7-aminocephalosporanic acid-4826 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the 7-aminocephalosporanic acid-4826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ACVR1B activin A receptor, type IB
ADARB1 adenosine deaminase, RNA-specific, B1
AFF2 AF4/FMR2 family, member 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARC activity-regulated cytoskeleton-associated protein
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL4C ADP-ribosylation factor-like 4C
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C22ORF46 chromosome 22 open reading frame 46
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAV3 caveolin 3
CCR7 chemokine (C-C motif) receptor 7
CD86 CD86 molecule
CDK13 cyclin-dependent kinase 13
CDRT1 CMT1A duplicated region transcript 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP45 cilia and flagella associated protein 45
CNOT4 CCR4-NOT transcription complex, subunit 4
COL13A1 collagen, type XIII, alpha 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYTH4 cytohesin 4
DCAF4 DDB1 and CUL4 associated factor 4
DFNA5 deafness, autosomal dominant 5
DOK2 docking protein 2, 56kDa
EDN1 endothelin 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF16 fibroblast growth factor 16
FGL1 fibrinogen-like 1
GPATCH2L G patch domain containing 2-like
GPR4 G protein-coupled receptor 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
H2AFX H2A histone family, member X
HBS1L HBS1-like translational GTPase
IRF4 interferon regulatory factor 4
IRF6 interferon regulatory factor 6
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KIAA1456 KIAA1456
MARK4 MAP/microtubule affinity-regulating kinase 4
MIER2 mesoderm induction early response 1, family member 2
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFX1 nuclear transcription factor, X-box binding 1
NMUR1 neuromedin U receptor 1
NOS1 nitric oxide synthase 1 (neuronal)
NPTX1 neuronal pentraxin I
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG2 neuregulin 2
PCDH1 protocadherin 1
PCDHB13 protocadherin beta 13
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF7 PHD finger protein 7
PIPOX pipecolic acid oxidase
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP5C protein phosphatase 5, catalytic subunit
PROX1 prospero homeobox 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
QKI QKI, KH domain containing, RNA binding
RABGAP1 RAB GTPase activating protein 1
RGS14 regulator of G-protein signaling 14
RGS20 regulator of G-protein signaling 20
RNF6 ring finger protein (C3H2C3 type) 6
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRAGB Ras-related GTP binding B
RUNX1 runt-related transcription factor 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SIK2 salt-inducible kinase 2
SIPA1 signal-induced proliferation-associated 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMAD6 SMAD family member 6
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTBN4 spectrin, beta, non-erythrocytic 4
TAPBPL TAP binding protein-like
TEX15 testis expressed 15
TMEM176A transmembrane protein 176A
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPP2 tripeptidyl peptidase II
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
TTC28 tetratricopeptide repeat domain 28
USP46 ubiquitin specific peptidase 46
WNK1 WNK lysine deficient protein kinase 1
WSCD1 WSC domain containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZNF112 zinc finger protein 112
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMDHD2 amidohydrolase domain containing 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATG9A autophagy related 9A
ATP13A2 ATPase type 13A2
ATXN2 ataxin 2
C5 complement component 5
CAPRIN2 caprin family member 2
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CENPT centromere protein T
CHPF chondroitin polymerizing factor
CIC capicua transcriptional repressor
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
CLEC16A C-type lectin domain family 16, member A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COQ6 coenzyme Q6 monooxygenase
CORO7 coronin 7
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYB561D2 cytochrome b561 family, member D2
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKZ diacylglycerol kinase, zeta
DOCK1 dedicator of cytokinesis 1
EFNA3 ephrin-A3
FAM189A2 family with sequence similarity 189, member A2
FBRS fibrosin
FKBP14 FK506 binding protein 14, 22 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GEMIN8 gem (nuclear organelle) associated protein 8
GLI3 GLI family zinc finger 3
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BJ histone cluster 1, H2bj
HOMER2 homer scaffolding protein 2
HOXC11 homeobox C11
HSPA2 heat shock 70kDa protein 2
IFT140 intraflagellar transport 140
INTS9 integrator complex subunit 9
KRI1 KRI1 homolog (S. cerevisiae)
LAMB3 laminin, beta 3
LIN37 lin-37 DREAM MuvB core complex component
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP5 low density lipoprotein receptor-related protein 5
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
NDRG4 NDRG family member 4
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NECAB3 N-terminal EF-hand calcium binding protein 3
NECAP2 NECAP endocytosis associated 2
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
PCSK7 proprotein convertase subtilisin/kexin type 7
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PHACTR4 phosphatase and actin regulator 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRAF2 PRA1 domain family, member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PTPRE protein tyrosine phosphatase, receptor type, E
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A4 S100 calcium binding protein A4
SDC3 syndecan 3
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1A SET domain containing 1A
SIRT6 sirtuin 6
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMG9 SMG9 nonsense mediated mRNA decay factor
SPAG4 sperm associated antigen 4
TAGLN transgelin
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D17 TBC1 domain family, member 17
TMEM109 transmembrane protein 109
TMEM51 transmembrane protein 51
TMEM53 transmembrane protein 53
TMEM62 transmembrane protein 62
TMEM8A transmembrane protein 8A
TRIP10 thyroid hormone receptor interactor 10
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3C tubulin, alpha 3c
TXLNA taxilin alpha
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF324 zinc finger protein 324