| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.204561 |
| KYNU | kynureninase | 0.141945 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.117223 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.111665 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.106081 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.104582 |
| ACTG1 | actin gamma 1 | 0.093085 |
| VIM | vimentin | 0.0702562 |
| STC1 | stanniocalcin 1 | 0.0688071 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0630514 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0587987 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.056168 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0559505 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0554199 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.055351 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0535245 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0532431 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0528217 |
| RPS6 | ribosomal protein S6 | 0.0510745 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508605 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0506453 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0478932 |
| RND3 | Rho family GTPase 3 | 0.0475209 |
| RPS2 | ribosomal protein S2 | 0.0437583 |
| RPLP1 | ribosomal protein, large, P1 | 0.0423444 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0420532 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.041962 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0418823 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0417621 |
| USP47 | ubiquitin specific peptidase 47 | 0.0414446 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0414163 |
| POTEF | POTE ankyrin domain family, member F | 0.0407879 |
| MYO10 | myosin X | 0.0384351 |
| BPTF | bromodomain PHD finger transcription factor | 0.0383398 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0382192 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0371383 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0352719 |
| LMO7 | LIM domain 7 | 0.0352298 |
| INTS6 | integrator complex subunit 6 | 0.0342306 |
| MAP7 | microtubule-associated protein 7 | 0.0337442 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0334112 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0333278 |
| DUSP16 | dual specificity phosphatase 16 | 0.0330812 |
| SQSTM1 | sequestosome 1 | 0.0330768 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0328825 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0326551 |
| RHCG | Rh family, C glycoprotein | 0.0320139 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0317792 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.031656 |
| ANXA1 | annexin A1 | 0.0308909 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.030711 |
| AADAC | arylacetamide deacetylase | 0.0301924 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0300624 |
| NTN4 | netrin 4 | 0.0299161 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0298748 |
| PALLD | palladin, cytoskeletal associated protein | 0.0278247 |
| AXL | AXL receptor tyrosine kinase | 0.0277154 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0277121 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0274404 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0271565 |
| RAB10 | RAB10, member RAS oncogene family | 0.0271047 |
| RSPO3 | R-spondin 3 | 0.0269821 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0267574 |
| SMYD3 | SET and MYND domain containing 3 | 0.0266978 |
| ERBIN | erbb2 interacting protein | 0.0266117 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0265699 |
| BMP6 | bone morphogenetic protein 6 | 0.0264864 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0262957 |
| DUSP5 | dual specificity phosphatase 5 | 0.0262104 |
| ETNK1 | ethanolamine kinase 1 | 0.0261344 |
| WWOX | WW domain containing oxidoreductase | 0.0259731 |
| FAT1 | FAT atypical cadherin 1 | 0.0259444 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0259141 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0258511 |
| HMGA2 | high mobility group AT-hook 2 | 0.0254851 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0247849 |
| MCL1 | myeloid cell leukemia 1 | 0.0247274 |
| RPL4 | ribosomal protein L4 | 0.024394 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0243647 |
| RPS16 | ribosomal protein S16 | 0.0236881 |
| RPS12 | ribosomal protein S12 | 0.0234149 |
| UBAP2 | ubiquitin associated protein 2 | 0.0232321 |
| CREBBP | CREB binding protein | 0.0232051 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0227919 |
| CCDC88A | coiled-coil domain containing 88A | 0.0227152 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0223907 |
| RPLP0 | ribosomal protein, large, P0 | 0.0223735 |
| GRAMD1B | GRAM domain containing 1B | 0.0223522 |
| MED13 | mediator complex subunit 13 | 0.0221004 |
| RPL7 | ribosomal protein L7 | 0.0218003 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0215952 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0214941 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0213101 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0210809 |
| VCL | vinculin | 0.0210786 |
| ANXA2 | annexin A2 | 0.0209717 |
| PDZD8 | PDZ domain containing 8 | 0.0209551 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0209413 |
| RPL23 | ribosomal protein L23 | 0.0208671 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0208514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.108341 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.106133 |
| TMSB10 | thymosin beta 10 | -0.0934074 |
| EFNA5 | ephrin-A5 | -0.0902476 |
| NDRG1 | N-myc downstream regulated 1 | -0.0897115 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0867716 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.077004 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0754374 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0752505 |
| PGK1 | phosphoglycerate kinase 1 | -0.0681819 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0666065 |
| USP3 | ubiquitin specific peptidase 3 | -0.0540816 |
| SBF2 | SET binding factor 2 | -0.0540717 |
| RRBP1 | ribosome binding protein 1 | -0.0526884 |
| MT2A | metallothionein 2A | -0.0526433 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0524573 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0517037 |
| MAP1B | microtubule-associated protein 1B | -0.0513941 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0501903 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0496689 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0490236 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0486968 |
| CANX | calnexin | -0.0486686 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0485337 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0482514 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0476725 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.046708 |
| GOLGA4 | golgin A4 | -0.0466115 |
| MT1X | metallothionein 1X | -0.0466013 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0460455 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0456294 |
| TNS3 | tensin 3 | -0.0441548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0436709 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0420421 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0418392 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0416801 |
| CLINT1 | clathrin interactor 1 | -0.0415318 |
| EHBP1 | EH domain binding protein 1 | -0.0406963 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0406056 |
| FLNB | filamin B, beta | -0.0395568 |
| CLTC | clathrin, heavy chain (Hc) | -0.0393866 |
| HELZ | helicase with zinc finger | -0.0392477 |
| RIN2 | Ras and Rab interactor 2 | -0.0391463 |
| HDLBP | high density lipoprotein binding protein | -0.0387227 |
| ATG7 | autophagy related 7 | -0.0383399 |
| COPA | coatomer protein complex, subunit alpha | -0.0381358 |
| LAMB3 | laminin, beta 3 | -0.037843 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0375186 |
| CMIP | c-Maf inducing protein | -0.0371014 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0368606 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.036516 |
| RNF213 | ring finger protein 213 | -0.0362384 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0360609 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0348482 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0347958 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.034668 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0346052 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0342445 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0340705 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0340512 |
| CALU | calumenin | -0.0335694 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0335425 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0334089 |
| THOC2 | THO complex 2 | -0.0333068 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0331617 |
| GPC6 | glypican 6 | -0.0330136 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0327637 |
| LDHA | lactate dehydrogenase A | -0.0324333 |
| SRP54 | signal recognition particle 54kDa | -0.0323841 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0322416 |
| FTL | ferritin, light polypeptide | -0.0317682 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0316907 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0315683 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0315375 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0309362 |
| PTMA | prothymosin, alpha | -0.0307665 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0305951 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0304679 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0304575 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0299346 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0297659 |
| SPAG9 | sperm associated antigen 9 | -0.0296858 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0294981 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0294427 |
| WDR45B | WD repeat domain 45B | -0.0294126 |
| FNBP4 | formin binding protein 4 | -0.0294009 |
| AOPEP | aminopeptidase O (putative) | -0.0293271 |
| ZNF292 | zinc finger protein 292 | -0.0292887 |
| LOXL2 | lysyl oxidase-like 2 | -0.0285635 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0285628 |
| NBAS | neuroblastoma amplified sequence | -0.0285399 |
| RBM39 | RNA binding motif protein 39 | -0.0282626 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0282366 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0281187 |
| FAM13A | family with sequence similarity 13, member A | -0.0279617 |
| DAPK1 | death-associated protein kinase 1 | -0.0279113 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0274548 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0273614 |
| WASF2 | WAS protein family, member 2 | -0.0270236 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0269772 |
