5min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations
Category proteomics
Type gene perturbation
Description gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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97 proteins differentially phosphorylated following the 5min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations dataset.

increased phosphorylation

Symbol Name
ACP1 acid phosphatase 1, soluble
ACTA1 actin, alpha 1, skeletal muscle
ADA adenosine deaminase
ADAM9 ADAM metallopeptidase domain 9
AHCY adenosylhomocysteinase
ANXA2 annexin A2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASKIN2 CASK interacting protein 2
CD247 CD247 molecule
CD84 CD84 molecule
CDK5 cyclin-dependent kinase 5
CGN cingulin
CLTC clathrin, heavy chain (Hc)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYFIP1 cytoplasmic FMR1 interacting protein 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL2 dihydropyrimidinase-like 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ELP3 elongator acetyltransferase complex subunit 3
ENO2 enolase 2 (gamma, neuronal)
EPHA3 EPH receptor A3
EPRS glutamyl-prolyl-tRNA synthetase
ERBB2IP erbb2 interacting protein
FER fer (fps/fes related) tyrosine kinase
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PD glucose-6-phosphate dehydrogenase
GAB2 GRB2-associated binding protein 2
GDI2 GDP dissociation inhibitor 2
GOLGA5 golgin A5
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST2H2BE histone cluster 2, H2be
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA14 heat shock 70kDa protein 14
ITSN2 intersectin 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LY9 lymphocyte antigen 9
MTMR10 myotubularin related protein 10
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGM1 phosphoglucomutase 1
PHLDB3 pleckstrin homology-like domain, family B, member 3
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PKM pyruvate kinase, muscle
PKP4 plakophilin 4
PLCG1 phospholipase C, gamma 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAN RAN, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RPL4 ribosomal protein L4
SIT1 signaling threshold regulating transmembrane adaptor 1
SKAP1 src kinase associated phosphoprotein 1
TMIGD2 transmembrane and immunoglobulin domain containing 2
TRIM25 tripartite motif containing 25
TSG101 tumor susceptibility 101
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TXNRD1 thioredoxin reductase 1
UBASH3B ubiquitin associated and SH3 domain containing B
ZDHHC17 zinc finger, DHHC-type containing 17

decreased phosphorylation

Symbol Name
ACBD6 acyl-CoA binding domain containing 6
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ANXA11 annexin A11
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD5 CD5 molecule
CD7 CD7 molecule
CD82 CD82 molecule
DOK2 docking protein 2, 56kDa
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EIF3M eukaryotic translation initiation factor 3, subunit M
HIST4H4 histone cluster 4, H4
ITK IL2-inducible T-cell kinase
LAT linker for activation of T cells
MPZL1 myelin protein zero-like 1
MSL2 male-specific lethal 2 homolog (Drosophila)
OGN osteoglycin
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PTPRA protein tyrosine phosphatase, receptor type, A
SLAMF6 SLAM family member 6
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa