZNF775 zinc finger protein 775 3.10419
SSC4D scavenger receptor cysteine rich family, 4 domains 3.10263
KIAA1958 KIAA1958 3.09357
IL24 interleukin 24 3.08856
RETREG3 reticulophagy regulator family member 3 3.08378
TMTC4 transmembrane and tetratricopeptide repeat containing 4 3.0837
CEMIP cell migration inducing protein, hyaluronan binding 3.06627
ZBP1 Z-DNA binding protein 1 3.06367
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 3.06264
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 3.05891
SPINK4 serine peptidase inhibitor, Kazal type 4 3.05708
RETNLB resistin like beta 3.05524
S100PBP S100P binding protein 3.0484
ZNF417 zinc finger protein 417 3.04497
BEX5 brain expressed, X-linked 5 3.04473
HORMAD1 HORMA domain containing 1 3.04454
WDR34 WD repeat domain 34 3.03255
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.03234
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 3.02565
MPI mannose phosphate isomerase 3.02022
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 3.01034
PDE3B phosphodiesterase 3B, cGMP-inhibited 3.00851
SEPTIN8 septin 8 3.00822
TSSK6 testis-specific serine kinase 6 3.00554
FBXO41 F-box protein 41 3.00286
SEC11A SEC11 homolog A (S. cerevisiae) 3.00073
AKT1S1 AKT1 substrate 1 (proline-rich) 2.98769
CLEC12A C-type lectin domain family 12, member A 2.97682
C1ORF68 chromosome 1 open reading frame 68 2.9739
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.96982
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.95335
CABP7 calcium binding protein 7 2.95322
FBXO16 F-box protein 16 2.95308
PHGDH phosphoglycerate dehydrogenase 2.95288
FAM207A family with sequence similarity 207, member A 2.95183
ATF5 activating transcription factor 5 2.93582
SEC24A SEC24 family member A 2.9243
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.9176
KLHL36 kelch-like family member 36 2.91322
VRK2 vaccinia related kinase 2 2.91131
CLDN2 claudin 2 2.89361
PHF8 PHD finger protein 8 2.89299
SEC31B SEC31 homolog B (S. cerevisiae) 2.89271
SNRK SNF related kinase 2.87343
FGFR1 fibroblast growth factor receptor 1 2.86667
FRZB frizzled-related protein 2.86551
FBXO46 F-box protein 46 2.86275
SUFU suppressor of fused homolog (Drosophila) 2.86139
ARSD arylsulfatase D 2.85885
THBS2 thrombospondin 2 2.85521
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 2.85184
EPS8L3 EPS8-like 3 2.85033
PRKCSH protein kinase C substrate 80K-H 2.83763
IVL involucrin 2.83758
ZNF16 zinc finger protein 16 2.83298
GIMAP6 GTPase, IMAP family member 6 2.82576
RIC8B RIC8 guanine nucleotide exchange factor B 2.81483
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.81299
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.81087
FAM91A1 family with sequence similarity 91, member A1 2.80861
LENEP lens epithelial protein 2.80339
C19ORF18 chromosome 19 open reading frame 18 2.80183
G6PD glucose-6-phosphate dehydrogenase 2.79933
SMIM24 small integral membrane protein 24 2.79715
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.79317
HELZ helicase with zinc finger 2.78903
FFAR1 free fatty acid receptor 1 2.78767
STAT1 signal transducer and activator of transcription 1, 91kDa 2.78587
JSRP1 junctional sarcoplasmic reticulum protein 1 2.77953
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.77431
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.76108
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 2.74779
GOLM1 golgi membrane protein 1 2.74727
CTSS cathepsin S 2.7438
TMC1 transmembrane channel-like 1 2.74235
EDDM3A epididymal protein 3A 2.74211
MCRIP2 MAPK regulated corepressor interacting protein 2 2.73949
GARNL3 GTPase activating Rap/RanGAP domain-like 3 2.7336
TSPAN33 tetraspanin 33 2.72616
CCR9 chemokine (C-C motif) receptor 9 2.72376
FRMD4A FERM domain containing 4A 2.71596
CDCA2 cell division cycle associated 2 2.71502
FAM120C family with sequence similarity 120C 2.71394
PTPRB protein tyrosine phosphatase, receptor type, B 2.70823
KLHL31 kelch-like family member 31 2.70518
TMEM255B transmembrane protein 255B 2.70488
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2.70109
CCDC9B coiled-coil domain containing 9B 2.69183
UBR1 ubiquitin protein ligase E3 component n-recognin 1 2.6834
MFSD14B major facilitator superfamily domain containing 14B 2.67785
PCDHAC1 protocadherin alpha subfamily C, 1 2.67717
USP1 ubiquitin specific peptidase 1 2.66661
HK1 hexokinase 1 2.66441
FOPNL FGFR1OP N-terminal like 2.65859
HOMER3 homer scaffolding protein 3 2.65621
PARVG parvin, gamma 2.65345
ODF3L2 outer dense fiber of sperm tails 3-like 2 2.65326
NUP62CL nucleoporin 62kDa C-terminal like 2.64873
TACR1 tachykinin receptor 1 2.64255
PNPLA6 patatin-like phospholipase domain containing 6 2.6416
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 2.61856
MORN3 MORN repeat containing 3 2.60894
SPAG17 sperm associated antigen 17 2.60201
WDR86 WD repeat domain 86 2.59772
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 2.59604
GPANK1 G patch domain and ankyrin repeats 1 2.59201
YJEFN3 YjeF N-terminal domain containing 3 2.58983
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 2.58572
MEGF11 multiple EGF-like-domains 11 2.58518
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.5815
CAPN1 calpain 1, (mu/I) large subunit 2.58074
BMP8A bone morphogenetic protein 8a 2.58043
EFCAB14 EF-hand calcium binding domain 14 2.57564
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 2.57226
CEP295NL CEP295 N-terminal like 2.57037
TSLIG2 tRNA splicing ligase complex subunit 2 2.56961
C8G complement component 8, gamma polypeptide 2.56887
PFKM phosphofructokinase, muscle 2.56268
CABP1 calcium binding protein 1 2.56254
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.54929
PYCR3 pyrroline-5-carboxylate reductase 3 2.54866
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 2.54379
WSCD1 WSC domain containing 1 2.54344
C2ORF42 chromosome 2 open reading frame 42 2.53746
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.53681
TMBIM6 transmembrane BAX inhibitor motif containing 6 2.53644
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.53503
SPIDR scaffolding protein involved in DNA repair 2.53484
DCC DCC netrin 1 receptor 2.53238
OAT ornithine aminotransferase 2.53044
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2.52537
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.52492
CNGB1 cyclic nucleotide gated channel beta 1 2.52485
MCEMP1 mast cell-expressed membrane protein 1 2.52084
EIPR1 EARP complex and GARP complex interacting protein 1 2.52043
EPB41L2 erythrocyte membrane protein band 4.1-like 2 2.51916
ZP1 zona pellucida glycoprotein 1 (sperm receptor) 2.51715
PTGDR2 prostaglandin D2 receptor 2 2.51702
OR52K2 olfactory receptor, family 52, subfamily K, member 2 2.50954
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2.50357
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.49716
SYNDIG1 synapse differentiation inducing 1 2.49387
RRAS related RAS viral (r-ras) oncogene homolog 2.49282
FXR2 fragile X mental retardation, autosomal homolog 2 2.48979
C11ORF68 chromosome 11 open reading frame 68 2.48906
LURAP1L leucine rich adaptor protein 1-like 2.4856
FAM104B family with sequence similarity 104, member B 2.48547
ANK1 ankyrin 1, erythrocytic 2.48053
HOXC9 homeobox C9 2.47262
PYGL phosphorylase, glycogen, liver 2.46872
MAOB monoamine oxidase B 2.46868
CERKL ceramide kinase-like 2.46215
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.45871
CCL8 chemokine (C-C motif) ligand 8 2.4433
DGKI diacylglycerol kinase, iota 2.44218
BTBD1 BTB (POZ) domain containing 1 2.44202
TAPT1 transmembrane anterior posterior transformation 1 2.4342
PRPH peripherin 2.42681
UMOD uromodulin 2.42152
ACAN aggrecan 2.41873
MIXL1 Mix paired-like homeobox 2.41693
CCDC142 coiled-coil domain containing 142 2.41618
SLMO1 slowmo homolog 1 (Drosophila) 2.41605
TCTEX1D4 Tctex1 domain containing 4 2.41398
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 2.41308
RRH retinal pigment epithelium-derived rhodopsin homolog 2.41212
ADPRS ADP-ribosylserine hydrolase 2.41181
THOP1 thimet oligopeptidase 1 2.41179
IGFL2 IGF-like family member 2 2.41176
FCRL2 Fc receptor-like 2 2.40805
D2HGDH D-2-hydroxyglutarate dehydrogenase 2.39885
CLMP CXADR-like membrane protein 2.39634
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.39579
TENT4B terminal nucleotidyltransferase 4B 2.39575
OR51F2 olfactory receptor, family 51, subfamily F, member 2 2.38939
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.38496
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 2.38496
ATAD2 ATPase family, AAA domain containing 2 2.37899
TLL2 tolloid-like 2 2.37317
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 2.3709
CLIP3 CAP-GLY domain containing linker protein 3 2.36981
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.3688
ABRAXAS2 abraxas 2, BRISC complex subunit 2.3672
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.36163
STPG2 sperm-tail PG-rich repeat containing 2 2.36014
IMPACT impact RWD domain protein 2.35584
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.35532
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 2.35462
ALPI alkaline phosphatase, intestinal 2.34902
LRRC8C leucine rich repeat containing 8 family, member C 2.34889
FGD1 FYVE, RhoGEF and PH domain containing 1 2.34877
GPR39 G protein-coupled receptor 39 2.34592
ZFYVE19 zinc finger, FYVE domain containing 19 2.33894
CAMKV CaM kinase-like vesicle-associated 2.33746
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 2.32918
RASAL3 RAS protein activator like 3 2.32662
GANAB glucosidase, alpha; neutral AB 2.32328
MIIP migration and invasion inhibitory protein 2.31777
FAM151A family with sequence similarity 151, member A 2.31495
RAB18 RAB18, member RAS oncogene family 2.31451
FAM89B family with sequence similarity 89, member B 2.30765
INA internexin neuronal intermediate filament protein, alpha 2.30511
RHCE Rh blood group, CcEe antigens 2.30395
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.29143
NDNF neuron-derived neurotrophic factor 2.28717
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.28518
DSG3 desmoglein 3 2.28225
LCE3D late cornified envelope 3D 2.28081
RCCD1 RCC1 domain containing 1 2.27459
CD86 CD86 molecule 2.27459
SPATS2 spermatogenesis associated, serine-rich 2 2.26805
HPR haptoglobin-related protein 2.2644
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.26248
OR6M1 olfactory receptor, family 6, subfamily M, member 1 2.26207
IGSF5 immunoglobulin superfamily, member 5 2.26193
SPINK5 serine peptidase inhibitor, Kazal type 5 2.26152
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.25355
CNOT6 CCR4-NOT transcription complex, subunit 6 2.25233
CA12 carbonic anhydrase XII 2.24989
FYN FYN proto-oncogene, Src family tyrosine kinase 2.24856
LCE4A late cornified envelope 4A 2.24666
PRR22 proline rich 22 2.24107
OR10AD1 olfactory receptor, family 10, subfamily AD, member 1 2.24075
LCE1B late cornified envelope 1B 2.23017
KLHL26 kelch-like family member 26 2.22996
PAGE4 P antigen family, member 4 (prostate associated) 2.22727
CNOT11 CCR4-NOT transcription complex, subunit 11 2.22304
NEURL1B neuralized E3 ubiquitin protein ligase 1B 2.21806
ZNF195 zinc finger protein 195 2.21459
ESRRA estrogen-related receptor alpha 2.2097
SLAMF1 signaling lymphocytic activation molecule family member 1 2.20568
TRAPPC2L trafficking protein particle complex 2-like 2.20541
GON4L gon-4-like (C. elegans) 2.20537
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 2.20417
USP34 ubiquitin specific peptidase 34 2.20172
NLN neurolysin (metallopeptidase M3 family) 2.19268
IL12A interleukin 12A 2.19195
NOL4L nucleolar protein 4-like 2.18516
PCDHGA11 protocadherin gamma subfamily A, 11 2.18376
DNTT DNA nucleotidylexotransferase 2.18352
IGFBP5 insulin-like growth factor binding protein 5 2.1815
HOXD4 homeobox D4 2.17924
STK25 serine/threonine kinase 25 2.17783
DBNL drebrin-like 2.1767
ITPKA inositol-trisphosphate 3-kinase A 2.17666
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 2.17625
OR4C13 olfactory receptor, family 4, subfamily C, member 13 2.17323
XDH xanthine dehydrogenase 2.17021
C1QL2 complement component 1, q subcomponent-like 2 2.16986
TMEM262 transmembrane protein 262 2.16973
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.16693
CHST10 carbohydrate sulfotransferase 10 2.16605
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 2.16396
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 2.16319
TCF23 transcription factor 23 2.16048
PPP1R12C protein phosphatase 1, regulatory subunit 12C 2.15861
RAB5IF RAB5 interacting factor 2.15668
ZNF576 zinc finger protein 576 2.15576
SOCS4 suppressor of cytokine signaling 4 2.1484
WNK3 WNK lysine deficient protein kinase 3 2.14529
ADGRL1 adhesion G protein-coupled receptor L1 2.14423
MT1G metallothionein 1G 2.1393
PKD2L1 polycystic kidney disease 2-like 1 2.13836
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.13611
CCS copper chaperone for superoxide dismutase 2.13553
GLI2 GLI family zinc finger 2 2.12998
WBP2 WW domain binding protein 2 2.12949
GCM2 glial cells missing homolog 2 (Drosophila) 2.12796
SPATA31A7 SPATA31 subfamily A, member 7 2.12726
AIF1L allograft inflammatory factor 1-like 2.12528
SPRED2 sprouty-related, EVH1 domain containing 2 2.12435
BCL7C B-cell CLL/lymphoma 7C 2.12363
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.11859
STXBP1 syntaxin binding protein 1 2.1173
MATN3 matrilin 3 2.11693
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.11473
OR51B5 olfactory receptor, family 51, subfamily B, member 5 2.11344
NPBWR2 neuropeptides B/W receptor 2 2.11298
TOP1MT topoisomerase (DNA) I, mitochondrial 2.1102
LCE3B late cornified envelope 3B 2.10989
TEK TEK tyrosine kinase, endothelial 2.10784
ZNF862 zinc finger protein 862 2.10761
USP2 ubiquitin specific peptidase 2 2.10729
CNTF ciliary neurotrophic factor 2.10663
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.1056
CPEB3 cytoplasmic polyadenylation element binding protein 3 2.10433
AGBL3 ATP/GTP binding protein-like 3 2.10372
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.0993
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 2.09643
FAM184B family with sequence similarity 184, member B 2.09539
ZNF674 zinc finger protein 674 2.09319
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 2.08422
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.08301
ADRB3 adrenoceptor beta 3 2.07951
PRR14 proline rich 14 2.07842
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.07793
YLPM1 YLP motif containing 1 2.07657
LRIF1 ligand dependent nuclear receptor interacting factor 1 2.07567
C10ORF99 chromosome 10 open reading frame 99 2.07475
RHEBL1 Ras homolog enriched in brain like 1 2.07428
PCDHGA3 protocadherin gamma subfamily A, 3 2.06914
SIAE sialic acid acetylesterase 2.06063
FEM1C fem-1 homolog c (C. elegans) 2.05709
GLP1R glucagon-like peptide 1 receptor 2.05486
HMGB4 high mobility group box 4 2.05259
MCCD1 mitochondrial coiled-coil domain 1 2.05253
XYLT2 xylosyltransferase II 2.05148
SLC10A7 solute carrier family 10, member 7 2.04889
HAL histidine ammonia-lyase 2.04832
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2 2.04826
LCE3C late cornified envelope 3C 2.04598
HR hair growth associated 2.04403
TPCN1 two pore segment channel 1 2.04317
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.04186
ATG4C autophagy related 4C, cysteine peptidase 2.04008
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1 2.03801
GUCY2F guanylate cyclase 2F, retinal 2.03531
MEX3C mex-3 RNA binding family member C 2.03204
TMEM236 transmembrane protein 236 2.02997
HABP2 hyaluronan binding protein 2 2.02993
AMBN ameloblastin (enamel matrix protein) 2.02943
H3F3B H3 histone, family 3B (H3.3B) 2.02575
DNAAF3 dynein, axonemal, assembly factor 3 2.02551
ATM ATM serine/threonine kinase 2.02418
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 2.0233
DTX1 deltex 1, E3 ubiquitin ligase 2.02323
APOF apolipoprotein F 2.02256
ARHGAP25 Rho GTPase activating protein 25 2.02167
RAD51B RAD51 paralog B 2.02144
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2.01725
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.01501
RPUSD1 RNA pseudouridylate synthase domain containing 1 2.01468
DAW1 dynein assembly factor with WDR repeat domains 1 2.01352
ANKRD29 ankyrin repeat domain 29 2.0132
HASPIN histone H3 associated protein kinase 2.01085
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.00787
KRTAP21-2 keratin associated protein 21-2 2.00547
MPST mercaptopyruvate sulfurtransferase 2.00221
POTEF POTE ankyrin domain family, member F 2.0012