| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 8-Hydroxyquinoline_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.0385543 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0361248 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0354106 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0327803 |
| XPO1 | exportin 1 | 0.0296033 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.027947 |
| PUM2 | pumilio RNA-binding family member 2 | 0.026769 |
| ZNF292 | zinc finger protein 292 | 0.0254787 |
| CEP192 | centrosomal protein 192kDa | 0.0246111 |
| WDR43 | WD repeat domain 43 | 0.0237124 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0236942 |
| CCNL1 | cyclin L1 | 0.0221299 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.020963 |
| NEK7 | NIMA-related kinase 7 | 0.0209573 |
| TNPO1 | transportin 1 | 0.0209413 |
| TENM3 | teneurin transmembrane protein 3 | 0.0208744 |
| YBX1 | Y box binding protein 1 | 0.0201142 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0196189 |
| KLHL24 | kelch-like family member 24 | 0.0194658 |
| OXR1 | oxidation resistance 1 | 0.0189679 |
| ZNF638 | zinc finger protein 638 | 0.0187422 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0186549 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0180513 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.018037 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.017819 |
| PCNX1 | pecanex 1 | 0.0177895 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0177523 |
| CEP95 | centrosomal protein 95kDa | 0.0176776 |
| ETNK1 | ethanolamine kinase 1 | 0.0175481 |
| COG5 | component of oligomeric golgi complex 5 | 0.0175189 |
| SBF2 | SET binding factor 2 | 0.0174932 |
| YEATS2 | YEATS domain containing 2 | 0.0174558 |
| ATP11A | ATPase, class VI, type 11A | 0.0173823 |
| MATR3 | matrin 3 | 0.01734 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.017315 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0169811 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0169148 |
| MED13 | mediator complex subunit 13 | 0.0165537 |
| MED13L | mediator complex subunit 13-like | 0.0164477 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.016286 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0162777 |
| RTN4 | reticulon 4 | 0.0160526 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0160285 |
| SP3 | Sp3 transcription factor | 0.0159918 |
| PNN | pinin, desmosome associated protein | 0.0156199 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0155485 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0154966 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0151379 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0151366 |
| USP34 | ubiquitin specific peptidase 34 | 0.0146302 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0145926 |
| THOC1 | THO complex 1 | 0.0144937 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0143322 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0142542 |
| KIF5B | kinesin family member 5B | 0.0141309 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0140482 |
| TFG | TRK-fused gene | 0.0139574 |
| TSC22D2 | TSC22 domain family, member 2 | 0.013937 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0139314 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0138872 |
| NUP58 | nucleoporin 58 | 0.0138523 |
| RPL3 | ribosomal protein L3 | 0.013828 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0137863 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0137342 |
| TBK1 | TANK-binding kinase 1 | 0.0136753 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0136751 |
| CDK19 | cyclin-dependent kinase 19 | 0.01367 |
| HELB | helicase (DNA) B | 0.0135753 |
| OGA | O-GlcNAcase | 0.0135655 |
| RNF145 | ring finger protein 145 | 0.0135548 |
| KLC1 | kinesin light chain 1 | 0.0134682 |
| PCM1 | pericentriolar material 1 | 0.0133114 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0132983 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0132736 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0131749 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0130114 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0129235 |
| CPOX | coproporphyrinogen oxidase | 0.0128985 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0126877 |
| TNRC6A | trinucleotide repeat containing 6A | 0.012664 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0125724 |
| CEP70 | centrosomal protein 70kDa | 0.0125284 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0124485 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0124483 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0124316 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.012393 |
| TXNRD1 | thioredoxin reductase 1 | 0.0123919 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0123898 |
| TRIM37 | tripartite motif containing 37 | 0.0123294 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0123187 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0122228 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.012205 |
| TLK1 | tousled-like kinase 1 | 0.0121871 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0121414 |
| MEMO1 | mediator of cell motility 1 | 0.0121003 |
| PRKCI | protein kinase C, iota | 0.0120552 |
| USP24 | ubiquitin specific peptidase 24 | 0.012025 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0120187 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0119807 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0119392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.185501 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1755 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.151886 |
| HMGA2 | high mobility group AT-hook 2 | -0.11885 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.116208 |
| TMSB10 | thymosin beta 10 | -0.10932 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0956704 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.089894 |
| NLGN1 | neuroligin 1 | -0.0897892 |
| ACTG1 | actin gamma 1 | -0.0800473 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0735735 |
| PTMA | prothymosin, alpha | -0.0674204 |
| PCDH7 | protocadherin 7 | -0.0666979 |
| EHBP1 | EH domain binding protein 1 | -0.0620003 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0596886 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549052 |
| MMP12 | matrix metallopeptidase 12 | -0.0539402 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0537316 |
| AREG | amphiregulin | -0.0502447 |
| ZNF804A | zinc finger protein 804A | -0.0466521 |
| ANXA1 | annexin A1 | -0.0463178 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0463088 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0454863 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0429945 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0425372 |
| ASPH | aspartate beta-hydroxylase | -0.0425153 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0416673 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0393684 |
| EGR1 | early growth response 1 | -0.0383795 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0373678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0364291 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0363895 |
| INTS6 | integrator complex subunit 6 | -0.0360501 |
| NHSL1 | NHS-like 1 | -0.0354342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0346261 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0345002 |
| FTL | ferritin, light polypeptide | -0.0344218 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0343575 |
| RASAL2 | RAS protein activator like 2 | -0.0339558 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0329882 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0326092 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0321377 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0319626 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0319299 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0311793 |
| ADIPOR2 | adiponectin receptor 2 | -0.0307696 |
| CUX1 | cut-like homeobox 1 | -0.0303292 |
| S100A10 | S100 calcium binding protein A10 | -0.0297975 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0292448 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0288738 |
| LRRC23 | leucine rich repeat containing 23 | -0.0286802 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0283578 |
| MYPN | myopalladin | -0.0282111 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0277765 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0276508 |
| RPS3 | ribosomal protein S3 | -0.0272719 |
| TPI1 | triosephosphate isomerase 1 | -0.0272518 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0271688 |
| JMJD1C | jumonji domain containing 1C | -0.0268189 |
| RPL35A | ribosomal protein L35a | -0.0268067 |
| CLDN1 | claudin 1 | -0.026583 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0260889 |
| TPM4 | tropomyosin 4 | -0.025778 |
| MAP1B | microtubule-associated protein 1B | -0.0257045 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0249976 |
| PCDH9 | protocadherin 9 | -0.0249517 |
| GNAS | GNAS complex locus | -0.0248989 |
| RPS27A | ribosomal protein S27a | -0.0248256 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0246921 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0245652 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0243774 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0243184 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0240066 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0238799 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0236775 |
| RPS8 | ribosomal protein S8 | -0.0236359 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0233439 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0232274 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0231747 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0230258 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0228539 |
| PRDX1 | peroxiredoxin 1 | -0.0227607 |
| TUBA1B | tubulin, alpha 1b | -0.0222115 |
| RAB10 | RAB10, member RAS oncogene family | -0.0220972 |
| CMIP | c-Maf inducing protein | -0.0220682 |
| RPS24 | ribosomal protein S24 | -0.0218102 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.021654 |
| NABP1 | nucleic acid binding protein 1 | -0.0215952 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0215353 |
| AHNAK | AHNAK nucleoprotein | -0.0213015 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0212919 |
| CANX | calnexin | -0.0205016 |
| CALR | calreticulin | -0.0203766 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0202961 |
| RPL31 | ribosomal protein L31 | -0.0202693 |
| HDAC9 | histone deacetylase 9 | -0.0202679 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0202661 |
| RPL37 | ribosomal protein L37 | -0.0201687 |
| RPLP0 | ribosomal protein, large, P0 | -0.0200661 |
| BPTF | bromodomain PHD finger transcription factor | -0.0198377 |
