| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.209233 |
| PODXL | podocalyxin-like | 0.144215 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.104097 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0922983 |
| PLAT | plasminogen activator, tissue | 0.0856723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0808448 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0788954 |
| HDAC9 | histone deacetylase 9 | 0.0740566 |
| CD44 | CD44 molecule (Indian blood group) | 0.0726855 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0600022 |
| MT2A | metallothionein 2A | 0.057792 |
| VIM | vimentin | 0.0517135 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0512072 |
| SUCNR1 | succinate receptor 1 | 0.0510528 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0508893 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0466779 |
| STC1 | stanniocalcin 1 | 0.0447059 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0439703 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.042087 |
| B2M | beta-2-microglobulin | 0.0400185 |
| RPS2 | ribosomal protein S2 | 0.0387181 |
| CTSB | cathepsin B | 0.0387133 |
| CSTB | cystatin B (stefin B) | 0.0383385 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0365722 |
| RPL37A | ribosomal protein L37a | 0.0347784 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0347243 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0344167 |
| SQSTM1 | sequestosome 1 | 0.033695 |
| RPS12 | ribosomal protein S12 | 0.0322217 |
| NAV1 | neuron navigator 1 | 0.0320822 |
| BPTF | bromodomain PHD finger transcription factor | 0.0309696 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0305113 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0300392 |
| RPS6 | ribosomal protein S6 | 0.0280453 |
| SET | SET nuclear proto-oncogene | 0.0279086 |
| SEPTIN9 | septin 9 | 0.0276578 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0272069 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0270031 |
| COL3A1 | collagen, type III, alpha 1 | 0.0269333 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0267751 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.026003 |
| E2F7 | E2F transcription factor 7 | 0.0259879 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0259089 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0254804 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0254538 |
| RND3 | Rho family GTPase 3 | 0.0254316 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0250688 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0249979 |
| RPS8 | ribosomal protein S8 | 0.0247729 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0246355 |
| DSPP | dentin sialophosphoprotein | 0.0235119 |
| TPM3 | tropomyosin 3 | 0.0233705 |
| SLFN5 | schlafen family member 5 | 0.0233186 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0231075 |
| SMYD3 | SET and MYND domain containing 3 | 0.0229381 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0228871 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022833 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0226395 |
| ENO1 | enolase 1, (alpha) | 0.0219442 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0218022 |
| JMJD1C | jumonji domain containing 1C | 0.0217312 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0215103 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0211399 |
| TPM4 | tropomyosin 4 | 0.021058 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0210225 |
| MKI67 | marker of proliferation Ki-67 | 0.0209308 |
| SP100 | SP100 nuclear antigen | 0.0206501 |
| PMP22 | peripheral myelin protein 22 | 0.0202591 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0200461 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0199713 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198611 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0198372 |
| TXNIP | thioredoxin interacting protein | 0.0196408 |
| SMAD3 | SMAD family member 3 | 0.019612 |
| ANKRD36 | ankyrin repeat domain 36 | 0.019497 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0192479 |
| EHBP1 | EH domain binding protein 1 | 0.0191477 |
| DNMBP | dynamin binding protein | 0.0191366 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0191216 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0190705 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0189568 |
| VEGFC | vascular endothelial growth factor C | 0.018729 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0187131 |
| ASPH | aspartate beta-hydroxylase | 0.0186419 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0183252 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0183014 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0181618 |
| BCL2L1 | BCL2-like 1 | 0.0181229 |
| CENPF | centromere protein F, 350/400kDa | 0.0179973 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0179376 |
| ITGA6 | integrin, alpha 6 | 0.0176742 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.0176579 |
| MSN | moesin | 0.0174546 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0174099 |
| REST | RE1-silencing transcription factor | 0.017389 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0173122 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.01702 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0169996 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0166177 |
| RPS17 | ribosomal protein S17 | 0.016571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.23517 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.228856 |
| TMSB10 | thymosin beta 10 | -0.218344 |
| LOX | lysyl oxidase | -0.118437 |
| COL5A1 | collagen, type V, alpha 1 | -0.114462 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.112161 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.111829 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10524 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0798181 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0752227 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0727854 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0705143 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0704162 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0696358 |
| LOXL2 | lysyl oxidase-like 2 | -0.0676967 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0675629 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0657187 |
| LMNA | lamin A/C | -0.0620179 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0610303 |
| FBN1 | fibrillin 1 | -0.0607135 |
| THBS2 | thrombospondin 2 | -0.0601167 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0597222 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0595938 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0588084 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0570616 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0530862 |
| TAGLN2 | transgelin 2 | -0.051576 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0484386 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0483124 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0470803 |
| UBC | ubiquitin C | -0.0458528 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0451818 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0450944 |
| NDRG1 | N-myc downstream regulated 1 | -0.0448755 |
| CDH13 | cadherin 13 | -0.0436296 |
| HDLBP | high density lipoprotein binding protein | -0.0418819 |
| JAZF1 | JAZF zinc finger 1 | -0.0400327 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0399298 |
| AHNAK | AHNAK nucleoprotein | -0.0398846 |
| RIGI | RNA sensor RIG-I | -0.0382838 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0378552 |
| COPA | coatomer protein complex, subunit alpha | -0.0377591 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0376932 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0371285 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0369799 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0366217 |
| SPAG9 | sperm associated antigen 9 | -0.0364862 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0362834 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0362447 |
| FN1 | fibronectin 1 | -0.0353348 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0349406 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0348506 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0344069 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342518 |
| ADM | adrenomedullin | -0.0342072 |
| EGFR | epidermal growth factor receptor | -0.0339328 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0338126 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0334845 |
| RRBP1 | ribosome binding protein 1 | -0.0323141 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.032294 |
| DENND1A | DENN/MADD domain containing 1A | -0.0321653 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0321415 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0320462 |
| JUN | jun proto-oncogene | -0.0315493 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0315103 |
| AUTS2 | autism susceptibility candidate 2 | -0.0314791 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0313835 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0312297 |
| MEIS2 | Meis homeobox 2 | -0.0307081 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0306935 |
| MSI2 | musashi RNA-binding protein 2 | -0.0292084 |
| C1D | C1D nuclear receptor corepressor | -0.0290296 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0288765 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0287168 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0286626 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.028155 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.027233 |
| BSG | basigin (Ok blood group) | -0.0270073 |
| ANXA2 | annexin A2 | -0.026742 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.0266251 |
| INSIG1 | insulin induced gene 1 | -0.0262973 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0262463 |
| SEC24A | SEC24 family member A | -0.0258226 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0255102 |
| CAVIN1 | caveolae associated protein 1 | -0.0254938 |
| MT1X | metallothionein 1X | -0.0252743 |
| COL5A2 | collagen, type V, alpha 2 | -0.0252155 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.025058 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.02486 |
| CTBP2 | C-terminal binding protein 2 | -0.0246285 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0245645 |
| PTMA | prothymosin, alpha | -0.0245624 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0238919 |
| IL7R | interleukin 7 receptor | -0.0238765 |
| TGFB1 | transforming growth factor, beta 1 | -0.0235625 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0230267 |
| CANX | calnexin | -0.0229814 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0228996 |
| S100A4 | S100 calcium binding protein A4 | -0.0227775 |
| MAP1B | microtubule-associated protein 1B | -0.0227478 |
