786O Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
Description Human renal cell adenocarcinoma cell line, established from a 58 years old caucasian male. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003781)
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Genes

382 gene knockdowns changing fitness of 786O relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
IL17C interleukin 17C 3.19303
LEFTY2 left-right determination factor 2 3.17549
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 3.16991
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 3.05188
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.7561
RBBP7 retinoblastoma binding protein 7 2.6506
BIRC5 baculoviral IAP repeat containing 5 2.62155
TSSK3 testis-specific serine kinase 3 2.49902
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.43212
SMC2 structural maintenance of chromosomes 2 2.32443
SDK1 sidekick cell adhesion molecule 1 2.29002
MOB4 MOB family member 4, phocein 2.28964
JOSD1 Josephin domain containing 1 2.18601
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.16812
EFHD1 EF-hand domain family, member D1 2.08801
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.93881
OVOL1 ovo-like zinc finger 1 1.9242
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.91053
GPR135 G protein-coupled receptor 135 1.90454
CHRD chordin 1.84848
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.84649
UBE2I ubiquitin-conjugating enzyme E2I 1.8337
ADGRE2 adhesion G protein-coupled receptor E2 1.82647
FOXD3 forkhead box D3 1.80491
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.78673
CPB1 carboxypeptidase B1 (tissue) 1.78595
TREML2 triggering receptor expressed on myeloid cells-like 2 1.76107
MKRN1 makorin ring finger protein 1 1.75965
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 1.75381
KIAA0195 KIAA0195 1.75161
HSPE1-MOB4 HSPE1-MOB4 readthrough 1.69763
TMEM209 transmembrane protein 209 1.64821
RYR2 ryanodine receptor 2 (cardiac) 1.64298
HNF1A HNF1 homeobox A 1.64273
TMEM33 transmembrane protein 33 1.63881
ATCAY ataxia, cerebellar, Cayman type 1.63428
DPP8 dipeptidyl-peptidase 8 1.60227
CEPT1 choline/ethanolamine phosphotransferase 1 1.5964
RGS18 regulator of G-protein signaling 18 1.59213
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.56951
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.56172
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 1.55449
NXF1 nuclear RNA export factor 1 1.54624
ATM ATM serine/threonine kinase 1.53697
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.52905
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.52901
POU4F3 POU class 4 homeobox 3 1.51185
TIGD6 tigger transposable element derived 6 1.51182
TRAIP TRAF interacting protein 1.50296
PC pyruvate carboxylase 1.50284
EPRS glutamyl-prolyl-tRNA synthetase 1.50075
EXOSC4 exosome component 4 1.49777
ABAT 4-aminobutyrate aminotransferase 1.49531
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.49354
MYO18A myosin XVIIIA 1.48687
C10ORF2 chromosome 10 open reading frame 2 1.4799
HIST1H4E histone cluster 1, H4e 1.47435
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 1.47081
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.46539
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.45561
TBP TATA box binding protein 1.45522
CHID1 chitinase domain containing 1 1.39954
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 1.39847
RHOV ras homolog family member V 1.39796
LRP1B low density lipoprotein receptor-related protein 1B 1.39393
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1.38842
MOCS3 molybdenum cofactor synthesis 3 1.38457
LOC442028 uncharacterized LOC442028 1.38101
TIMP3 TIMP metallopeptidase inhibitor 3 1.37942
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.3774
PURA purine-rich element binding protein A 1.37188
S100A10 S100 calcium binding protein A10 1.36882
MID1 midline 1 1.36413
SLC25A40 solute carrier family 25, member 40 1.36325
CBS cystathionine-beta-synthase 1.35607
CAB39 calcium binding protein 39 1.34999
TTK TTK protein kinase 1.34485
MDC1 mediator of DNA-damage checkpoint 1 1.34308
SLC30A7 solute carrier family 30 (zinc transporter), member 7 1.34202
GJA9-MYCBP GJA9-MYCBP readthrough 1.33903
PRDX6 peroxiredoxin 6 1.33767
TAS2R60 taste receptor, type 2, member 60 1.33587
KDM1A lysine (K)-specific demethylase 1A 1.32489
CLCA2 chloride channel accessory 2 1.32132
AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.3207
IL18R1 interleukin 18 receptor 1 1.31738
PHKB phosphorylase kinase, beta 1.31506
NRTN neurturin 1.31235
PDAP1 PDGFA associated protein 1 1.30313
IGF1R insulin-like growth factor 1 receptor 1.28805
FOXE3 forkhead box E3 1.28587
SGPP2 sphingosine-1-phosphate phosphatase 2 1.28342
TSLP thymic stromal lymphopoietin 1.2792
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 1.27857
SEC62 SEC62 homolog (S. cerevisiae) 1.27592
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 1.26741
USP20 ubiquitin specific peptidase 20 1.26677
TRIP10 thyroid hormone receptor interactor 10 1.26569
OR1N2 olfactory receptor, family 1, subfamily N, member 2 1.25961
KIF5B kinesin family member 5B 1.2587
KCNK10 potassium channel, two pore domain subfamily K, member 10 1.25708
PPIH peptidylprolyl isomerase H (cyclophilin H) 1.25314
PLA2G4B phospholipase A2, group IVB (cytosolic) 1.24976
TCF3 transcription factor 3 1.24508
CYBA cytochrome b-245, alpha polypeptide 1.23546
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.23292
STRN3 striatin, calmodulin binding protein 3 1.22855
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.22621
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 1.22323
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.21676
TCEAL1 transcription elongation factor A (SII)-like 1 1.20558
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 1.20268
GRK5 G protein-coupled receptor kinase 5 1.19156
IL17RC interleukin 17 receptor C 1.18352
RNF152 ring finger protein 152 1.1812
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.17784
BRI3 brain protein I3 1.17353
FBXO18 F-box protein, helicase, 18 1.17015
FMNL1 formin-like 1 1.16683
NME3 NME/NM23 nucleoside diphosphate kinase 3 1.16306
GUCA1A guanylate cyclase activator 1A (retina) 1.15982
ATF2 activating transcription factor 2 1.15285
REXO2 RNA exonuclease 2 1.15069
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.14595
ERP44 endoplasmic reticulum protein 44 1.14306
HLA-E major histocompatibility complex, class I, E 1.1424
ERBB2IP erbb2 interacting protein 1.14114
QRFPR pyroglutamylated RFamide peptide receptor 1.1377
METRN meteorin, glial cell differentiation regulator 1.1327
WWOX WW domain containing oxidoreductase 1.13264
COL4A2 collagen, type IV, alpha 2 1.12501
KRT85 keratin 85, type II 1.1239
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.12351
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.12296
IL13 interleukin 13 1.12213
NEUROG2 neurogenin 2 1.11648
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough 1.11515
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1 1.11101
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 1.1094
RNF144A ring finger protein 144A 1.10253
RPS4X ribosomal protein S4, X-linked 1.10099
C11ORF30 chromosome 11 open reading frame 30 1.10076
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.09888
GARS glycyl-tRNA synthetase 1.09737
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 1.09656
HOXC10 homeobox C10 1.08959
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.0864
NRIP1 nuclear receptor interacting protein 1 1.0863
TGFB2 transforming growth factor, beta 2 1.08555
PLS3 plastin 3 1.08238
LMNB1 lamin B1 1.07925
ARRB1 arrestin, beta 1 1.07727
RNPS1 RNA binding protein S1, serine-rich domain 1.07582
MRPS16 mitochondrial ribosomal protein S16 1.07248
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 1.07174
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.07033
DPP4 dipeptidyl-peptidase 4 1.06817
PEX5 peroxisomal biogenesis factor 5 1.06737
MMP8 matrix metallopeptidase 8 1.06694
PAN3 PAN3 poly(A) specific ribonuclease subunit 1.06674
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) 1.06139
ORM1 orosomucoid 1 1.06063
TEAD2 TEA domain family member 2 1.05964
KRTAP10-5 keratin associated protein 10-5 1.0569
CHML choroideremia-like (Rab escort protein 2) 1.0564
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 1.05629
SPRED2 sprouty-related, EVH1 domain containing 2 1.0559
BGLAP bone gamma-carboxyglutamate (gla) protein 1.05329
UBAC2 UBA domain containing 2 1.05211
GSR glutathione reductase 1.04931
MAP2K6 mitogen-activated protein kinase kinase 6 1.04919
ANXA8 annexin A8 1.04541
LAPTM4A lysosomal protein transmembrane 4 alpha 1.04185
GBX1 gastrulation brain homeobox 1 1.04098
MC5R melanocortin 5 receptor 1.03677
NOTCH2 notch 2 1.03212
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.03178
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 1.02959
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.02797
PPT2 palmitoyl-protein thioesterase 2 1.02703
EPHA5 EPH receptor A5 1.02691
ESRRA estrogen-related receptor alpha 1.02684
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 1.02516
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.02288
AGPS alkylglycerone phosphate synthase 1.02176
KLHL4 kelch-like family member 4 1.02018
TBX4 T-box 4 1.01811
HIST1H2AC histone cluster 1, H2ac 1.01572
ZNF222 zinc finger protein 222 1.01546
FKBP1A FK506 binding protein 1A, 12kDa 1.01438
RYK receptor-like tyrosine kinase 1.01386
ZNF382 zinc finger protein 382 1.00891
CCNI cyclin I 1.00874
INMT indolethylamine N-methyltransferase 1.00699
PLXNA1 plexin A1 1.00467
SOX30 SRY (sex determining region Y)-box 30 1.00138
GALE UDP-galactose-4-epimerase 1.00012

decreased fitness

Symbol Name Standardized Value
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -3.33094
ZNF77 zinc finger protein 77 -3.01706
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.90411
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.61882
HHEX hematopoietically expressed homeobox -2.41636
RYBP RING1 and YY1 binding protein -2.26664
RPS29 ribosomal protein S29 -2.24325
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.24219
EPAS1 endothelial PAS domain protein 1 -2.17281
TAS2R14 taste receptor, type 2, member 14 -2.14258
HMSD histocompatibility (minor) serpin domain containing -2.13663
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.11972
ZNF253 zinc finger protein 253 -2.11911
MTMR1 myotubularin related protein 1 -2.08267
THPO thrombopoietin -2.06498
CTRL chymotrypsin-like -2.04352
PRB4 proline-rich protein BstNI subfamily 4 -2.02156
TRIM25 tripartite motif containing 25 -1.96017
ZNF362 zinc finger protein 362 -1.95592
TLR5 toll-like receptor 5 -1.92946
SLC12A8 solute carrier family 12, member 8 -1.92398
ADAM29 ADAM metallopeptidase domain 29 -1.91892
RORA RAR-related orphan receptor A -1.89814
PZP pregnancy-zone protein -1.89359
SGPP1 sphingosine-1-phosphate phosphatase 1 -1.882
BAG4 BCL2-associated athanogene 4 -1.85053
IL17A interleukin 17A -1.84039
DICER1 dicer 1, ribonuclease type III -1.83759
ARNT aryl hydrocarbon receptor nuclear translocator -1.81445
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -1.77351
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.77111
ADAM23 ADAM metallopeptidase domain 23 -1.74274
ZNF479 zinc finger protein 479 -1.73102
IL9R interleukin 9 receptor -1.71172
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -1.64419
UBL4A ubiquitin-like 4A -1.63118
PTGES3 prostaglandin E synthase 3 (cytosolic) -1.6228
STAT5B signal transducer and activator of transcription 5B -1.61125
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 -1.60032
ZNF92 zinc finger protein 92 -1.58862
ADAM17 ADAM metallopeptidase domain 17 -1.56994
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.56794
PRSS55 protease, serine, 55 -1.55787
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -1.54235
FUS FUS RNA binding protein -1.49118
PRKCI protein kinase C, iota -1.48547
PRDM4 PR domain containing 4 -1.47923
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -1.46971
NR2E1 nuclear receptor subfamily 2, group E, member 1 -1.46233
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -1.44929
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.4291
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 -1.41901
HOXB4 homeobox B4 -1.41193
BMP2K BMP2 inducible kinase -1.4111
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -1.4036
TMC7 transmembrane channel-like 7 -1.39845
IRF8 interferon regulatory factor 8 -1.393
ACTN4 actinin, alpha 4 -1.39227
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.39017
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -1.38108
ETNK1 ethanolamine kinase 1 -1.38043
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -1.37846
RHPN2 rhophilin, Rho GTPase binding protein 2 -1.37491
ZNF257 zinc finger protein 257 -1.36955
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C -1.36632
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -1.3662
PHACTR3 phosphatase and actin regulator 3 -1.36574
ZNF138 zinc finger protein 138 -1.35955
ZIM2 zinc finger, imprinted 2 -1.35828
ADSSL1 adenylosuccinate synthase like 1 -1.34979
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -1.34684
TXNDC17 thioredoxin domain containing 17 -1.34372
FZD8 frizzled class receptor 8 -1.34362
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -1.34169
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.34121
ZNF680 zinc finger protein 680 -1.33634
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.33442
TMEM126B transmembrane protein 126B -1.32396
TBC1D2B TBC1 domain family, member 2B -1.30473
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -1.30359
SLC26A9 solute carrier family 26 (anion exchanger), member 9 -1.29905
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -1.28377
PAX8 paired box 8 -1.2803
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.27864
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 -1.27628
GIF gastric intrinsic factor (vitamin B synthesis) -1.27565
MMP27 matrix metallopeptidase 27 -1.26699
MCM3 minichromosome maintenance complex component 3 -1.26173
TRIM62 tripartite motif containing 62 -1.25645
FASN fatty acid synthase -1.25152
EIF3J eukaryotic translation initiation factor 3, subunit J -1.24548
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.23474
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.23188
RAB5B RAB5B, member RAS oncogene family -1.22947
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -1.22713
ARCN1 archain 1 -1.22591
ZNF493 zinc finger protein 493 -1.22386
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -1.22204
RCSD1 RCSD domain containing 1 -1.21783
MELK maternal embryonic leucine zipper kinase -1.21751
MAP7D1 MAP7 domain containing 1 -1.21732
PTEN phosphatase and tensin homolog -1.21249
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.21152
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -1.21119
ZRANB1 zinc finger, RAN-binding domain containing 1 -1.20678
ZNF45 zinc finger protein 45 -1.2063
UBE2F ubiquitin-conjugating enzyme E2F (putative) -1.20213
BRSK1 BR serine/threonine kinase 1 -1.20053
ADAMDEC1 ADAM-like, decysin 1 -1.19967
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 -1.19501
XYLB xylulokinase homolog (H. influenzae) -1.19377
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -1.18947
ZNF729 zinc finger protein 729 -1.18917
TOP1 topoisomerase (DNA) I -1.18798
CDH5 cadherin 5, type 2 (vascular endothelium) -1.18537
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -1.18337
MSL2 male-specific lethal 2 homolog (Drosophila) -1.18269
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -1.1738
VPREB1 pre-B lymphocyte 1 -1.16837
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -1.16606
TTF2 transcription termination factor, RNA polymerase II -1.16369
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -1.1634
SGK1 serum/glucocorticoid regulated kinase 1 -1.16263
TGM5 transglutaminase 5 -1.16225
ZNF554 zinc finger protein 554 -1.15614
RNASE4 ribonuclease, RNase A family, 4 -1.15498
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -1.14883
SPRY4 sprouty homolog 4 (Drosophila) -1.14741
CLCN1 chloride channel, voltage-sensitive 1 -1.14726
CLK2 CDC-like kinase 2 -1.1459
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.14073
IFNA14 interferon, alpha 14 -1.1376
FYN FYN proto-oncogene, Src family tyrosine kinase -1.12983
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -1.1275
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.12745
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -1.12492
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -1.12305
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -1.11939
CD79A CD79a molecule, immunoglobulin-associated alpha -1.11732
GZMM granzyme M (lymphocyte met-ase 1) -1.11584
OXSR1 oxidative stress responsive 1 -1.11434
PRCC papillary renal cell carcinoma (translocation-associated) -1.11303
CARD14 caspase recruitment domain family, member 14 -1.11285
KAT7 K(lysine) acetyltransferase 7 -1.11259
ALG10B ALG10B, alpha-1,2-glucosyltransferase -1.11225
TESK2 testis-specific kinase 2 -1.1097
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 -1.10387
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -1.1033
MAPK13 mitogen-activated protein kinase 13 -1.10258
EFHB EF-hand domain family, member B -1.09622
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.08531
TRIM54 tripartite motif containing 54 -1.08529
TNPO3 transportin 3 -1.07135
SAP30L SAP30-like -1.06923
PDCD6IP programmed cell death 6 interacting protein -1.06809
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) -1.06748
P3H2 prolyl 3-hydroxylase 2 -1.06727
NLN neurolysin (metallopeptidase M3 family) -1.06569
CLDN8 claudin 8 -1.06424
CHEK1 checkpoint kinase 1 -1.06096
ITGAV integrin, alpha V -1.05957
STIL SCL/TAL1 interrupting locus -1.05746
ACACB acetyl-CoA carboxylase beta -1.05539
ABHD16A abhydrolase domain containing 16A -1.05115
ZNF681 zinc finger protein 681 -1.04888
OR4D1 olfactory receptor, family 4, subfamily D, member 1 -1.04559
NCS1 neuronal calcium sensor 1 -1.04548
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -1.03809
GAL3ST4 galactose-3-O-sulfotransferase 4 -1.03365
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -1.03304
SEC23A Sec23 homolog A (S. cerevisiae) -1.03192
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -1.02992
AADAC arylacetamide deacetylase -1.02449
NRBP1 nuclear receptor binding protein 1 -1.0227
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -1.01691
ATP11A ATPase, class VI, type 11A -1.0158
FDPS farnesyl diphosphate synthase -1.01569
ZNF324 zinc finger protein 324 -1.01281
ZNF737 zinc finger protein 737 -1.01103
KARS lysyl-tRNA synthetase -1.00757
RC3H2 ring finger and CCCH-type domains 2 -1.00708
CHN1 chimerin 1 -1.00708
RAB31 RAB31, member RAS oncogene family -1.00624
U2AF2 U2 small nuclear RNA auxiliary factor 2 -1.00547
ARHGAP24 Rho GTPase activating protein 24 -1.00478