697 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human B cell precursor leukemia; established from the bone marrow of a 12-year-old boy with acute lymphoblastic leukemia (cALL) at relapse in 1979. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001969)
Similar Terms
Downloads & Tools

Genes

272 genes mutated in the 697 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADGRB1 adhesion G protein-coupled receptor B1
ADGRG7 adhesion G protein-coupled receptor G7
ADGRV1 adhesion G protein-coupled receptor V1
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD11 ankyrin repeat domain 11
ANKRD39 ankyrin repeat domain 39
ANO5 anoctamin 5
ANXA13 annexin A13
APIP APAF1 interacting protein
ARHGAP9 Rho GTPase activating protein 9
ASCC1 activating signal cointegrator 1 complex subunit 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN1 ataxin 1
AVIL advillin
C1R complement component 1, r subcomponent
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CARD16 caspase recruitment domain family, member 16
CASZ1 castor zinc finger 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBS cystathionine-beta-synthase
CBX5 chromobox homolog 5
CCDC137 coiled-coil domain containing 137
CCHCR1 coiled-coil alpha-helical rod protein 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CEP104 centrosomal protein 104kDa
CEP290 centrosomal protein 290kDa
CFAP44 cilia and flagella associated protein 44
CHD2 chromodomain helicase DNA binding protein 2
CLASP2 cytoplasmic linker associated protein 2
CLCA1 chloride channel accessory 1
CLEC18B C-type lectin domain family 18, member B
CLSPN claspin
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTN3 contactin 3 (plasmacytoma associated)
COL11A2 collagen, type XI, alpha 2
COL2A1 collagen, type II, alpha 1
CRIPAK cysteine-rich PAK1 inhibitor
CRNKL1 crooked neck pre-mRNA splicing factor 1
CRYBB3 crystallin, beta B3
CSHL1 chorionic somatomammotropin hormone-like 1
CSPG4 chondroitin sulfate proteoglycan 4
CSRNP3 cysteine-serine-rich nuclear protein 3
CYB5RL cytochrome b5 reductase-like
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DCTN1 dynactin 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DNAAF1 dynein, axonemal, assembly factor 1
DNAH17 dynein, axonemal, heavy chain 17
DNAH5 dynein, axonemal, heavy chain 5
DNAH7 dynein, axonemal, heavy chain 7
DOCK2 dedicator of cytokinesis 2
DTX4 deltex 4, E3 ubiquitin ligase
EFNB1 ephrin-B1
ELAC2 elaC ribonuclease Z 2
ELN elastin
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA1 EPH receptor A1
EPHA3 EPH receptor A3
EPPK1 epiplakin 1
ETV6 ets variant 6
EVPLL envoplakin-like
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM131B family with sequence similarity 131, member B
FAM160B2 family with sequence similarity 160, member B2
FAM169B family with sequence similarity 169, member B
FAM171A1 family with sequence similarity 171, member A1
FANK1 fibronectin type III and ankyrin repeat domains 1
FAT1 FAT atypical cadherin 1
FBXW10 F-box and WD repeat domain containing 10
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF14 fibroblast growth factor 14
FLNB filamin B, beta
FRAS1 Fraser extracellular matrix complex subunit 1
FRY furry homolog (Drosophila)
FSCB fibrous sheath CABYR binding protein
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAGE1 G antigen 1
GAREM GRB2 associated, regulator of MAPK1
GAREML GRB2 associated, regulator of MAPK1-like
GGTLC2 gamma-glutamyltransferase light chain 2
GOSR1 golgi SNAP receptor complex member 1
GPATCH8 G patch domain containing 8
GPBP1 GC-rich promoter binding protein 1
GPR179 G protein-coupled receptor 179
GPR180 G protein-coupled receptor 180
GRAMD1C GRAM domain containing 1C
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSTM2 glutathione S-transferase mu 2 (muscle)
GTPBP4 GTP binding protein 4
H3F3A H3 histone, family 3A
HACL1 2-hydroxyacyl-CoA lyase 1
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HEATR5A HEAT repeat containing 5A
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HIST1H1A histone cluster 1, H1a
HLA-C major histocompatibility complex, class I, C
HOMER2 homer scaffolding protein 2
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSPA13 heat shock protein 70kDa family, member 13
IARS isoleucyl-tRNA synthetase
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA7 integrin, alpha 7
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNK18 potassium channel, two pore domain subfamily K, member 18
KDM6B lysine (K)-specific demethylase 6B
KIAA0100 KIAA0100
KIAA0232 KIAA0232
KIAA1467 KIAA1467
KIAA1522 KIAA1522
KIAA1671 KIAA1671
KIAA1841 KIAA1841
KIF15 kinesin family member 15
KIF5A kinesin family member 5A
KMT2D lysine (K)-specific methyltransferase 2D
KRT10 keratin 10, type I
KRTAP5-2 keratin associated protein 5-2
LEPR leptin receptor
LMBR1L limb development membrane protein 1-like
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC390956 peptidyl-prolyl cis-trans isomerase A pseudogene
LPAR3 lysophosphatidic acid receptor 3
LRRC63 leucine rich repeat containing 63
LSM1 LSM1, U6 small nuclear RNA associated
LYZL6 lysozyme-like 6
MAN2A1 mannosidase, alpha, class 2A, member 1
MANSC1 MANSC domain containing 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MIIP migration and invasion inhibitory protein
MTERF1 mitochondrial transcription termination factor 1
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MYO16 myosin XVI
MYO5B myosin VB
NAGLU N-acetylglucosaminidase, alpha
NBEA neurobeachin
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NEK10 NIMA-related kinase 10
NELL2 NEL-like 2 (chicken)
NKX3-1 NK3 homeobox 1
NOTCH3 notch 3
NOTCH4 notch 4
NPEPPS aminopeptidase puromycin sensitive
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5C2 5'-nucleotidase, cytosolic II
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OGDHL oxoglutarate dehydrogenase-like
OPRK1 opioid receptor, kappa 1
OR10P1 olfactory receptor, family 10, subfamily P, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR4K5 olfactory receptor, family 4, subfamily K, member 5
OSMR oncostatin M receptor
PARD3 par-3 family cell polarity regulator
PCDH17 protocadherin 17
PCDH19 protocadherin 19
PCDHA2 protocadherin alpha 2
PCDHGB2 protocadherin gamma subfamily B, 2
PCNX pecanex homolog (Drosophila)
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE4D phosphodiesterase 4D, cAMP-specific
PDIK1L PDLIM1 interacting kinase 1 like
PDZD3 PDZ domain containing 3
PHC2 polyhomeotic homolog 2 (Drosophila)
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PISD phosphatidylserine decarboxylase
PKN1 protein kinase N1
PLCB2 phospholipase C, beta 2
PLEC plectin
PLXNA2 plexin A2
PM20D1 peptidase M20 domain containing 1
POMT2 protein-O-mannosyltransferase 2
PPL periplakin
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCE protein kinase C, epsilon
PRKD2 protein kinase D2
PRSS1 protease, serine, 1 (trypsin 1)
PRTG protogenin
PSAP prosaposin
PSG2 pregnancy specific beta-1-glycoprotein 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RBM14 RNA binding motif protein 14
RELN reelin
REST RE1-silencing transcription factor
RINT1 RAD50 interactor 1
RLN1 relaxin 1
RMDN2 regulator of microtubule dynamics 2
RPAP1 RNA polymerase II associated protein 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RTTN rotatin
SCN5A sodium channel, voltage gated, type V alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SETD5 SET domain containing 5
SF3A2 splicing factor 3a, subunit 2, 66kDa
SH2B2 SH2B adaptor protein 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIMC1 SUMO-interacting motifs containing 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT7 sirtuin 7
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLIT1 slit homolog 1 (Drosophila)
SNX13 sorting nexin 13
SOAT1 sterol O-acyltransferase 1
SPRR2B small proline-rich protein 2B
STK3 serine/threonine kinase 3
STK36 serine/threonine kinase 36
STRA6 stimulated by retinoic acid 6
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SVIL supervillin
SYCP2L synaptonemal complex protein 2-like
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TATDN3 TatD DNase domain containing 3
TBX10 T-box 10
TCEA3 transcription elongation factor A (SII), 3
TCF20 transcription factor 20 (AR1)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLN2 talin 2
TLR9 toll-like receptor 9
TMEM115 transmembrane protein 115
TMEM87B transmembrane protein 87B
TMPRSS11B transmembrane protease, serine 11B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNIP1 TNFAIP3 interacting protein 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TPR translocated promoter region, nuclear basket protein
TRIM42 tripartite motif containing 42
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRRAP transformation/transcription domain-associated protein
TSSK3 testis-specific serine kinase 3
TTBK1 tau tubulin kinase 1
TTLL3 tubulin tyrosine ligase-like family member 3
TUBGCP6 tubulin, gamma complex associated protein 6
TXNRD1 thioredoxin reductase 1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UNC50 unc-50 homolog (C. elegans)
UNC5D unc-5 homolog D (C. elegans)
UNC79 unc-79 homolog (C. elegans)
USP30 ubiquitin specific peptidase 30
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VSIG1 V-set and immunoglobulin domain containing 1
WNT7A wingless-type MMTV integration site family, member 7A
ZC3H4 zinc finger CCCH-type containing 4
ZFC3H1 zinc finger, C3H1-type containing
ZFHX4 zinc finger homeobox 4
ZFYVE27 zinc finger, FYVE domain containing 27
ZNF208 zinc finger protein 208
ZNF446 zinc finger protein 446
ZNF462 zinc finger protein 462
ZNF525 zinc finger protein 525
ZNF783 zinc finger family member 783
ZNF84 zinc finger protein 84