| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 8-Hydroxyquinoline_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.139967 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0727494 |
| NRXN3 | neurexin 3 | 0.0577941 |
| VCL | vinculin | 0.0546468 |
| CDH13 | cadherin 13 | 0.0510532 |
| COL5A1 | collagen, type V, alpha 1 | 0.0413526 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0358579 |
| GLIS3 | GLIS family zinc finger 3 | 0.035628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0355542 |
| NAV1 | neuron navigator 1 | 0.0349465 |
| PRSS23 | protease, serine, 23 | 0.0345393 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0335882 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.03261 |
| EGFR | epidermal growth factor receptor | 0.0325914 |
| RAD51B | RAD51 paralog B | 0.0316534 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0313915 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0313022 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290326 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0285622 |
| INTS6 | integrator complex subunit 6 | 0.028079 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0279934 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0273644 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.027047 |
| TNS3 | tensin 3 | 0.0251518 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0251351 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0250825 |
| HMGA2 | high mobility group AT-hook 2 | 0.0249725 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0240992 |
| KYNU | kynureninase | 0.0240918 |
| OXR1 | oxidation resistance 1 | 0.0240198 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0239642 |
| DST | dystonin | 0.0238449 |
| EFNA5 | ephrin-A5 | 0.0229261 |
| FN1 | fibronectin 1 | 0.0228158 |
| PRELID2 | PRELI domain containing 2 | 0.0223237 |
| FNIP1 | folliculin interacting protein 1 | 0.0222268 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0222197 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0219947 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0219314 |
| RAI14 | retinoic acid induced 14 | 0.0215338 |
| CANX | calnexin | 0.0212357 |
| GOLGB1 | golgin B1 | 0.0211836 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0208778 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0207354 |
| VEGFC | vascular endothelial growth factor C | 0.0203976 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0203819 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0202226 |
| UTRN | utrophin | 0.0201649 |
| ASPH | aspartate beta-hydroxylase | 0.020127 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0201208 |
| FHIT | fragile histidine triad | 0.0197008 |
| RUNX1 | runt-related transcription factor 1 | 0.0192978 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0189992 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0189434 |
| RRM2 | ribonucleotide reductase M2 | 0.0186633 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0183611 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0182433 |
| COL7A1 | collagen, type VII, alpha 1 | 0.018081 |
| RIN2 | Ras and Rab interactor 2 | 0.0176807 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0176631 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0176021 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0174631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0173329 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0170821 |
| HM13 | histocompatibility (minor) 13 | 0.0170815 |
| FER | fer (fps/fes related) tyrosine kinase | 0.01696 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0168951 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0167723 |
| WLS | wntless Wnt ligand secretion mediator | 0.0166685 |
| JPH2 | junctophilin 2 | 0.0166465 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0164918 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0157785 |
| SRBD1 | S1 RNA binding domain 1 | 0.0156353 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0156055 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0154452 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0154096 |
| SBF2 | SET binding factor 2 | 0.0154029 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0153477 |
| LAMB1 | laminin, beta 1 | 0.0153398 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0153161 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0152656 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0151689 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151288 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0150315 |
| MAGED1 | melanoma antigen family D1 | 0.0149624 |
| AOPEP | aminopeptidase O (putative) | 0.0149482 |
| FMNL2 | formin-like 2 | 0.0147296 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0145495 |
| GPATCH2L | G patch domain containing 2-like | 0.0145364 |
| RPS12 | ribosomal protein S12 | 0.0145096 |
| VEGFA | vascular endothelial growth factor A | 0.0143976 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0143743 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0143542 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0142897 |
| NBEAL1 | neurobeachin-like 1 | 0.0142417 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0142179 |
| FRMD4A | FERM domain containing 4A | 0.0141217 |
| YEATS2 | YEATS domain containing 2 | 0.0140919 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0140736 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0140443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199191 |
| TMSB10 | thymosin beta 10 | -0.172427 |
| MT2A | metallothionein 2A | -0.11744 |
| UBC | ubiquitin C | -0.0861595 |
| MT1X | metallothionein 1X | -0.0684481 |
| COL1A2 | collagen, type I, alpha 2 | -0.0669303 |
| SDC4 | syndecan 4 | -0.0602291 |
| B2M | beta-2-microglobulin | -0.0574589 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.05608 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0491459 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0486672 |
| COL1A1 | collagen, type I, alpha 1 | -0.0477362 |
| RTN4 | reticulon 4 | -0.0469824 |
| TXNIP | thioredoxin interacting protein | -0.0469452 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.046115 |
| ENO1 | enolase 1, (alpha) | -0.0453128 |
| GRB10 | growth factor receptor-bound protein 10 | -0.045189 |
| SPAG9 | sperm associated antigen 9 | -0.0449135 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0434374 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0410371 |
| PTMA | prothymosin, alpha | -0.0402902 |
| POTEF | POTE ankyrin domain family, member F | -0.0394715 |
| HLA-B | major histocompatibility complex, class I, B | -0.0378712 |
| H3-3B | H3.3 histone B | -0.0376354 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0366918 |
| VIM | vimentin | -0.0366125 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0361536 |
| COL5A2 | collagen, type V, alpha 2 | -0.0359062 |
| ANXA5 | annexin A5 | -0.0353878 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0349401 |
| IL6 | interleukin 6 | -0.0346698 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0341842 |
| WTAP | Wilms tumor 1 associated protein | -0.0340765 |
| JUN | jun proto-oncogene | -0.0321029 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0315221 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0312181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0293832 |
| RPL37A | ribosomal protein L37a | -0.0292035 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0285594 |
| FAM13A | family with sequence similarity 13, member A | -0.0283974 |
| FLNA | filamin A, alpha | -0.028079 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0279919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0279853 |
| ZNF292 | zinc finger protein 292 | -0.0279546 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.02779 |
| ZNF207 | zinc finger protein 207 | -0.0269858 |
| TOP1 | topoisomerase (DNA) I | -0.0269475 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0268271 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0266722 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0259707 |
| FTL | ferritin, light polypeptide | -0.0258518 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0258459 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0255996 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0246356 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0241199 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0241142 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0240411 |
| S100A10 | S100 calcium binding protein A10 | -0.0237616 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0237227 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0236361 |
| RPL32 | ribosomal protein L32 | -0.0233477 |
| MATR3 | matrin 3 | -0.0231921 |
| ARRDC3 | arrestin domain containing 3 | -0.0229947 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -0.0228817 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0225186 |
| RIGI | RNA sensor RIG-I | -0.0223762 |
| BSG | basigin (Ok blood group) | -0.022287 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0222448 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0221966 |
| GANAB | glucosidase, alpha; neutral AB | -0.0219048 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0214177 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0212685 |
| FLNB | filamin B, beta | -0.0212362 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0210226 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0209087 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0207614 |
| SEC61G | Sec61 gamma subunit | -0.0206133 |
| CCNI | cyclin I | -0.0204858 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0204567 |
| DEK | DEK proto-oncogene | -0.0203282 |
| ACVR1 | activin A receptor, type I | -0.0202801 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0201954 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0198829 |
| CUL4B | cullin 4B | -0.0198349 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0198296 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0197481 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0194341 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0193926 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0192303 |
| S100A9 | S100 calcium binding protein A9 | -0.0190026 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0188113 |
| THOC2 | THO complex 2 | -0.0188102 |
| RPS4X | ribosomal protein S4, X-linked | -0.0186807 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0186343 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.018626 |
| RLIM | ring finger protein, LIM domain interacting | -0.0185935 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.018547 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0185408 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0184414 |
| RPS27A | ribosomal protein S27a | -0.0184395 |
