| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 8-Hydroxyquinoline_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.107729 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0915659 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.068376 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0590546 |
| COL5A1 | collagen, type V, alpha 1 | 0.0571333 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0564407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0547898 |
| DST | dystonin | 0.0541285 |
| COL5A2 | collagen, type V, alpha 2 | 0.04858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451527 |
| NAV1 | neuron navigator 1 | 0.0443648 |
| PLEC | plectin | 0.0412176 |
| APP | amyloid beta (A4) precursor protein | 0.0410587 |
| CDH13 | cadherin 13 | 0.0377498 |
| LDHA | lactate dehydrogenase A | 0.0369892 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355635 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0355434 |
| EGFR | epidermal growth factor receptor | 0.0332772 |
| MYOF | myoferlin | 0.0324582 |
| PKM | pyruvate kinase, muscle | 0.0320046 |
| SEPTIN9 | septin 9 | 0.0314816 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314729 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0299801 |
| CANX | calnexin | 0.0290326 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287167 |
| FBN1 | fibrillin 1 | 0.0283129 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0278591 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0275346 |
| GLIS3 | GLIS family zinc finger 3 | 0.0274008 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.027072 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0259729 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0259112 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250728 |
| TPM3 | tropomyosin 3 | 0.0247004 |
| LOXL2 | lysyl oxidase-like 2 | 0.0244674 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.023519 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0231938 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.022844 |
| THBS2 | thrombospondin 2 | 0.0217201 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0216247 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0204271 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0203075 |
| RUNX1 | runt-related transcription factor 1 | 0.0201659 |
| ASPH | aspartate beta-hydroxylase | 0.0200853 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0196515 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0195629 |
| ATP13A3 | ATPase type 13A3 | 0.019295 |
| ANXA2 | annexin A2 | 0.0192083 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0189446 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0188403 |
| AUTS2 | autism susceptibility candidate 2 | 0.0188161 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187819 |
| DSPP | dentin sialophosphoprotein | 0.0185692 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0184006 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0183349 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0182675 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0182316 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0181854 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0180938 |
| FLNB | filamin B, beta | 0.0180631 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0177576 |
| COL3A1 | collagen, type III, alpha 1 | 0.0176757 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0176301 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0175294 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0172165 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0170831 |
| LOX | lysyl oxidase | 0.016643 |
| VEGFC | vascular endothelial growth factor C | 0.0166401 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0164703 |
| MB21D2 | Mab-21 domain containing 2 | 0.0162668 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0162455 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0162004 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.016174 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0160793 |
| COPA | coatomer protein complex, subunit alpha | 0.0160723 |
| NEK7 | NIMA-related kinase 7 | 0.0159255 |
| NAV2 | neuron navigator 2 | 0.015912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.015897 |
| FLNA | filamin A, alpha | 0.0158838 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0158828 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0158665 |
| SBF2 | SET binding factor 2 | 0.015766 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0157643 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0154157 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0153204 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0153179 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0152691 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0151482 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0147611 |
| SLFN5 | schlafen family member 5 | 0.0147403 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0146977 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0144507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0143832 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0143614 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.01434 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0142863 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0142166 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0141792 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0141381 |
| RAI14 | retinoic acid induced 14 | 0.0140849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.213834 |
| VIM | vimentin | -0.148273 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.135233 |
| MT2A | metallothionein 2A | -0.113764 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10455 |
| PTMA | prothymosin, alpha | -0.0618875 |
| PLAT | plasminogen activator, tissue | -0.0545221 |
| SUCNR1 | succinate receptor 1 | -0.0492156 |
| S100A10 | S100 calcium binding protein A10 | -0.045103 |
| CSTB | cystatin B (stefin B) | -0.0446522 |
| NDRG1 | N-myc downstream regulated 1 | -0.0439339 |
| HLA-B | major histocompatibility complex, class I, B | -0.0436368 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404463 |
| B2M | beta-2-microglobulin | -0.0397056 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0375517 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0357514 |
| RPL35A | ribosomal protein L35a | -0.0321267 |
| FTL | ferritin, light polypeptide | -0.0320207 |
| MT1X | metallothionein 1X | -0.0320006 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0267096 |
| RPS24 | ribosomal protein S24 | -0.0241315 |
| RPL37A | ribosomal protein L37a | -0.0239613 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0239212 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0238597 |
| S100A4 | S100 calcium binding protein A4 | -0.0231624 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0223662 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221771 |
| RPS19 | ribosomal protein S19 | -0.0221065 |
| STC1 | stanniocalcin 1 | -0.0218647 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0214883 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0209391 |
| RPL28 | ribosomal protein L28 | -0.0208334 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207532 |
| PFN1 | profilin 1 | -0.0207177 |
| GNAS | GNAS complex locus | -0.02026 |
| RPS3 | ribosomal protein S3 | -0.0202183 |
| ACTG1 | actin gamma 1 | -0.0201524 |
| S100A11 | S100 calcium binding protein A11 | -0.0201468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0193495 |
| LMNA | lamin A/C | -0.0192707 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0192355 |
| RPL9 | ribosomal protein L9 | -0.0189832 |
| RPS6 | ribosomal protein S6 | -0.0189256 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0189031 |
| S100A6 | S100 calcium binding protein A6 | -0.0188627 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0188433 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0186474 |
| RPL36 | ribosomal protein L36 | -0.0183479 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179794 |
| SEC61G | Sec61 gamma subunit | -0.017962 |
| RPL12 | ribosomal protein L12 | -0.0177676 |
| HLA-C | major histocompatibility complex, class I, C | -0.0176174 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0176062 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0175764 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.017198 |
| RPS8 | ribosomal protein S8 | -0.0171813 |
| PRRC2C | proline-rich coiled-coil 2C | -0.017065 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0169934 |
| PRSS23 | protease, serine, 23 | -0.0169774 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0166545 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0165223 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0164855 |
| RPL23 | ribosomal protein L23 | -0.0164514 |
| FN1 | fibronectin 1 | -0.0163174 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0162838 |
| H3-3B | H3.3 histone B | -0.0161463 |
| RPL34 | ribosomal protein L34 | -0.0161121 |
| MYADM | myeloid-associated differentiation marker | -0.0157707 |
| RPL32 | ribosomal protein L32 | -0.015614 |
| CD81 | CD81 molecule | -0.0155562 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0154821 |
| KRT81 | keratin 81, type II | -0.0152634 |
| RPS21 | ribosomal protein S21 | -0.0152319 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0151878 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0147281 |
| RPL26 | ribosomal protein L26 | -0.0145586 |
| POMP | proteasome maturation protein | -0.0145366 |
| RPS14 | ribosomal protein S14 | -0.0143538 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0142522 |
| FAM162A | family with sequence similarity 162, member A | -0.0142414 |
| RPL31 | ribosomal protein L31 | -0.0140581 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0137782 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0137504 |
| SERF2 | small EDRK-rich factor 2 | -0.0136314 |
| RPS27A | ribosomal protein S27a | -0.01357 |
| POTEF | POTE ankyrin domain family, member F | -0.0135669 |
| RPL35 | ribosomal protein L35 | -0.0134378 |
| RPS13 | ribosomal protein S13 | -0.0134338 |
| CBX3 | chromobox homolog 3 | -0.0133736 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0133197 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0132815 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0132263 |
| RPL11 | ribosomal protein L11 | -0.013192 |
| RPS15 | ribosomal protein S15 | -0.0131288 |
| RBM25 | RNA binding motif protein 25 | -0.0128011 |
| RPS16 | ribosomal protein S16 | -0.0127808 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0124937 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0123486 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0122944 |
| RPS5 | ribosomal protein S5 | -0.0119398 |
