| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 8-Hydroxyquinoline_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.137866 |
| INTS6 | integrator complex subunit 6 | 0.116237 |
| LMO7 | LIM domain 7 | 0.0997872 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0829149 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0742551 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0617016 |
| SMAD3 | SMAD family member 3 | 0.0556567 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0540395 |
| ANXA2 | annexin A2 | 0.0531875 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0490854 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0461401 |
| RNF213 | ring finger protein 213 | 0.0441676 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.042634 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.039649 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0393527 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.037008 |
| PLSCR2 | phospholipid scramblase 2 | 0.0368158 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0361949 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0339566 |
| EFNB2 | ephrin-B2 | 0.0336666 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0326338 |
| VMP1 | vacuole membrane protein 1 | 0.0319714 |
| ASPH | aspartate beta-hydroxylase | 0.0317992 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0311697 |
| TOX3 | TOX high mobility group box family member 3 | 0.0307526 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0306869 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0306312 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0301388 |
| PRKCA | protein kinase C, alpha | 0.0298723 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0294389 |
| VCL | vinculin | 0.0293744 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0288127 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0287346 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0284353 |
| RIGI | RNA sensor RIG-I | 0.0280927 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0267112 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0265468 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0262634 |
| MYO1E | myosin IE | 0.0253084 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0250197 |
| EZR | ezrin | 0.0246755 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0236361 |
| RAD51B | RAD51 paralog B | 0.0234722 |
| FNIP2 | folliculin interacting protein 2 | 0.0232768 |
| TUFT1 | tuftelin 1 | 0.0229969 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0223181 |
| SP100 | SP100 nuclear antigen | 0.0221988 |
| POF1B | premature ovarian failure, 1B | 0.0216542 |
| PLSCR1 | phospholipid scramblase 1 | 0.0216519 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0214761 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0213789 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0211652 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0211455 |
| PHF3 | PHD finger protein 3 | 0.0208679 |
| SQSTM1 | sequestosome 1 | 0.0206696 |
| DST | dystonin | 0.0204759 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.020375 |
| NABP1 | nucleic acid binding protein 1 | 0.020259 |
| CTBP2 | C-terminal binding protein 2 | 0.020181 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0191691 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0184784 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0184434 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0183055 |
| KYNU | kynureninase | 0.018229 |
| DUSP10 | dual specificity phosphatase 10 | 0.0180271 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0178802 |
| ITGA6 | integrin, alpha 6 | 0.0174042 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0173731 |
| NCKAP5 | NCK-associated protein 5 | 0.0173112 |
| ATXN1 | ataxin 1 | 0.0171205 |
| GK | glycerol kinase | 0.0170871 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0170309 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0170223 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0169224 |
| KIAA1217 | KIAA1217 | 0.0168876 |
| MSI2 | musashi RNA-binding protein 2 | 0.0168356 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0168211 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0165204 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0164944 |
| UBAP2 | ubiquitin associated protein 2 | 0.0162085 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0161883 |
| MED13 | mediator complex subunit 13 | 0.0160241 |
| HOMER1 | homer scaffolding protein 1 | 0.0159554 |
| MX1 | MX dynamin-like GTPase 1 | 0.0159147 |
| LAMA4 | laminin, alpha 4 | 0.0158488 |
| EFNA5 | ephrin-A5 | 0.0158189 |
| PRKCE | protein kinase C, epsilon | 0.0157426 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0156292 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0155228 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0153469 |
| AREG | amphiregulin | 0.0153382 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0150327 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.014997 |
| MCU | mitochondrial calcium uniporter | 0.0146994 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0146181 |
| SERINC5 | serine incorporator 5 | 0.0146066 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0145893 |
| PRELID2 | PRELI domain containing 2 | 0.0144085 |
| USP53 | ubiquitin specific peptidase 53 | 0.0143481 |
| HKDC1 | hexokinase domain containing 1 | 0.0141403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.125184 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0858404 |
| LCN2 | lipocalin 2 | -0.0738614 |
| HLA-B | major histocompatibility complex, class I, B | -0.0677141 |
| PTMA | prothymosin, alpha | -0.0671982 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0594684 |
| RPL35A | ribosomal protein L35a | -0.0417052 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0413318 |
| TMSB10 | thymosin beta 10 | -0.0388034 |
| FTL | ferritin, light polypeptide | -0.0332048 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0331848 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0325447 |
| RPS6 | ribosomal protein S6 | -0.0315462 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0297813 |
| RPL23 | ribosomal protein L23 | -0.0284335 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0265614 |
| HLA-A | major histocompatibility complex, class I, A | -0.0263055 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0253657 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0253307 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0250377 |
| RPS19 | ribosomal protein S19 | -0.0222882 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0218026 |
| RPLP1 | ribosomal protein, large, P1 | -0.0215055 |
| RPL19 | ribosomal protein L19 | -0.021385 |
| RPL26 | ribosomal protein L26 | -0.0207718 |
| RPL37A | ribosomal protein L37a | -0.0206951 |
| RPS3 | ribosomal protein S3 | -0.0201696 |
| CALR | calreticulin | -0.0201469 |
| RPL34 | ribosomal protein L34 | -0.0199926 |
| RPS27 | ribosomal protein S27 | -0.0197408 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0196014 |
| MT2A | metallothionein 2A | -0.019492 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0194693 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0191505 |
| TXNIP | thioredoxin interacting protein | -0.0190986 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0190576 |
| RPS8 | ribosomal protein S8 | -0.0186558 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0186404 |
| EGR1 | early growth response 1 | -0.0185896 |
| TPM4 | tropomyosin 4 | -0.0182497 |
| NDRG1 | N-myc downstream regulated 1 | -0.0181713 |
| RPL12 | ribosomal protein L12 | -0.0181289 |
| HLA-C | major histocompatibility complex, class I, C | -0.0178067 |
| LYZ | lysozyme | -0.0177409 |
| RPS12 | ribosomal protein S12 | -0.0176394 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0174796 |
| S100A6 | S100 calcium binding protein A6 | -0.0170969 |
| RPL11 | ribosomal protein L11 | -0.0170401 |
| RPL31 | ribosomal protein L31 | -0.0169963 |
| RPL37 | ribosomal protein L37 | -0.0169306 |
| CANX | calnexin | -0.0163224 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.015564 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0154927 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0153633 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0151382 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0150842 |
| SERF2 | small EDRK-rich factor 2 | -0.0148403 |
| DSTN | destrin (actin depolymerizing factor) | -0.0148154 |
| CST3 | cystatin C | -0.0141958 |
| RPL9 | ribosomal protein L9 | -0.0140136 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0140106 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0139603 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0138438 |
| RPL35 | ribosomal protein L35 | -0.013741 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0136775 |
| S100A9 | S100 calcium binding protein A9 | -0.0136304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.013488 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0134677 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0133608 |
| HLA-E | major histocompatibility complex, class I, E | -0.0133342 |
| GOLGA4 | golgin A4 | -0.0133243 |
| RNF149 | ring finger protein 149 | -0.0132919 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.013052 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0130499 |
| EPCAM | epithelial cell adhesion molecule | -0.0130079 |
| SET | SET nuclear proto-oncogene | -0.0129249 |
| RPS24 | ribosomal protein S24 | -0.012814 |
| RPLP2 | ribosomal protein, large, P2 | -0.0127865 |
| RPL36A | ribosomal protein L36a | -0.012524 |
| RPS17 | ribosomal protein S17 | -0.0124615 |
| RPS13 | ribosomal protein S13 | -0.0124408 |
| RACK1 | receptor for activated C kinase 1 | -0.0124048 |
| TPI1 | triosephosphate isomerase 1 | -0.0122684 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0121967 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0121941 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.011798 |
| KRT19 | keratin 19, type I | -0.0117947 |
| RPS29 | ribosomal protein S29 | -0.0117685 |
| POTEF | POTE ankyrin domain family, member F | -0.011647 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0116144 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.011599 |
| WDR45B | WD repeat domain 45B | -0.0114496 |
| DIAPH3 | diaphanous-related formin 3 | -0.0113487 |
| H1-0 | H1.0 linker histone | -0.0113476 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0113105 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0112774 |
| BMP4 | bone morphogenetic protein 4 | -0.0112436 |
| RPL30 | ribosomal protein L30 | -0.0111716 |
| POMP | proteasome maturation protein | -0.0111292 |
| CSTB | cystatin B (stefin B) | -0.0111271 |