| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 8-Hydroxyquinoline_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.101194 |
| VCL | vinculin | 0.100468 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.100092 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.094547 |
| IGF2 | insulin-like growth factor 2 | 0.0945446 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0656716 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0568739 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0543445 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0530909 |
| RAD51B | RAD51 paralog B | 0.0524797 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0515326 |
| PRKCA | protein kinase C, alpha | 0.0484025 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0483324 |
| RIGI | RNA sensor RIG-I | 0.0477859 |
| MSI2 | musashi RNA-binding protein 2 | 0.0466749 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0461417 |
| DGKH | diacylglycerol kinase, eta | 0.0437012 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0436665 |
| DACH2 | dachshund family transcription factor 2 | 0.042843 |
| DTNA | dystrobrevin, alpha | 0.0426175 |
| PCDH15 | protocadherin-related 15 | 0.0404565 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0398191 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0387478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0385355 |
| AUTS2 | autism susceptibility candidate 2 | 0.0384051 |
| VMP1 | vacuole membrane protein 1 | 0.0382104 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.037889 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0378131 |
| NFIB | nuclear factor I/B | 0.0377947 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.037184 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0368994 |
| FAM13A | family with sequence similarity 13, member A | 0.0360528 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0357907 |
| ATXN1 | ataxin 1 | 0.034513 |
| RNF150 | ring finger protein 150 | 0.0335921 |
| RBM39 | RNA binding motif protein 39 | 0.0330229 |
| FHIT | fragile histidine triad | 0.0329906 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0323975 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.032134 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0316579 |
| INTS6 | integrator complex subunit 6 | 0.0313719 |
| USP3 | ubiquitin specific peptidase 3 | 0.0310922 |
| WDR45B | WD repeat domain 45B | 0.0304943 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.030457 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0293547 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289134 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0288363 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0283381 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0279195 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0277479 |
| DNM3 | dynamin 3 | 0.0276935 |
| TRIB2 | tribbles pseudokinase 2 | 0.0273786 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0270596 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0265713 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0261913 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0261286 |
| DPH6 | diphthamine biosynthesis 6 | 0.0259876 |
| PCDH17 | protocadherin 17 | 0.0258481 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.025645 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0255387 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0253979 |
| FERMT2 | fermitin family member 2 | 0.0253137 |
| STK38L | serine/threonine kinase 38 like | 0.0251999 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0251453 |
| SKIL | SKI-like proto-oncogene | 0.0250426 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0250006 |
| SMAD6 | SMAD family member 6 | 0.0249579 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0247142 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0246159 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0242072 |
| SP100 | SP100 nuclear antigen | 0.0241979 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0240883 |
| PLPP1 | phospholipid phosphatase 1 | 0.0240477 |
| MED13L | mediator complex subunit 13-like | 0.0236647 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0232477 |
| HOMER1 | homer scaffolding protein 1 | 0.0232181 |
| FAM168A | family with sequence similarity 168, member A | 0.0230678 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0229941 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0229687 |
| RALYL | RALY RNA binding protein-like | 0.0227882 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0225794 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0225758 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.02235 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0223121 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.022062 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0220134 |
| STXBP4 | syntaxin binding protein 4 | 0.021981 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0219234 |
| GLCCI1 | glucocorticoid induced 1 | 0.0219207 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0217523 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0215275 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0215162 |
| MCL1 | myeloid cell leukemia 1 | 0.0214841 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0210053 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.020799 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0207646 |
| TPM4 | tropomyosin 4 | 0.0206826 |
| TOP1 | topoisomerase (DNA) I | 0.0206622 |
| MYO6 | myosin VI | 0.0204818 |
| ZNF609 | zinc finger protein 609 | 0.0203484 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.124433 |
| PLAT | plasminogen activator, tissue | -0.0707368 |
| RPL19 | ribosomal protein L19 | -0.068182 |
| COL1A1 | collagen, type I, alpha 1 | -0.0580721 |
| ACTG1 | actin gamma 1 | -0.0580236 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.057348 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0549427 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0526649 |
| DSCAM | Down syndrome cell adhesion molecule | -0.051638 |
| RPL37A | ribosomal protein L37a | -0.0511938 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0511798 |
| FMN1 | formin 1 | -0.0505885 |
| RPL23 | ribosomal protein L23 | -0.0478445 |
| RPLP1 | ribosomal protein, large, P1 | -0.04691 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0465358 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0465274 |
| RPS3 | ribosomal protein S3 | -0.0464833 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0456391 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0451717 |
| TMSB10 | thymosin beta 10 | -0.0449349 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0424407 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0412203 |
| SET | SET nuclear proto-oncogene | -0.0408771 |
| B2M | beta-2-microglobulin | -0.0400766 |
| RPL7 | ribosomal protein L7 | -0.0399796 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0393862 |
| LMNA | lamin A/C | -0.0392745 |
| TPR | translocated promoter region, nuclear basket protein | -0.0390115 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0385796 |
| RPS6 | ribosomal protein S6 | -0.0383757 |
| RPS12 | ribosomal protein S12 | -0.0376218 |
| TBX2 | T-box 2 | -0.0373954 |
| RPL34 | ribosomal protein L34 | -0.0353198 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0351268 |
| DST | dystonin | -0.0347704 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0342317 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0340566 |
| CLTC | clathrin, heavy chain (Hc) | -0.0337908 |
| RPL38 | ribosomal protein L38 | -0.0336528 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0332214 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.033049 |
| RPL7A | ribosomal protein L7a | -0.0324154 |
| H3-3B | H3.3 histone B | -0.0322119 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0320915 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0318635 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0318092 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0317956 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0312713 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0312515 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0309586 |
| FNBP1 | formin binding protein 1 | -0.0307197 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0306498 |
| FTL | ferritin, light polypeptide | -0.0306327 |
| RPL8 | ribosomal protein L8 | -0.0295271 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0293849 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0292962 |
| RPL18 | ribosomal protein L18 | -0.0290936 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290727 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0290268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0289106 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0288364 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0288081 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0275034 |
| SEPTIN7 | septin 7 | -0.0271383 |
| RPL26 | ribosomal protein L26 | -0.0270302 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0270216 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0270118 |
| KIF5B | kinesin family member 5B | -0.0269579 |
| RPS8 | ribosomal protein S8 | -0.0268816 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0267898 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0260264 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0255147 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0253456 |
| SSH1 | slingshot protein phosphatase 1 | -0.0252956 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0252771 |
| CALR | calreticulin | -0.0252229 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0248513 |
| KLF6 | Kruppel-like factor 6 | -0.0246069 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.024533 |
| NKTR | natural killer cell triggering receptor | -0.0242918 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0241722 |
| SYT1 | synaptotagmin I | -0.0241708 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0240305 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.0239928 |
| RPS2 | ribosomal protein S2 | -0.023891 |
| NRG1 | neuregulin 1 | -0.0238701 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0236149 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0235844 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0235103 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0234374 |
| RPS17 | ribosomal protein S17 | -0.0233539 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0233196 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0231296 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0229159 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0226241 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0225897 |
| RPS27A | ribosomal protein S27a | -0.0224529 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0223855 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0222541 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0222135 |
