7-aminocephalosporanic acid-4242 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the 7-aminocephalosporanic acid-4242 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AJAP1 adherens junctions associated protein 1
ANGPT1 angiopoietin 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP10A ATPase, class V, type 10A
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATXN7L1 ataxin 7-like 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BGN biglycan
BMP10 bone morphogenetic protein 10
C10ORF10 chromosome 10 open reading frame 10
CA5B carbonic anhydrase VB, mitochondrial
CEP41 centrosomal protein 41kDa
CLSTN3 calsyntenin 3
CLTA clathrin, light chain A
COL5A1 collagen, type V, alpha 1
COMT catechol-O-methyltransferase
CREBZF CREB/ATF bZIP transcription factor
CYTH4 cytohesin 4
DCN decorin
DCTN2 dynactin 2 (p50)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DTNA dystrobrevin, alpha
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
FAM49B family with sequence similarity 49, member B
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FHIT fragile histidine triad
FMNL1 formin-like 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GIMAP6 GTPase, IMAP family member 6
GLRA1 glycine receptor, alpha 1
GPRC5D G protein-coupled receptor, class C, group 5, member D
GZMK granzyme K (granzyme 3; tryptase II)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HFE hemochromatosis
ICOSLG inducible T-cell co-stimulator ligand
IGHM immunoglobulin heavy constant mu
IL36A interleukin 36, alpha
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KRT37 keratin 37, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
MAGEA12 melanoma antigen family A12
MCF2L MCF.2 cell line derived transforming sequence-like
MEFV Mediterranean fever
MORN1 MORN repeat containing 1
MSX2 msh homeobox 2
MTMR3 myotubularin related protein 3
MX2 MX dynamin-like GTPase 2
NCAN neurocan
NCF4 neutrophil cytosolic factor 4, 40kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDCD2 programmed cell death 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PKP4 plakophilin 4
PNMA3 paraneoplastic Ma antigen 3
PNPLA3 patatin-like phospholipase domain containing 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQLC2 PQ loop repeat containing 2
PRKG1 protein kinase, cGMP-dependent, type I
PTK2B protein tyrosine kinase 2 beta
RAVER2 ribonucleoprotein, PTB-binding 2
RHEB Ras homolog enriched in brain
RND1 Rho family GTPase 1
RPS14 ribosomal protein S14
RTN1 reticulon 1
SAFB scaffold attachment factor B
SCARF1 scavenger receptor class F, member 1
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD6 SMAD family member 6
SOCS3 suppressor of cytokine signaling 3
SULT4A1 sulfotransferase family 4A, member 1
TAL1 T-cell acute lymphocytic leukemia 1
TFCP2L1 transcription factor CP2-like 1
TGM2 transglutaminase 2
THBD thrombomodulin
TLK1 tousled-like kinase 1
TM6SF1 transmembrane 6 superfamily member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNIK TRAF2 and NCK interacting kinase
TNP2 transition protein 2 (during histone to protamine replacement)
TRIM29 tripartite motif containing 29
TSPAN32 tetraspanin 32
WDR55 WD repeat domain 55
WNT5B wingless-type MMTV integration site family, member 5B
WTAP Wilms tumor 1 associated protein
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
ALOX12 arachidonate 12-lipoxygenase
ANXA2P1 annexin A2 pseudogene 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AXIN1 axin 1
C14ORF105 chromosome 14 open reading frame 105
C22ORF46 chromosome 22 open reading frame 46
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCL2 chemokine (C-C motif) ligand 2
CD68 CD68 molecule
CD82 CD82 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CIDEB cell death-inducing DFFA-like effector b
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPNE7 copine VII
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXCL3 chemokine (C-X-C motif) ligand 3
CXORF21 chromosome X open reading frame 21
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF23 fibroblast growth factor 23
FRMPD1 FERM and PDZ domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GPR1 G protein-coupled receptor 1
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1T histone cluster 1, H1t
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
IL36RN interleukin 36 receptor antagonist
IQSEC2 IQ motif and Sec7 domain 2
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100287590 uncharacterized LOC100287590
LPAR4 lysophosphatidic acid receptor 4
LRRC61 leucine rich repeat containing 61
LTC4S leukotriene C4 synthase
MATN3 matrilin 3
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MTSS1L metastasis suppressor 1-like
MYL9 myosin, light chain 9, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NOTCH4 notch 4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
POMT2 protein-O-mannosyltransferase 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRM2 protamine 2
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RNF126P1 ring finger protein 126 pseudogene 1
S100A3 S100 calcium binding protein A3
SBNO2 strawberry notch homolog 2 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A6 solute carrier family 16, member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D22B TBC1 domain family, member 22B
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TLN1 talin 1
TMEM212 transmembrane protein 212
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
VEGFB vascular endothelial growth factor B
WNT1 wingless-type MMTV integration site family, member 1
ZFHX3 zinc finger homeobox 3
ZNF358 zinc finger protein 358
ZNF580 zinc finger protein 580
ZYX zyxin