6-bromoindirubin-3'-oxime-7044 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the 6-bromoindirubin-3'-oxime-7044 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
AEN apoptosis enhancing nuclease
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARTN artemin
ATP9A ATPase, class II, type 9A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTTN cortactin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAPK3 death-associated protein kinase 3
DEPDC5 DEP domain containing 5
DGAT1 diacylglycerol O-acyltransferase 1
DGKG diacylglycerol kinase, gamma 90kDa
DLX2 distal-less homeobox 2
DUSP2 dual specificity phosphatase 2
E2F4 E2F transcription factor 4, p107/p130-binding
EDC3 enhancer of mRNA decapping 3
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EIF3M eukaryotic translation initiation factor 3, subunit M
ELF4 E74-like factor 4 (ets domain transcription factor)
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EXOC5 exocyst complex component 5
FKBP1A FK506 binding protein 1A, 12kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
FXR2 fragile X mental retardation, autosomal homolog 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNS glucosamine (N-acetyl)-6-sulfatase
GSTM2 glutathione S-transferase mu 2 (muscle)
HFE hemochromatosis
HNMT histamine N-methyltransferase
HOMER3 homer scaffolding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
HSF1 heat shock transcription factor 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ITGB5 integrin, beta 5
KIAA0930 KIAA0930
KIF5C kinesin family member 5C
LDB1 LIM domain binding 1
LIG3 ligase III, DNA, ATP-dependent
LNPEP leucyl/cystinyl aminopeptidase
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
MCF2L MCF.2 cell line derived transforming sequence-like
MPI mannose phosphate isomerase
MTCP1 mature T-cell proliferation 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NBL1 neuroblastoma 1, DAN family BMP antagonist
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OVGP1 oviductal glycoprotein 1, 120kDa
PCGF3 polycomb group ring finger 3
PDE4DIP phosphodiesterase 4D interacting protein
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
PRMT2 protein arginine methyltransferase 2
PRR5 proline rich 5 (renal)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QKI QKI, KH domain containing, RNA binding
RAB35 RAB35, member RAS oncogene family
RCE1 Ras converting CAAX endopeptidase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPS28 ribosomal protein S28
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RSU1 Ras suppressor protein 1
SFSWAP splicing factor, suppressor of white-apricot family
SIM2 single-minded family bHLH transcription factor 2
SIX1 SIX homeobox 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMIM7 small integral membrane protein 7
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK38L serine/threonine kinase 38 like
TNS2 tensin 2
TRAFD1 TRAF-type zinc finger domain containing 1
TSC22D3 TSC22 domain family, member 3
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDHD1 WD repeat and HMG-box DNA binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF532 zinc finger protein 532
ZNF609 zinc finger protein 609
ZNF79 zinc finger protein 79
ZNF814 zinc finger protein 814
ZYX zyxin

decreased expression

Symbol Name
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACVR2A activin A receptor, type IIA
AGBL2 ATP/GTP binding protein-like 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMC6 armadillo repeat containing 6
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
CCDC57 coiled-coil domain containing 57
CD83 CD83 molecule
CFAP69 cilia and flagella associated protein 69
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTFR ciliary neurotrophic factor receptor
CRMP1 collapsin response mediator protein 1
CRYAB crystallin, alpha B
CT55 cancer/testis antigen 55
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DUSP13 dual specificity phosphatase 13
DYSF dysferlin
EGR3 early growth response 3
ELOVL4 ELOVL fatty acid elongase 4
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
ETNK2 ethanolamine kinase 2
F2R coagulation factor II (thrombin) receptor
FAM46C family with sequence similarity 46, member C
FBXL2 F-box and leucine-rich repeat protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FOXC1 forkhead box C1
FRK fyn-related Src family tyrosine kinase
FXYD5 FXYD domain containing ion transport regulator 5
GATA4 GATA binding protein 4
GPATCH2L G patch domain containing 2-like
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H4E histone cluster 1, H4e
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC8 homeobox C8
HRH2 histamine receptor H2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KREMEN2 kringle containing transmembrane protein 2
LECT1 leukocyte cell derived chemotaxin 1
LENEP lens epithelial protein
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBTPS2 membrane-bound transcription factor peptidase, site 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NELL2 NEL-like 2 (chicken)
NYNRIN NYN domain and retroviral integrase containing
OCM2 oncomodulin 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7A17 olfactory receptor, family 7, subfamily A, member 17
OSMR oncostatin M receptor
PCDHB13 protocadherin beta 13
PCDHB6 protocadherin beta 6
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLSCR4 phospholipid scramblase 4
PLXNB3 plexin B3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB30 RAB30, member RAS oncogene family
REEP4 receptor accessory protein 4
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RPA4 replication protein A4, 30kDa
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A8 solute carrier family 12, member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
STARD13 StAR-related lipid transfer (START) domain containing 13
TBC1D2 TBC1 domain family, member 2
TCP11L1 t-complex 11, testis-specific-like 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM40 transmembrane protein 40
TRAIP TRAF interacting protein
TRIM48 tripartite motif containing 48
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC30A tetratricopeptide repeat domain 30A
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
WDR91 WD repeat domain 91
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB44 zinc finger and BTB domain containing 44
ZNF134 zinc finger protein 134
ZNF862 zinc finger protein 862