| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the 6-bromoindirubin-3'-oxime-6589 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ATF2 | activating transcription factor 2 |
| ATP13A3 | ATPase type 13A3 |
| BAX | BCL2-associated X protein |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CES2 | carboxylesterase 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNTNAP2 | contactin associated protein-like 2 |
| COMMD4 | COMM domain containing 4 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| CUL9 | cullin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DLX2 | distal-less homeobox 2 |
| DUSP9 | dual specificity phosphatase 9 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FERMT1 | fermitin family member 1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HIRA | histone cell cycle regulator |
| HIST1H4C | histone cluster 1, H4c |
| HLA-F | major histocompatibility complex, class I, F |
| HPX | hemopexin |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL27RA | interleukin 27 receptor, alpha |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KRT17 | keratin 17, type I |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC644450 | uncharacterized LOC644450 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LUZP1 | leucine zipper protein 1 |
| MGC12488 | |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NEK11 | NIMA-related kinase 11 |
| NPEPPS | aminopeptidase puromycin sensitive |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUPL2 | nucleoporin like 2 |
| PCDH9 | protocadherin 9 |
| PCDHB13 | protocadherin beta 13 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRAMEF11 | PRAME family member 11 |
| PRMT7 | protein arginine methyltransferase 7 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB35 | RAB35, member RAS oncogene family |
| RBM5 | RNA binding motif protein 5 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN3 | Ras and Rab interactor 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPL23 | ribosomal protein L23 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SDC2 | syndecan 2 |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SFXN3 | sideroflexin 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| ST20 | suppressor of tumorigenicity 20 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STMN1 | stathmin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM121 | transmembrane protein 121 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAIP | TRAF interacting protein |
| TRMT61A | tRNA methyltransferase 61A |
| USP2 | ubiquitin specific peptidase 2 |
| VEGFB | vascular endothelial growth factor B |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF205 | zinc finger protein 205 |
| ZNF444 | zinc finger protein 444 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADCY6 | adenylate cyclase 6 |
| AIDA | axin interactor, dorsalization associated |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA2 | carbonic anhydrase II |
| CFD | complement factor D (adipsin) |
| CHML | choroideremia-like (Rab escort protein 2) |
| COQ6 | coenzyme Q6 monooxygenase |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCTN6 | dynactin 6 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHA2 | EPH receptor A2 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FADS2 | fatty acid desaturase 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAB2 | GRB2-associated binding protein 2 |
| GOLGA8B | golgin A8 family, member B |
| GRPR | gastrin-releasing peptide receptor |
| GTPBP2 | GTP binding protein 2 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BI | histone cluster 1, H2bi |
| HOXA4 | homeobox A4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| JAK2 | Janus kinase 2 |
| JOSD1 | Josephin domain containing 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM7A | lysine (K)-specific demethylase 7A |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MVD | mevalonate (diphospho) decarboxylase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PGR | progesterone receptor |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLAC1 | placenta-specific 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNB3 | plexin B3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PQLC2 | PQ loop repeat containing 2 |
| RAB5C | RAB5C, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RNF146 | ring finger protein 146 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| STK25 | serine/threonine kinase 25 |
| TMEM230 | transmembrane protein 230 |
| TMEM57 | transmembrane protein 57 |
| TNRC6B | trinucleotide repeat containing 6B |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| ULBP2 | UL16 binding protein 2 |
| WDR76 | WD repeat domain 76 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF134 | zinc finger protein 134 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF280D | zinc finger protein 280D |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF606 | zinc finger protein 606 |