6-azathymine-4106 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the 6-azathymine-4106 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHNAK2 AHNAK nucleoprotein 2
AIM1L absent in melanoma 1-like
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANGPT4 angiopoietin 4
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP24 Rho GTPase activating protein 24
ARRB1 arrestin, beta 1
ATF5 activating transcription factor 5
BANK1 B-cell scaffold protein with ankyrin repeats 1
BMP6 bone morphogenetic protein 6
C10ORF12 chromosome 10 open reading frame 12
C4BPA complement component 4 binding protein, alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC7 coiled-coil domain containing 7
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CELF2 CUGBP, Elav-like family member 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CRY2 cryptochrome circadian clock 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DES desmin
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EFNB3 ephrin-B3
ENO3 enolase 3 (beta, muscle)
FBLN1 fibulin 1
FGB fibrinogen beta chain
FRMD4A FERM domain containing 4A
FSHB follicle stimulating hormone, beta polypeptide
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GGT1 gamma-glutamyltransferase 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPM6A glycoprotein M6A
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H4E histone cluster 1, H4e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA10 homeobox A10
HOXA11 homeobox A11
HOXA7 homeobox A7
HOXB5 homeobox B5
HPX hemopexin
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IL2 interleukin 2
IL7R interleukin 7 receptor
INHBC inhibin, beta C
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KIAA0319 KIAA0319
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LDB3 LIM domain binding 3
LGALS8 lectin, galactoside-binding, soluble, 8
LMAN2 lectin, mannose-binding 2
LOXL3 lysyl oxidase-like 3
MAOB monoamine oxidase B
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NCOR2 nuclear receptor corepressor 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
OAZ3 ornithine decarboxylase antizyme 3
OMG oligodendrocyte myelin glycoprotein
OVOL1 ovo-like zinc finger 1
PCNX pecanex homolog (Drosophila)
PKNOX2 PBX/knotted 1 homeobox 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKCB protein kinase C, beta
RAD54L2 RAD54-like 2 (S. cerevisiae)
RND1 Rho family GTPase 1
RUNX1 runt-related transcription factor 1
SECTM1 secreted and transmembrane 1
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC35E2 solute carrier family 35, member E2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNED1 sushi, nidogen and EGF-like domains 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D22A TBC1 domain family, member 22A
TBC1D22B TBC1 domain family, member 22B
TBXA2R thromboxane A2 receptor
TENM4 teneurin transmembrane protein 4
TEX14 testis expressed 14
TFR2 transferrin receptor 2
TG thyroglobulin
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM144 transmembrane protein 144
TMEM206 transmembrane protein 206
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABI3BP ABI family, member 3 (NESH) binding protein
ACAD10 acyl-CoA dehydrogenase family, member 10
ALS2CL ALS2 C-terminal like
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB2 arrestin, beta 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAHCC1 BAH domain and coiled-coil containing 1
BFSP1 beaded filament structural protein 1, filensin
BMP4 bone morphogenetic protein 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C17ORF70 chromosome 17 open reading frame 70
CEL carboxyl ester lipase
CEMIP cell migration inducing protein, hyaluronan binding
CEP70 centrosomal protein 70kDa
CES3 carboxylesterase 3
COPZ2 coatomer protein complex, subunit zeta 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FLCN folliculin
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL1 guanine nucleotide binding protein-like 1
GPR157 G protein-coupled receptor 157
GRB7 growth factor receptor-bound protein 7
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IRF1 interferon regulatory factor 1
IRF7 interferon regulatory factor 7
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0894 KIAA0894 protein
LRRC61 leucine rich repeat containing 61
MYO19 myosin XIX
NAT6 N-acetyltransferase 6 (GCN5-related)
NLE1 notchless homolog 1 (Drosophila)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLIN3 perilipin 3
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
PRSS53 protease, serine, 53
PVRL3 poliovirus receptor-related 3
PYCR1 pyrroline-5-carboxylate reductase 1
QPCT glutaminyl-peptide cyclotransferase
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCAN3 RCAN family member 3
RECQL4 RecQ protein-like 4
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SP1 Sp1 transcription factor
STAB2 stabilin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TFF2 trefoil factor 2
TMEM159 transmembrane protein 159
TMEM19 transmembrane protein 19
TRIM16 tripartite motif containing 16
TSPYL2 TSPY-like 2
UBXN6 UBX domain protein 6
VIM vimentin
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF394 zinc finger protein 394
ZNF652 zinc finger protein 652