| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 8-Hydroxyquinoline perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 8-Hydroxyquinoline_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.170811 |
| FNDC3B | fibronectin type III domain containing 3B | 0.083641 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0714737 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0667515 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.064484 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.062079 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0533734 |
| IGF2 | insulin-like growth factor 2 | 0.0519997 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0514481 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0511648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0494521 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0487954 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0465483 |
| PYGL | phosphorylase, glycogen, liver | 0.0460836 |
| ATXN1 | ataxin 1 | 0.0420103 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0417015 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0413674 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0405011 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0399992 |
| ZNF609 | zinc finger protein 609 | 0.0376418 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0369879 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0367159 |
| TAOK1 | TAO kinase 1 | 0.0361045 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0359555 |
| ANGPTL4 | angiopoietin-like 4 | 0.0354273 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0352811 |
| PRKCA | protein kinase C, alpha | 0.0350606 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0348817 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0348779 |
| NGLY1 | N-glycanase 1 | 0.0345528 |
| PHF21A | PHD finger protein 21A | 0.0336314 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.032621 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0325131 |
| FLNB | filamin B, beta | 0.0321754 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0321422 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315894 |
| PHF3 | PHD finger protein 3 | 0.0311615 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.030883 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0307655 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0305722 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.03046 |
| ANXA1 | annexin A1 | 0.0300625 |
| MYOF | myoferlin | 0.0298407 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0293254 |
| INSIG2 | insulin induced gene 2 | 0.0289986 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0289707 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0289337 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0285066 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0280222 |
| NDRG1 | N-myc downstream regulated 1 | 0.0273867 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0270113 |
| MYO9A | myosin IXA | 0.0269305 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0269031 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0266461 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0266197 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0264032 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0262355 |
| CFH | complement factor H | 0.0260526 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0260292 |
| NBEAL1 | neurobeachin-like 1 | 0.0259758 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0259719 |
| PARD3 | par-3 family cell polarity regulator | 0.0259065 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0258603 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0257935 |
| SQSTM1 | sequestosome 1 | 0.0256609 |
| CPNE8 | copine VIII | 0.0253738 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0252444 |
| FTO | fat mass and obesity associated | 0.025152 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0251465 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0249263 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0249259 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0247185 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0245204 |
| SRPK1 | SRSF protein kinase 1 | 0.0245012 |
| LRRC49 | leucine rich repeat containing 49 | 0.0244464 |
| DTNA | dystrobrevin, alpha | 0.0242846 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0242544 |
| ATXN2 | ataxin 2 | 0.0240831 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0240576 |
| FAM13A | family with sequence similarity 13, member A | 0.0239823 |
| CDC42SE2 | CDC42 small effector 2 | 0.0238147 |
| USP53 | ubiquitin specific peptidase 53 | 0.0237642 |
| EXOC5 | exocyst complex component 5 | 0.0237128 |
| INSIG1 | insulin induced gene 1 | 0.023624 |
| MYADM | myeloid-associated differentiation marker | 0.0234313 |
| FN1 | fibronectin 1 | 0.0234267 |
| COG6 | component of oligomeric golgi complex 6 | 0.0233178 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0233103 |
| ENO1 | enolase 1, (alpha) | 0.0232984 |
| PCDH7 | protocadherin 7 | 0.0232731 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0231692 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230732 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0230242 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 0.022701 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0225279 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.0224947 |
| CDK13 | cyclin-dependent kinase 13 | 0.0224515 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0224292 |
| ATM | ATM serine/threonine kinase | 0.0223872 |
| RAI1 | retinoic acid induced 1 | 0.0222471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217874 |
| OSMR | oncostatin M receptor | -0.0863774 |
| SMYD3 | SET and MYND domain containing 3 | -0.0705725 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0649419 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.061297 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0593001 |
| GOLGA4 | golgin A4 | -0.0555798 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0535232 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0533178 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0524397 |
| MKI67 | marker of proliferation Ki-67 | -0.0497669 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0490342 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0480387 |
| ACTG1 | actin gamma 1 | -0.0477967 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0477105 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0475294 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0470809 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0467523 |
| DIAPH3 | diaphanous-related formin 3 | -0.0457164 |
| EXOC6B | exocyst complex component 6B | -0.0445458 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0444766 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0432982 |
| VIM | vimentin | -0.0420306 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0406276 |
| AHNAK | AHNAK nucleoprotein | -0.0403357 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0403135 |
| CD44 | CD44 molecule (Indian blood group) | -0.0397554 |
| RPS6 | ribosomal protein S6 | -0.0394359 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0391251 |
| RBM39 | RNA binding motif protein 39 | -0.0367332 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0364388 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360063 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0356143 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0354338 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0348231 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0345419 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0344366 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0341081 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0337356 |
| RPS17 | ribosomal protein S17 | -0.033614 |
| IL6ST | interleukin 6 signal transducer | -0.0332936 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0323924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0320612 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0320497 |
| RPL23 | ribosomal protein L23 | -0.0318471 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0318309 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0315679 |
| SMAD3 | SMAD family member 3 | -0.0312778 |
| RPL36 | ribosomal protein L36 | -0.0312373 |
| RACK1 | receptor for activated C kinase 1 | -0.0311856 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0309615 |
| PHF14 | PHD finger protein 14 | -0.0306684 |
| RPL35 | ribosomal protein L35 | -0.030434 |
| RPLP2 | ribosomal protein, large, P2 | -0.0303641 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0302118 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0297072 |
| MSN | moesin | -0.0296056 |
| YBX3 | Y box binding protein 3 | -0.0294493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0294338 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0294036 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0291118 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | -0.0289998 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287467 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0287307 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286324 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0285921 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0283741 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0278905 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0274311 |
| KIF4A | kinesin family member 4A | -0.0273942 |
| RPS12 | ribosomal protein S12 | -0.0269071 |
| CEP295 | centrosomal protein 295kDa | -0.0268642 |
| RPS13 | ribosomal protein S13 | -0.0268492 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.0268028 |
| UBB | ubiquitin B | -0.0267836 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.026753 |
| RPS28 | ribosomal protein S28 | -0.0264227 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0264013 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0261686 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0261628 |
| CENPF | centromere protein F, 350/400kDa | -0.0260482 |
| VMP1 | vacuole membrane protein 1 | -0.0259167 |
| VCL | vinculin | -0.0258502 |
| RPL32 | ribosomal protein L32 | -0.0256473 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0256445 |
| H3-3B | H3.3 histone B | -0.0256256 |
| RPL11 | ribosomal protein L11 | -0.0254185 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0253502 |
| CAB39 | calcium binding protein 39 | -0.0251543 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0250472 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0250053 |
| RSU1 | Ras suppressor protein 1 | -0.0249717 |
| KIF20B | kinesin family member 20B | -0.0248064 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0245437 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0245136 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0243995 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0243814 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0242359 |
| MDM4 | MDM4, p53 regulator | -0.0240453 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0238027 |
