5z-7-oxozeaenol Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
Description A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB. (Chemical Entities of Biological Interest Ontology, CHEBI_67559)
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Genes

6 kinases inhibited by the 5z-7-oxozeaenol small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.18529
FLT3 fms-related tyrosine kinase 3 1.18186
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.08845
STK36 serine/threonine kinase 36 1.08004
FLT4 fms-related tyrosine kinase 4 1.06908
GAK cyclin G associated kinase 0.850157