| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.212763 |
| KYNU | kynureninase | 0.0800937 |
| NAV2 | neuron navigator 2 | 0.0725181 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0722485 |
| RND3 | Rho family GTPase 3 | 0.0618361 |
| B2M | beta-2-microglobulin | 0.0607249 |
| EXT1 | exostosin glycosyltransferase 1 | 0.056897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0539493 |
| RPL37A | ribosomal protein L37a | 0.0518613 |
| RPS8 | ribosomal protein S8 | 0.0507981 |
| RPS2 | ribosomal protein S2 | 0.0499997 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0487802 |
| MT2A | metallothionein 2A | 0.0485176 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0478384 |
| SP100 | SP100 nuclear antigen | 0.0474299 |
| PDLIM5 | PDZ and LIM domain 5 | 0.046669 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0461889 |
| HDAC9 | histone deacetylase 9 | 0.0459473 |
| INTS6 | integrator complex subunit 6 | 0.045833 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0457336 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0454183 |
| RPS6 | ribosomal protein S6 | 0.0445003 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0435633 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0433038 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0431227 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0426808 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0424082 |
| BPTF | bromodomain PHD finger transcription factor | 0.0416277 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0408518 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0397765 |
| CUX1 | cut-like homeobox 1 | 0.0391255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0385455 |
| GPC5 | glypican 5 | 0.0384867 |
| RPS12 | ribosomal protein S12 | 0.0374166 |
| RPL12 | ribosomal protein L12 | 0.0366497 |
| SEPTIN9 | septin 9 | 0.0364241 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0363152 |
| PLIN2 | perilipin 2 | 0.036216 |
| EHBP1 | EH domain binding protein 1 | 0.036139 |
| VIM | vimentin | 0.0360789 |
| EXOC4 | exocyst complex component 4 | 0.0359971 |
| GOLGB1 | golgin B1 | 0.0359143 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0358479 |
| RPS17 | ribosomal protein S17 | 0.0353894 |
| LYST | lysosomal trafficking regulator | 0.0353477 |
| SFTPA2 | surfactant protein A2 | 0.0343781 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0343043 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0323211 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0322645 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0316721 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305723 |
| RPL31 | ribosomal protein L31 | 0.0304467 |
| IFI44L | interferon-induced protein 44-like | 0.0302206 |
| HLA-B | major histocompatibility complex, class I, B | 0.0301143 |
| UBAP2 | ubiquitin associated protein 2 | 0.0293998 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0293091 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0292864 |
| TUT7 | terminal uridylyl transferase 7 | 0.0288815 |
| RPS3 | ribosomal protein S3 | 0.0280304 |
| EGFR | epidermal growth factor receptor | 0.0276736 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0276139 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0268372 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0267899 |
| RPL7 | ribosomal protein L7 | 0.0262027 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0261176 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0254152 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0253238 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0252238 |
| SET | SET nuclear proto-oncogene | 0.0251499 |
| RIGI | RNA sensor RIG-I | 0.0247771 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0246989 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0244203 |
| PRKCA | protein kinase C, alpha | 0.0242661 |
| RPL37 | ribosomal protein L37 | 0.0238877 |
| MYO9A | myosin IXA | 0.023845 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0236822 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0236588 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0235688 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0231912 |
| RNF213 | ring finger protein 213 | 0.0231457 |
| HM13 | histocompatibility (minor) 13 | 0.0230457 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0227215 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0224562 |
| AGO3 | argonaute RISC catalytic component 3 | 0.022269 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0221368 |
| RAD51B | RAD51 paralog B | 0.0221089 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0218426 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0218133 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0217169 |
| SLC39A11 | solute carrier family 39, member 11 | 0.021682 |
| TUSC3 | tumor suppressor candidate 3 | 0.0216091 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | 0.0216018 |
| MX1 | MX dynamin-like GTPase 1 | 0.0215773 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0213547 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0212728 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0211979 |
| BNC2 | basonuclin 2 | 0.0211761 |
| RPL26 | ribosomal protein L26 | 0.0211672 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0208984 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0208889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.211346 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153034 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.105164 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0904413 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0895751 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.088492 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0800511 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0689394 |
| ASPH | aspartate beta-hydroxylase | -0.0645981 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0613336 |
| MAP1B | microtubule-associated protein 1B | -0.0610002 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0593333 |
| RHEB | Ras homolog enriched in brain | -0.0554562 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0552297 |
| PTMA | prothymosin, alpha | -0.0544774 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0543725 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0543452 |
| DENND2B | DENN domain containing 2B | -0.053916 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0536102 |
| PFN1 | profilin 1 | -0.0535599 |
| TMSB10 | thymosin beta 10 | -0.0514039 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0499305 |
| RRBP1 | ribosome binding protein 1 | -0.049742 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0495087 |
| USP3 | ubiquitin specific peptidase 3 | -0.0488545 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0485654 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0476467 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0474322 |
| NRP2 | neuropilin 2 | -0.0469774 |
| CADM1 | cell adhesion molecule 1 | -0.046662 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.046649 |
| HMGB1 | high mobility group box 1 | -0.0458527 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0449011 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.044382 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0440734 |
| GDF15 | growth differentiation factor 15 | -0.0436546 |
| RBM39 | RNA binding motif protein 39 | -0.0422938 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0416615 |
| HSPB1 | heat shock 27kDa protein 1 | -0.041554 |
| CD70 | CD70 molecule | -0.0415228 |
| G0S2 | G0/G1 switch 2 | -0.0413505 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0413075 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0410243 |
| RAB1A | RAB1A, member RAS oncogene family | -0.040598 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0405864 |
| FAT1 | FAT atypical cadherin 1 | -0.0404197 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0403012 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.040256 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0399503 |
| TXNRD1 | thioredoxin reductase 1 | -0.0395406 |
| PKM | pyruvate kinase, muscle | -0.0395138 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0383412 |
| ANXA5 | annexin A5 | -0.0381893 |
| QKI | QKI, KH domain containing, RNA binding | -0.0380598 |
| ATP13A3 | ATPase type 13A3 | -0.0378055 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0363094 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0359545 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0351571 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0350496 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0346613 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346181 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0343604 |
| RTN4 | reticulon 4 | -0.0343204 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0342006 |
| ANLN | anillin, actin binding protein | -0.034192 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0336523 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0335327 |
| AZIN1 | antizyme inhibitor 1 | -0.033424 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0334088 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0328399 |
| TFG | TRK-fused gene | -0.0324011 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0323569 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0320962 |
| SDCBP | syndecan binding protein (syntenin) | -0.0314714 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0314627 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0314022 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0313129 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0312704 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0311716 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0311424 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0310196 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0309815 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0309466 |
| CLINT1 | clathrin interactor 1 | -0.0307392 |
| APP | amyloid beta (A4) precursor protein | -0.0305557 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0305441 |
| NOP58 | NOP58 ribonucleoprotein | -0.0304712 |
| ECT2 | epithelial cell transforming 2 | -0.0304459 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0302782 |
| INSIG1 | insulin induced gene 1 | -0.0301828 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0301763 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0301685 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0299314 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0298088 |
| MATR3 | matrin 3 | -0.0297363 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.029699 |
| OLA1 | Obg-like ATPase 1 | -0.0296087 |
| MORF4L1 | mortality factor 4 like 1 | -0.0295917 |
| GOLGA4 | golgin A4 | -0.0294641 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0293196 |
