6-benzylaminopurine-4748 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 6-benzylaminopurine-4748 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACRV1 acrosomal vesicle protein 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACVR1B activin A receptor, type IB
ADAM8 ADAM metallopeptidase domain 8
AK1 adenylate kinase 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX15B arachidonate 15-lipoxygenase, type B
ANK1 ankyrin 1, erythrocytic
ARMC4 armadillo repeat containing 4
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP9B ATPase, class II, type 9B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GAT1 beta-1,3-glucuronyltransferase 1
BCL6 B-cell CLL/lymphoma 6
BST2 bone marrow stromal cell antigen 2
C22ORF46 chromosome 22 open reading frame 46
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CCKAR cholecystokinin A receptor
CCL27 chemokine (C-C motif) ligand 27
CD1C CD1c molecule
CDH8 cadherin 8, type 2
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEND1 cell cycle exit and neuronal differentiation 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRISP2 cysteine-rich secretory protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH4 cytohesin 4
DAAM2 dishevelled associated activator of morphogenesis 2
DAPK2 death-associated protein kinase 2
EMC3 ER membrane protein complex subunit 3
EMID1 EMI domain containing 1
ERC2-IT1 ERC2 intronic transcript 1
FGFR2 fibroblast growth factor receptor 2
GRIK5 glutamate receptor, ionotropic, kainate 5
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXD11 homeobox D11
IL12A interleukin 12A
IL1R2 interleukin 1 receptor, type II
INSL4 insulin-like 4 (placenta)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB8 integrin, beta 8
KCNIP2 Kv channel interacting protein 2
KHK ketohexokinase (fructokinase)
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LMTK1 lemur tail kinase 1
LOXL2 lysyl oxidase-like 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
NEK1 NIMA-related kinase 1
NEK9 NIMA-related kinase 9
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRP1 neuropilin 1
NRP2 neuropilin 2
NUDCD3 NudC domain containing 3
NXF2 nuclear RNA export factor 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDAP1 PDGFA associated protein 1
PDE5A phosphodiesterase 5A, cGMP-specific
PLVAP plasmalemma vesicle associated protein
POM121L2 POM121 transmembrane nucleoporin-like 2
POU2F2 POU class 2 homeobox 2
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRAMEF11 PRAME family member 11
PRKG2 protein kinase, cGMP-dependent, type II
PSCA prostate stem cell antigen
PTPRM protein tyrosine phosphatase, receptor type, M
RAB6A RAB6A, member RAS oncogene family
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RNF126P1 ring finger protein 126 pseudogene 1
RPL7 ribosomal protein L7
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA3P serum amyloid A3 pseudogene
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SSX1 synovial sarcoma, X breakpoint 1
TAL1 T-cell acute lymphocytic leukemia 1
TCF12 transcription factor 12
TFEB transcription factor EB
TLX2 T-cell leukemia homeobox 2
TMPRSS4 transmembrane protease, serine 4
TOX3 TOX high mobility group box family member 3
TREM1 triggering receptor expressed on myeloid cells 1
VIPR2 vasoactive intestinal peptide receptor 2
ZFP64 ZFP64 zinc finger protein
ZNF391 zinc finger protein 391
ZNF484 zinc finger protein 484
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAP2 ArfGAP with dual PH domains 2
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
ARC activity-regulated cytoskeleton-associated protein
B9D2 B9 protein domain 2
BAHD1 bromo adjacent homology domain containing 1
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPQ centromere protein Q
CHST10 carbohydrate sulfotransferase 10
CLSPN claspin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRY2 cryptochrome circadian clock 2
CST6 cystatin E/M
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOC2A double C2-like domains, alpha
DPY19L1P1 DPY19L1 pseudogene 1
EGFL7 EGF-like-domain, multiple 7
FADS2 fatty acid desaturase 2
FAM204A family with sequence similarity 204, member A
FER fer (fps/fes related) tyrosine kinase
FLCN folliculin
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HIST1H4F histone cluster 1, H4f
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
KCTD7 potassium channel tetramerization domain containing 7
KPTN kaptin (actin binding protein)
LGALS4 lectin, galactoside-binding, soluble, 4
LIG3 ligase III, DNA, ATP-dependent
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM4 MDM4, p53 regulator
MGC12488
MRPL44 mitochondrial ribosomal protein L44
MRPS18C mitochondrial ribosomal protein S18C
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OVOL1 ovo-like zinc finger 1
PAIP2B poly(A) binding protein interacting protein 2B
PBLD phenazine biosynthesis-like protein domain containing
PCDHGB5 protocadherin gamma subfamily B, 5
PER3 period circadian clock 3
PLA2G3 phospholipase A2, group III
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHOBTB2 Rho-related BTB domain containing 2
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TEP1 telomerase-associated protein 1
TESK1 testis-specific kinase 1
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TM7SF3 transmembrane 7 superfamily member 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TMEM38B transmembrane protein 38B
TRIM16 tripartite motif containing 16
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
VEZT vezatin, adherens junctions transmembrane protein
VLDLR very low density lipoprotein receptor
WDR76 WD repeat domain 76
ZNF219 zinc finger protein 219
ZNF286A zinc finger protein 286A
ZNF365 zinc finger protein 365
ZNF37BP zinc finger protein 37B, pseudogene
ZNF652 zinc finger protein 652