7-aminocephalosporanic acid-3258 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the 7-aminocephalosporanic acid-3258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
ARC activity-regulated cytoskeleton-associated protein
ARHGAP4 Rho GTPase activating protein 4
BCR breakpoint cluster region
C1ORF54 chromosome 1 open reading frame 54
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD52 CD52 molecule
CDK14 cyclin-dependent kinase 14
CHKB choline kinase beta
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLGN calmegin
COL5A2 collagen, type V, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DFNB31 deafness, autosomal recessive 31
DMTN dematin actin binding protein
DOCK9 dedicator of cytokinesis 9
ECE1 endothelin converting enzyme 1
EGFL7 EGF-like-domain, multiple 7
EPYC epiphycan
FBXL2 F-box and leucine-rich repeat protein 2
FKBP8 FK506 binding protein 8, 38kDa
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSHB follicle stimulating hormone, beta polypeptide
GAB1 GRB2-associated binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GBP1 guanylate binding protein 1, interferon-inducible
GGT1 gamma-glutamyltransferase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR176 G protein-coupled receptor 176
GSTTP1 glutathione S-transferase theta pseudogene 1
H1F0 H1 histone family, member 0
HHLA1 HERV-H LTR-associating 1
HK2 hexokinase 2
HOMER3 homer scaffolding protein 3
ICOSLG inducible T-cell co-stimulator ligand
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
LPPR2 lipid phosphate phosphatase-related protein type 2
LSP1 lymphocyte-specific protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPK11 mitogen-activated protein kinase 11
MDM4 MDM4, p53 regulator
MOCS1 molybdenum cofactor synthesis 1
MST1 macrophage stimulating 1
NBEAL2 neurobeachin-like 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPM3 nucleophosmin/nucleoplasmin 3
NUCB1 nucleobindin 1
PAIP2B poly(A) binding protein interacting protein 2B
PALM paralemmin
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDAP1 PDGFA associated protein 1
PDCD2 programmed cell death 2
PEX5 peroxisomal biogenesis factor 5
PGAM2 phosphoglycerate mutase 2 (muscle)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLTP phospholipid transfer protein
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRS protein tyrosine phosphatase, receptor type, S
RASL11B RAS-like, family 11, member B
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHEB Ras homolog enriched in brain
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAND2P SCAN domain containing 2 pseudogene
SIAH1 siah E3 ubiquitin protein ligase 1
SIDT2 SID1 transmembrane family, member 2
SLC17A2 solute carrier family 17, member 2
SLC35E2 solute carrier family 35, member E2
SPTBN5 spectrin, beta, non-erythrocytic 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SREBF1 sterol regulatory element binding transcription factor 1
STK16 serine/threonine kinase 16
STK3 serine/threonine kinase 3
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TLE2 transducin-like enhancer of split 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TP53I11 tumor protein p53 inducible protein 11
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
UBOX5 U-box domain containing 5
YIPF4 Yip1 domain family, member 4
ZNF324 zinc finger protein 324
ZNF589 zinc finger protein 589
ZNF639 zinc finger protein 639
ZNF696 zinc finger protein 696
ZYX zyxin

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALPK1 alpha-kinase 1
ARRB1 arrestin, beta 1
ASB8 ankyrin repeat and SOCS box containing 8
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
BMP4 bone morphogenetic protein 4
C4ORF29 chromosome 4 open reading frame 29
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALCOCO1 calcium binding and coiled-coil domain 1
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CRYBB2P1 crystallin, beta B2 pseudogene 1
DCAF13 DDB1 and CUL4 associated factor 13
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFNA3 ephrin-A3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPPK1 epiplakin 1
ERCC2 excision repair cross-complementation group 2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FBXW12 F-box and WD repeat domain containing 12
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HIRA histone cell cycle regulator
HIST1H4A histone cluster 1, H4a
HIST1H4F histone cluster 1, H4f
HOOK1 hook microtubule-tethering protein 1
ITPKB inositol-trisphosphate 3-kinase B
KLK5 kallikrein-related peptidase 5
LYRM9 LYR motif containing 9
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
MTCL1 microtubule crosslinking factor 1
MVP major vault protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOD1 nucleotide-binding oligomerization domain containing 1
NPTX1 neuronal pentraxin I
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHA9 protocadherin alpha 9
PGBD5 piggyBac transposable element derived 5
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
PTK6 protein tyrosine kinase 6
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RWDD3 RWD domain containing 3
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SHARPIN SHANK-associated RH domain interactor
SIX1 SIX homeobox 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEX40 testis expressed 40
TH tyrosine hydroxylase
TIPRL TOR signaling pathway regulator
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TOM1 target of myb1 (chicken)
TPCN1 two pore segment channel 1
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
VASH1 vasohibin 1
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF350 zinc finger protein 350
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF701 zinc finger protein 701