6-bromoindirubin-3'-oxime-6559 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the 6-bromoindirubin-3'-oxime-6559 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD26 ankyrin repeat domain 26
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APH1A APH1A gamma secretase subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB2 arrestin, beta 2
BAX BCL2-associated X protein
BIN1 bridging integrator 1
C3 complement component 3
CASKIN2 CASK interacting protein 2
CDC42 cell division cycle 42
CNTNAP2 contactin associated protein-like 2
CUL7 cullin 7
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
EYA4 EYA transcriptional coactivator and phosphatase 4
FYB FYN binding protein
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GOLGA2 golgin A2
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HMOX2 heme oxygenase 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGHMBP2 immunoglobulin mu binding protein 2
IQCC IQ motif containing C
KDM2A lysine (K)-specific demethylase 2A
KIFC1 kinesin family member C1
LAMC2 laminin, gamma 2
LMNB1 lamin B1
LOC157562 uncharacterized LOC157562
LONP2 lon peptidase 2, peroxisomal
MAP7 microtubule-associated protein 7
MED15 mediator complex subunit 15
MED25 mediator complex subunit 25
MFGE8 milk fat globule-EGF factor 8 protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRPL57 mitochondrial ribosomal protein L57
MTG1 mitochondrial ribosome-associated GTPase 1
MYL9 myosin, light chain 9, regulatory
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA3 nuclear receptor coactivator 3
NINJ1 ninjurin 1
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PADI2 peptidyl arginine deiminase, type II
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDH9 protocadherin 9
PDAP1 PDGFA associated protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF20L1 PHD finger protein 20-like 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRMT2 protein arginine methyltransferase 2
PRMT7 protein arginine methyltransferase 7
PTN pleiotrophin
RABIF RAB interacting factor
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBM38 RNA binding motif protein 38
RCAN3 RCAN family member 3
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS9 ribosomal protein S9
SBF1 SET binding factor 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMG7 SMG7 nonsense mediated mRNA decay factor
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SREK1IP1 SREK1-interacting protein 1
SRRM2 serine/arginine repetitive matrix 2
SSNA1 Sjogren syndrome nuclear autoantigen 1
SUGP2 SURP and G patch domain containing 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SURF1 surfeit 1
TAGLN3 transgelin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAZ tafazzin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TLE4 transducin-like enhancer of split 4
TMEM121 transmembrane protein 121
TMEM80 transmembrane protein 80
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TROVE2 TROVE domain family, member 2
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
WNK1 WNK lysine deficient protein kinase 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
AFAP1 actin filament associated protein 1
AKR1C3 aldo-keto reductase family 1, member C3
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEND5 BEN domain containing 5
C10ORF88 chromosome 10 open reading frame 88
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
C8ORF60 chromosome 8 open reading frame 60
CD34 CD34 molecule
CDK9 cyclin-dependent kinase 9
CES3 carboxylesterase 3
CINP cyclin-dependent kinase 2 interacting protein
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN1 claudin 1
COL9A2 collagen, type IX, alpha 2
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPA4 carboxypeptidase A4
CRLF3 cytokine receptor-like factor 3
CTC1 CTS telomere maintenance complex component 1
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND2D DENN/MADD domain containing 2D
DHRS11 dehydrogenase/reductase (SDR family) member 11
DPF3 D4, zinc and double PHD fingers, family 3
EFNA3 ephrin-A3
EHF ets homologous factor
EPN3 epsin 3
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESM1 endothelial cell-specific molecule 1
FAT4 FAT atypical cadherin 4
FEM1C fem-1 homolog c (C. elegans)
FGD1 FYVE, RhoGEF and PH domain containing 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FPGS folylpolyglutamate synthase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2AJ histone cluster 1, H2aj
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXB13 homeobox B13
IFI35 interferon-induced protein 35
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT81 intraflagellar transport 81
IL12A interleukin 12A
IMPACT impact RWD domain protein
JMJD4 jumonji domain containing 4
KPTN kaptin (actin binding protein)
LRRK1 leucine-rich repeat kinase 1
MCMBP minichromosome maintenance complex binding protein
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MOB3B MOB kinase activator 3B
MPDU1 mannose-P-dolichol utilization defect 1
NLK nemo-like kinase
NMD3 NMD3 ribosome export adaptor
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML2B olfactomedin-like 2B
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PBLD phenazine biosynthesis-like protein domain containing
PLAC8 placenta-specific 8
PLEKHO2 pleckstrin homology domain containing, family O member 2
POGK pogo transposable element with KRAB domain
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PSAT1 phosphoserine aminotransferase 1
PSKH1 protein serine kinase H1
RAB23 RAB23, member RAS oncogene family
RIPPLY3 ripply transcriptional repressor 3
RPL10L ribosomal protein L10-like
RUNX1-IT1 RUNX1 intronic transcript 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SFT2D2 SFT2 domain containing 2
SHROOM2 shroom family member 2
SLMO1 slowmo homolog 1 (Drosophila)
SSTR5 somatostatin receptor 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D19 TBC1 domain family, member 19
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEX30 testis expressed 30
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC26 tetratricopeptide repeat domain 26
TTF2 transcription termination factor, RNA polymerase II
TTPAL tocopherol (alpha) transfer protein-like
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB10 zinc finger and BTB domain containing 10
ZBTB38 zinc finger and BTB domain containing 38
ZNF230 zinc finger protein 230
ZNF665 zinc finger protein 665