786O Gene Set

Dataset CCLE Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human renal cell adenocarcinoma cell line, established from a 58 years old caucasian male. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003781)
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Genes

290 genes with high or low copy number in 786O relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
ARHGAP6 Rho GTPase activating protein 6 2.21496
UPK3B uroplakin 3B 1.87504
BOK BCL2-related ovarian killer 1.82821
DDX11L10 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 10 1.76378
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 1.7182
DAZ1 deleted in azoospermia 1 1.69824
CCND2 cyclin D2 1.59947
CAMTA1 calmodulin binding transcription activator 1 1.59154
PRSS46 protease, serine, 46 1.5544
RPS4Y2 ribosomal protein S4, Y-linked 2 1.5409
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding) 1.54046
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.54046
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene 1.52014
TTTY5 testis-specific transcript, Y-linked 5 (non-protein coding) 1.52014
RBMY2EP RNA binding motif protein, Y-linked, family 2, member E pseudogene 1.51745
TTTY13 testis-specific transcript, Y-linked 13 (non-protein coding) 1.50998
LINC01106 long intergenic non-protein coding RNA 1106 1.50997
DAZ2 deleted in azoospermia 2 1.50432
KDM5D lysine (K)-specific demethylase 5D 1.46207
TXLNGY taxilin gamma pseudogene, Y-linked 1.46137
BCORP1 BCL6 corepressor pseudogene 1 1.46137
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding) 1.45987
BOK-AS1 BOK antisense RNA 1 1.45077
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 1.43498
USP9Y ubiquitin specific peptidase 9, Y-linked 1.43468
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.43394
GYG2P1 glycogenin 2 pseudogene 1 1.42961
TSPY1 testis specific protein, Y-linked 1 1.42813
TSPY8 testis specific protein, Y-linked 8 1.42813
FAM197Y5 family with sequence similarity 197, Y-linked, member 5, pseudogene 1.42674
FAM197Y2 family with sequence similarity 197, Y-linked, member 2, pseudogene 1.42674
TSPY4 testis specific protein, Y-linked 4 1.42525
TSPY3 testis specific protein, Y-linked 3 1.42525
TMSB4Y thymosin beta 4, Y-linked 1.41903
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.41861
NLGN4Y-AS1 NLGN4Y antisense RNA 1 1.40951
NLGN4Y neuroligin 4, Y-linked 1.40951
TTTY20 testis-specific transcript, Y-linked 20 (non-protein coding) 1.40162
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) 1.39995
PRKY protein kinase, Y-linked, pseudogene 1.39972
AMELY amelogenin, Y-linked 1.38075
TBL1Y transducin (beta)-like 1, Y-linked 1.38056
RBMY1A3P RNA binding motif protein, Y-linked, family 1, member A3 pseudogene 1.36401
TTTY16 testis-specific transcript, Y-linked 16 (non-protein coding) 1.36318
TTTY12 testis-specific transcript, Y-linked 12 (non-protein coding) 1.3624
TTTY18 testis-specific transcript, Y-linked 18 (non-protein coding) 1.35698
TTTY11 testis-specific transcript, Y-linked 11 (non-protein coding) 1.35635
RBMY3AP RNA binding motif protein, Y-linked, family 3, member A pseudogene 1.35488
TTTY19 testis-specific transcript, Y-linked 19 (non-protein coding) 1.35455
PCDH11Y protocadherin 11 Y-linked 1.35417

low copy number

Symbol Name Standardized Value
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -3.21049
GLRA2 glycine receptor, alpha 2 -3.21049
DUX4L4 double homeobox 4 like 4 -3.00711
DAAM1 dishevelled associated activator of morphogenesis 1 -2.81225
FRG2 FSHD region gene 2 -2.81042
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -2.59447
HIF1A-AS2 HIF1A antisense RNA 2 -2.59387
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -2.37928
ATL1 atlastin GTPase 1 -2.35208
IP6K3 inositol hexakisphosphate kinase 3 -2.3514
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -2.3512
CHERP calcium homeostasis endoplasmic reticulum protein -2.29344
FRY furry homolog (Drosophila) -2.2047
SAV1 salvador family WW domain containing protein 1 -2.20347
CTSO cathepsin O -2.18773
SMIM7 small integral membrane protein 7 -2.16937
LOC389247 uncharacterized LOC389247 -2.15122
ING2 inhibitor of growth family, member 2 -2.15122
CLDN22 claudin 22 -2.14774
CLDN24 claudin 24 -2.14774
WWC2 WW and C2 domain containing 2 -2.1473
WWC2-AS2 WWC2 antisense RNA 2 -2.14708
FAM92A1P2 family with sequence similarity 92, member A3 -2.14708
CDKN2AIP CDKN2A interacting protein -2.14694
FRG1 FSHD region gene 1 -2.10315
AGA aspartylglucosaminidase -2.08751
CFAP97 cilia and flagella associated protein 97 -2.07848
TRAPPC11 trafficking protein particle complex 11 -2.05538
RWDD4 RWD domain containing 4 -2.05525
OR2T27 olfactory receptor, family 2, subfamily T, member 27 -2.04851
LOC728175 uncharacterized LOC728175 -2.03637
LRP2BP LRP2 binding protein -1.99642
ANKRD37 ankyrin repeat domain 37 -1.99642
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -1.99209
CCDC110 coiled-coil domain containing 110 -1.99147
UFSP2 UFM1-specific peptidase 2 -1.99147
C4ORF47 chromosome 4 open reading frame 47 -1.99147
SNX25 sorting nexin 25 -1.99083
TMEM38A transmembrane protein 38A -1.98412
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -1.95824
LOC100294145 uncharacterized LOC100294145 -1.93144
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -1.92892
PDLIM3 PDZ and LIM domain 3 -1.91873
HSP90AA4P heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene -1.90016
SLC35E1 solute carrier family 35, member E1 -1.88209
LOC728554 THO complex 3 pseudogene -1.87078
GRIK2 glutamate receptor, ionotropic, kainate 2 -1.86413
STOX2 storkhead box 2 -1.84219
MGC45800 -1.80197
MIR1305 microRNA 1305 -1.80197
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.78948
FLJ38576 uncharacterized LOC651430 -1.76108
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 -1.76095
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -1.76095
TLR3 toll-like receptor 3 -1.75495
BNC2 basonuclin 2 -1.74583
NEIL3 nei endonuclease VIII-like 3 (E. coli) -1.73174
ZFP42 ZFP42 zinc finger protein -1.71509
MTNR1A melatonin receptor 1A -1.71505
TRIML2 tripartite motif family-like 2 -1.71487
HELT helt bHLH transcription factor -1.70682
F11 coagulation factor XI -1.67738
F11-AS1 F11 antisense RNA 1 -1.66811
FAM21C family with sequence similarity 21, member C -1.66521
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -1.66521
DCTD dCMP deaminase -1.65972
LOC339975 uncharacterized LOC339975 -1.64937
TRIML1 tripartite motif family-like 1 -1.64144
DPY19L2P1 DPY19L2 pseudogene 1 -1.62425
BTF3 basic transcription factor 3 -1.61219
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) -1.61219
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -1.61219
FOXD1 forkhead box D1 -1.61142
TMEM174 transmembrane protein 174 -1.61142
CNTN3 contactin 3 (plasmacytoma associated) -1.61114
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.59772
RNF103-CHMP3 RNF103-CHMP3 readthrough -1.5976
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 -1.59294
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.59294
HEXB hexosaminidase B (beta polypeptide) -1.5927
IRF2 interferon regulatory factor 2 -1.59073
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -1.58928
TBC1D3H TBC1 domain family, member 3H -1.58889
TMEM171 transmembrane protein 171 -1.5807
MIR4804 microRNA 4804 -1.58043
MIR4803 microRNA 4803 -1.57889
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene -1.57581
ZCCHC9 zinc finger, CCHC domain containing 9 -1.57328
CARTPT CART prepropeptide -1.57141
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 -1.56397
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.56256
GFM2 G elongation factor, mitochondrial 2 -1.56256
MAP1B microtubule-associated protein 1B -1.55299
TNPO1 transportin 1 -1.55089
PTCD2 pentatricopeptide repeat domain 2 -1.54967
MRPS27 mitochondrial ribosomal protein S27 -1.5496
FAM151B family with sequence similarity 151, member B -1.54935
LINC00910 long intergenic non-protein coding RNA 910 -1.54917
DHFR dihydrofolate reductase -1.54899
MTRNR2L2 MT-RNR2-like 2 -1.54899
RPS23 ribosomal protein S23 -1.54795
SORBS2 sorbin and SH3 domain containing 2 -1.5419
ZBED3 zinc finger, BED-type containing 3 -1.53732
CRHBP corticotropin releasing hormone binding protein -1.53732
SNORA47 small nucleolar RNA, H/ACA box 47 -1.53732
AGGF1 angiogenic factor with G patch and FHA domains 1 -1.53732
S100Z S100 calcium binding protein Z -1.53723
FAM169A family with sequence similarity 169, member A -1.53425
F2R coagulation factor II (thrombin) receptor -1.53342
NCRUPAR non-protein coding RNA, upstream of F2R/PAR1 -1.53342
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -1.53186
OTP orthopedia homeobox -1.53014
DMGDH dimethylglycine dehydrogenase -1.52827
BHMT2 betaine--homocysteine S-methyltransferase 2 -1.52827
BHMT betaine--homocysteine S-methyltransferase -1.52827
MIR5003 microRNA 5003 -1.52827
POLK polymerase (DNA directed) kappa -1.52795
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -1.52794
POC5 POC5 centriolar protein -1.52789
F2RL2 coagulation factor II (thrombin) receptor-like 2 -1.52463
CMYA5 cardiomyopathy associated 5 -1.52372
PAPD4 PAP associated domain containing 4 -1.5236
FCHO2 FCH domain only 2 -1.52326
ANKRD34B ankyrin repeat domain 34B -1.52244
JMY junction mediating and regulatory protein, p53 cofactor -1.52172
LOC644936 actin, beta pseudogene -1.52153
SPZ1 spermatogenic leucine zipper 1 -1.52121
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like -1.52052
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -1.52019
SCARNA18 small Cajal body-specific RNA 18 -1.51843
MIR3977 microRNA 3977 -1.51843
WDR41 WD repeat domain 41 -1.50342
ACOT12 acyl-CoA thioesterase 12 -1.49854
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -1.49786
ZFYVE16 zinc finger, FYVE domain containing 16 -1.49569
MSH3 mutS homolog 3 -1.49495
THBS4 thrombospondin 4 -1.49403
TMEM167A transmembrane protein 167A -1.49253
ZBED3-AS1 ZBED3 antisense RNA 1 -1.49015
NFIB nuclear factor I/B -1.4882
TBCA tubulin folding cofactor A -1.47822
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.47734
SCAMP1 secretory carrier membrane protein 1 -1.47611
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -1.47307
MRPS36 mitochondrial ribosomal protein S36 -1.47212
CDK7 cyclin-dependent kinase 7 -1.47194
CCDC125 coiled-coil domain containing 125 -1.47191
CENPH centromere protein H -1.47187
CCNB1 cyclin B1 -1.4718
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -1.4718
MTX3 metaxin 3 -1.46943
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -1.45788
F2RL1 coagulation factor II (thrombin) receptor-like 1 -1.45771
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -1.45381
OTUD4 OTU deubiquitinase 4 -1.45066
ZNF366 zinc finger protein 366 -1.44972
HOMER1 homer scaffolding protein 1 -1.44873
MARVELD2 MARVEL domain containing 2 -1.44825
RAD17 RAD17 homolog (S. pombe) -1.44815
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -1.43786
LINC01098 long intergenic non-protein coding RNA 1098 -1.4372
ANKRD31 ankyrin repeat domain 31 -1.43536
CKMT2-AS1 CKMT2 antisense RNA 1 -1.43126
ANAPC10 anaphase promoting complex subunit 10 -1.43106
LHFPL2 lipoma HMGIC fusion partner-like 2 -1.42961
SMAD1 SMAD family member 1 -1.42787
FAM157A family with sequence similarity 157, member A -1.42427
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.4222
NKAIN2 Na+/K+ transporting ATPase interacting 2 -1.41901
CD180 CD180 molecule -1.41866
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -1.40891
CRSP8P mediator complex subunit 27 pseudogene -1.40452
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -1.40267
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -1.40006
TTC23 tetratricopeptide repeat domain 23 -1.39947
EPHA3 EPH receptor A3 -1.39935
NBPF22P neuroblastoma breakpoint family, member 22, pseudogene -1.39651
SREK1IP1 SREK1-interacting protein 1 -1.38779
FAM159B family with sequence similarity 159, member B -1.38701
LINC01095 long intergenic non-protein coding RNA 1095 -1.3863
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.38525
MIR583 microRNA 583 -1.38483
LRRC28 leucine rich repeat containing 28 -1.38205
NLN neurolysin (metallopeptidase M3 family) -1.38188
EDIL3 EGF-like repeats and discoidin I-like domains 3 -1.38181
CENPK centromere protein K -1.37806
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -1.3779
MIR3607 microRNA 3607 -1.37712
COX7C cytochrome c oxidase subunit VIIc -1.37712
CCNH cyclin H -1.37703
LOC100303749 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) pseudogene -1.37639
TRAPPC13 trafficking protein particle complex 13 -1.37618
TRIM23 tripartite motif containing 23 -1.37618
POU4F2 POU class 4 homeobox 2 -1.37587
AP3B1 adaptor-related protein complex 3, beta 1 subunit -1.37575
RGS7BP regulator of G-protein signaling 7 binding protein -1.37396
SSBP2 single-stranded DNA binding protein 2 -1.37343
SDK1 sidekick cell adhesion molecule 1 -1.36996
PCSK1 proprotein convertase subtilisin/kexin type 1 -1.36971
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -1.36926
MIR4280 microRNA 4280 -1.36808
LINC01554 long intergenic non-protein coding RNA 1554 -1.36783
GPR150 G protein-coupled receptor 150 -1.36777
RFESD Rieske (Fe-S) domain containing -1.36777
SPATA9 spermatogenesis associated 9 -1.36777
ARSK arylsulfatase family, member K -1.36772
RHOBTB3 Rho-related BTB domain containing 3 -1.36772
GLRX glutaredoxin (thioltransferase) -1.36772
LOC100133050 glucuronidase, beta pseudogene -1.36679
SERINC5 serine incorporator 5 -1.36662
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -1.36635
TMEM161B-AS1 TMEM161B antisense RNA 1 -1.36195
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta -1.3578
MIR548F3 microRNA 548f-3 -1.35623
NMU neuromedin U -1.35448
KIF2A kinesin heavy chain member 2A -1.35123
LIX1 Lix1 homolog (chicken) -1.34994
LOC642366 uncharacterized LOC642366 -1.34957
ISL1 ISL LIM homeobox 1 -1.34949
FAM174A family with sequence similarity 174, member A -1.34881
RGMB-AS1 RGMB antisense RNA 1 -1.34864
RGMB repulsive guidance molecule family member b -1.34864
MIR9-2 microRNA 9-2 -1.34688
LINC00461 long intergenic non-protein coding RNA 461 -1.34685
ERAP1 endoplasmic reticulum aminopeptidase 1 -1.3444
GAPT GRB2-binding adaptor protein, transmembrane -1.3384
PLK2 polo-like kinase 2 -1.33821
ERBB2IP erbb2 interacting protein -1.33788
TTC29 tetratricopeptide repeat domain 29 -1.3373
TTC37 tetratricopeptide repeat domain 37 -1.33671
LNPEP leucyl/cystinyl aminopeptidase -1.33499
LRRC70 leucine rich repeat containing 70 -1.33401
LOC100289230 uncharacterized LOC100289230 -1.33289
RIOK2 RIO kinase 2 -1.33254
MIR3660 microRNA 3660 -1.3322
FAM81B family with sequence similarity 81, member B -1.33215
RNF180 ring finger protein 180 -1.33171
TBC1D3C TBC1 domain family, member 3C -1.32945
PARP8 poly (ADP-ribose) polymerase family, member 8 -1.32725
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -1.32374