| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/3157314 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in 6603-0104 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | 1.84 |
| ZG16B | zymogen granule protein 16B | 1.53 |
| KIZ | kizuna centrosomal protein | 0.95 |
| MCOLN2 | mucolipin 2 | 0.71 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.66 |
| CCDC112 | coiled-coil domain containing 112 | 0.52 |
| ALPK1 | alpha-kinase 1 | 0.51 |
| MSH5 | mutS homolog 5 | 0.49 |
| TIGD5 | tigger transposable element derived 5 | 0.49 |
| HAL | histidine ammonia-lyase | 0.48 |
| ZNF814 | zinc finger protein 814 | 0.47 |
| LINS1 | lines homolog 1 | 0.45 |
| TET3 | tet methylcytosine dioxygenase 3 | 0.44 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.44 |
| SFR1 | SWI5-dependent recombination repair 1 | 0.4 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.4 |
| SOX12 | SRY (sex determining region Y)-box 12 | 0.39 |
| PROSER3 | proline and serine rich 3 | 0.39 |
| METTL6 | methyltransferase like 6 | 0.39 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | 0.39 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.39 |
| FBXO44 | F-box protein 44 | 0.38 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | 0.37 |
| IL6ST | interleukin 6 signal transducer | 0.36 |
| FAM89A | family with sequence similarity 89, member A | 0.36 |
| EGR1 | early growth response 1 | 0.36 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.34 |
| FCHSD1 | FCH and double SH3 domains 1 | 0.34 |
| DERPC | DERPC proline and glycine rich nuclear protein | 0.34 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.34 |
| ZNF600 | zinc finger protein 600 | 0.34 |
| SMO | smoothened, frizzled class receptor | 0.33 |
| LRFN1 | leucine rich repeat and fibronectin type III domain containing 1 | 0.33 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.33 |
| KANK3 | KN motif and ankyrin repeat domains 3 | 0.33 |
| KRT222 | keratin 222, type II | 0.33 |
| B2M | beta-2-microglobulin | 0.33 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | 0.32 |
| S100A2 | S100 calcium binding protein A2 | 0.32 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.32 |
| GMCL2 | germ cell-less 2, spermatogenesis associated | 0.31 |
| PHETA1 | PH domain containing endocytic trafficking adaptor 1 | 0.31 |
| DCHS1 | dachsous cadherin-related 1 | 0.31 |
| IFFO2 | intermediate filament family orphan 2 | 0.31 |
| UBXN2A | UBX domain protein 2A | 0.31 |
| FAM234A | family with sequence similarity 234 member A | 0.31 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 0.31 |
| DEPDC7 | DEP domain containing 7 | 0.31 |
| NEU3 | sialidase 3 (membrane sialidase) | 0.31 |
| WDR5B | WD repeat domain 5B | 0.3 |
| SLC38A9 | solute carrier family 38, member 9 | 0.3 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.3 |
| H3C1 | H3 clustered histone 1 | 0.3 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.29 |
| DEAF1 | DEAF1 transcription factor | 0.29 |
| TCTN2 | tectonic family member 2 | 0.29 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.28 |
| DIXDC1 | DIX domain containing 1 | 0.28 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.28 |
| SH3BGRL2 | SH3 domain binding glutamate-rich protein like 2 | 0.28 |
| CMC4 | C-x(9)-C motif containing 4 | 0.28 |
| CDC42SE2 | CDC42 small effector 2 | 0.28 |
| PLD6 | phospholipase D family, member 6 | 0.28 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.28 |
| TULP4 | tubby like protein 4 | 0.28 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.28 |
| COA5 | cytochrome c oxidase assembly factor 5 | 0.28 |
| BAIAP2 | BAI1-associated protein 2 | 0.27 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.27 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.27 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.27 |
| SLX4IP | SLX4 interacting protein | 0.27 |
| KLHDC8B | kelch domain containing 8B | 0.27 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.27 |
| ZNF511 | zinc finger protein 511 | 0.27 |
| ZNF324 | zinc finger protein 324 | 0.27 |
| RNFT2 | ring finger protein, transmembrane 2 | 0.27 |
| CRELD1 | cysteine-rich with EGF-like domains 1 | 0.26 |
| HLA-F | major histocompatibility complex, class I, F | 0.26 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | 0.26 |
| ELL3 | elongation factor RNA polymerase II-like 3 | 0.26 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 0.26 |
| RNF166 | ring finger protein 166 | 0.26 |
| AUNIP | aurora kinase A and ninein interacting protein | 0.26 |
| ZNF35 | zinc finger protein 35 | 0.26 |
| ZNF697 | zinc finger protein 697 | 0.25 |
| PLA2G12A | phospholipase A2, group XIIA | 0.25 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.25 |
| HSF2 | heat shock transcription factor 2 | 0.25 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.25 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.25 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.25 |
| RCAN1 | regulator of calcineurin 1 | 0.25 |
| DUOX1 | dual oxidase 1 | 0.25 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.25 |
| SPATA20 | spermatogenesis associated 20 | 0.25 |
| PRKCH | protein kinase C, eta | 0.25 |
| GPATCH4 | G patch domain containing 4 | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MISP3 | MISP family member 3 | -1.08 |
| C7 | complement component 7 | -0.97 |
| AFAP1L1 | actin filament associated protein 1-like 1 | -0.67 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -0.64 |
| CCDC158 | coiled-coil domain containing 158 | -0.59 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.54 |
| MYH13 | myosin, heavy chain 13, skeletal muscle | -0.53 |
| METTL22 | methyltransferase like 22 | -0.53 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 | -0.52 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.51 |
| SRSF8 | serine/arginine-rich splicing factor 8 | -0.5 |
| RIOX1 | ribosomal oxygenase 1 | -0.47 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.45 |
| NMU | neuromedin U | -0.43 |
| GUCD1 | guanylyl cyclase domain containing 1 | -0.41 |
| LIME1 | Lck interacting transmembrane adaptor 1 | -0.41 |
| LDHD | lactate dehydrogenase D | -0.41 |
| TMEM41B | transmembrane protein 41B | -0.41 |
| ANTXR2 | anthrax toxin receptor 2 | -0.41 |
| ACTN4 | actinin, alpha 4 | -0.39 |
| TNS2 | tensin 2 | -0.38 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | -0.36 |
| TMC6 | transmembrane channel-like 6 | -0.36 |
| ZNF2 | zinc finger protein 2 | -0.36 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -0.34 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.33 |
| SCRN3 | secernin 3 | -0.33 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.33 |
| PRMT2 | protein arginine methyltransferase 2 | -0.33 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | -0.32 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.32 |
| C16ORF70 | chromosome 16 open reading frame 70 | -0.32 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.32 |
| RBP7 | retinol binding protein 7, cellular | -0.32 |
| SASH1 | SAM and SH3 domain containing 1 | -0.32 |
| SUCO | SUN domain containing ossification factor | -0.32 |
| GGACT | gamma-glutamylamine cyclotransferase | -0.31 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -0.31 |
| PAH | phenylalanine hydroxylase | -0.31 |
| ZNF653 | zinc finger protein 653 | -0.31 |
| AMOT | angiomotin | -0.3 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.3 |
| TPM4 | tropomyosin 4 | -0.3 |
| ADPRH | ADP-ribosylarginine hydrolase | -0.3 |
| ARSD | arylsulfatase D | -0.3 |
| TSPAN15 | tetraspanin 15 | -0.3 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) | -0.29 |
| PML | promyelocytic leukemia | -0.29 |
| KLK6 | kallikrein-related peptidase 6 | -0.29 |
| NHSL1 | NHS-like 1 | -0.29 |
| PKM | pyruvate kinase, muscle | -0.29 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.29 |
| FAM102A | family with sequence similarity 102, member A | -0.28 |
| TFR2 | transferrin receptor 2 | -0.28 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | -0.28 |
| EPHA4 | EPH receptor A4 | -0.28 |
| SP100 | SP100 nuclear antigen | -0.27 |
| ANKRD10 | ankyrin repeat domain 10 | -0.27 |
| PKHD1L1 | polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 | -0.27 |
| SLC25A44 | solute carrier family 25, member 44 | -0.26 |
| RPP21 | ribonuclease P/MRP 21kDa subunit | -0.26 |
| ALKBH6 | alkB, alkylation repair homolog 6 (E. coli) | -0.26 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.26 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.26 |
| ZNF544 | zinc finger protein 544 | -0.26 |
| FSTL1 | follistatin-like 1 | -0.25 |
| TANK | TRAF family member-associated NFKB activator | -0.25 |
| PEX26 | peroxisomal biogenesis factor 26 | -0.25 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.25 |
| TYSND1 | trypsin domain containing 1 | -0.25 |
| IP6K2 | inositol hexakisphosphate kinase 2 | -0.25 |
| HOMEZ | homeobox and leucine zipper encoding | -0.25 |
| CETN1 | centrin, EF-hand protein, 1 | -0.25 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.24 |
| ABHD4 | abhydrolase domain containing 4 | -0.24 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | -0.24 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.24 |
| CAV2 | caveolin 2 | -0.24 |
| FRMPD3 | FERM and PDZ domain containing 3 | -0.24 |
| TMEM51 | transmembrane protein 51 | -0.23 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.23 |
| TFAP2E | transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) | -0.23 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.23 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.23 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.23 |
| NFYB | nuclear transcription factor Y, beta | -0.23 |
| TMEM39A | transmembrane protein 39A | -0.23 |
| MYO3A | myosin IIIA | -0.23 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.22 |
| CD58 | CD58 molecule | -0.22 |
| CIC | capicua transcriptional repressor | -0.22 |
| MFSD8 | major facilitator superfamily domain containing 8 | -0.22 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.22 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | -0.22 |
| HDAC11 | histone deacetylase 11 | -0.22 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.22 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.22 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.22 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | -0.22 |
