| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0967716 |
| MKI67 | marker of proliferation Ki-67 | 0.0803083 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0534396 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.048768 |
| PCDH7 | protocadherin 7 | 0.0483216 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0443034 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0418289 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0416728 |
| RPS12 | ribosomal protein S12 | 0.0416693 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.041561 |
| MYO9A | myosin IXA | 0.0410457 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0405138 |
| OGA | O-GlcNAcase | 0.0399751 |
| RPS2 | ribosomal protein S2 | 0.0392092 |
| PDE10A | phosphodiesterase 10A | 0.0387907 |
| SQSTM1 | sequestosome 1 | 0.0376652 |
| HMGA2 | high mobility group AT-hook 2 | 0.0375719 |
| RPS6 | ribosomal protein S6 | 0.0370761 |
| IGF2 | insulin-like growth factor 2 | 0.0370631 |
| PRELID2 | PRELI domain containing 2 | 0.0369149 |
| SET | SET nuclear proto-oncogene | 0.036747 |
| NAV2 | neuron navigator 2 | 0.0352366 |
| RPS8 | ribosomal protein S8 | 0.0348094 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0313093 |
| MT2A | metallothionein 2A | 0.0306856 |
| FN1 | fibronectin 1 | 0.0303403 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0294982 |
| TNS3 | tensin 3 | 0.0293192 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0286048 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0285394 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0282828 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0282151 |
| RPL37A | ribosomal protein L37a | 0.0281807 |
| AHNAK | AHNAK nucleoprotein | 0.0280415 |
| RPL5 | ribosomal protein L5 | 0.0271062 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0264742 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0263009 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.026195 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0259908 |
| ARRDC3 | arrestin domain containing 3 | 0.0258661 |
| RPL26 | ribosomal protein L26 | 0.0254583 |
| RPS20 | ribosomal protein S20 | 0.0249854 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0243112 |
| IER3 | immediate early response 3 | 0.0241662 |
| RPL7 | ribosomal protein L7 | 0.023992 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0233058 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.022849 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0225955 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0223772 |
| RAD51B | RAD51 paralog B | 0.0217683 |
| MED13 | mediator complex subunit 13 | 0.0217063 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0214183 |
| VIM | vimentin | 0.0209551 |
| ADM | adrenomedullin | 0.0205445 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0203179 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0200103 |
| CENPE | centromere protein E, 312kDa | 0.0199074 |
| LMO7 | LIM domain 7 | 0.0198634 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0198168 |
| CNTRL | centriolin | 0.0196021 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0194194 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0193998 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0192912 |
| HOXA3 | homeobox A3 | 0.0191885 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0189628 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.018962 |
| TPX2 | TPX2, microtubule-associated | 0.0188795 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.018856 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0187981 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0186405 |
| CREBBP | CREB binding protein | 0.0185404 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0182552 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0180971 |
| EXOC6B | exocyst complex component 6B | 0.0179958 |
| BPTF | bromodomain PHD finger transcription factor | 0.0179166 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0178915 |
| RPS27 | ribosomal protein S27 | 0.0178766 |
| RBMX | RNA binding motif protein, X-linked | 0.0177919 |
| RPLP0 | ribosomal protein, large, P0 | 0.0177578 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0176644 |
| CCNI | cyclin I | 0.0175166 |
| SMC6 | structural maintenance of chromosomes 6 | 0.0174669 |
| SERINC1 | serine incorporator 1 | 0.0173664 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0173615 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.017291 |
| VMP1 | vacuole membrane protein 1 | 0.0172248 |
| COL5A2 | collagen, type V, alpha 2 | 0.0171718 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0171307 |
| FBN1 | fibrillin 1 | 0.0170708 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.0170626 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0169049 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0168727 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0168412 |
| SPAG9 | sperm associated antigen 9 | 0.0167963 |
| BRD8 | bromodomain containing 8 | 0.0167866 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0165614 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.016389 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0162914 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0162267 |
| RACK1 | receptor for activated C kinase 1 | 0.0160568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.2751 |
| PEG10 | paternally expressed 10 | -0.226913 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.192282 |
| CADM2 | cell adhesion molecule 2 | -0.168904 |
| MGP | matrix Gla protein | -0.105059 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.104881 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0994886 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0987937 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0962948 |
| PTMA | prothymosin, alpha | -0.0958677 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0932563 |
| MED13L | mediator complex subunit 13-like | -0.0846397 |
| MEOX2 | mesenchyme homeobox 2 | -0.0808597 |
| SEPTIN11 | septin 11 | -0.0791406 |
| ZNF292 | zinc finger protein 292 | -0.0690574 |
| QKI | QKI, KH domain containing, RNA binding | -0.0668124 |
| NFIB | nuclear factor I/B | -0.0665083 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0662278 |
| NFIA | nuclear factor I/A | -0.0644883 |
| SRPK2 | SRSF protein kinase 2 | -0.0642345 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0619759 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0601491 |
| VEGFA | vascular endothelial growth factor A | -0.0596667 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0585413 |
| COL1A2 | collagen, type I, alpha 2 | -0.0546023 |
| KAZN | kazrin, periplakin interacting protein | -0.054431 |
| TMSB10 | thymosin beta 10 | -0.0533381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0524631 |
| MATR3 | matrin 3 | -0.0510171 |
| LDHA | lactate dehydrogenase A | -0.0503372 |
| SPPL3 | signal peptide peptidase like 3 | -0.0500088 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0493469 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0486113 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0483206 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0482917 |
| PDGFC | platelet derived growth factor C | -0.0480392 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0464754 |
| CANX | calnexin | -0.0456139 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0449345 |
| TRERF1 | transcriptional regulating factor 1 | -0.0441687 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0434336 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0434087 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0433985 |
| GOLGA4 | golgin A4 | -0.0432737 |
| ZFHX3 | zinc finger homeobox 3 | -0.0431992 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0416694 |
| MAP1B | microtubule-associated protein 1B | -0.0406501 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0400903 |
| RBM25 | RNA binding motif protein 25 | -0.0400902 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0398987 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0397993 |
| CALD1 | caldesmon 1 | -0.0397667 |
| MSI2 | musashi RNA-binding protein 2 | -0.0396787 |
| YBX1 | Y box binding protein 1 | -0.0389766 |
| PLS3 | plastin 3 | -0.0384032 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0375772 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0367658 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0360906 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0360521 |
| CTBP2 | C-terminal binding protein 2 | -0.0358597 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0358302 |
| CALR | calreticulin | -0.0356443 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0355674 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0352499 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0349523 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0348617 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0347428 |
| PDS5B | PDS5 cohesin associated factor B | -0.0344479 |
| PCM1 | pericentriolar material 1 | -0.0340896 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0339195 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.033832 |
| BCOR | BCL6 corepressor | -0.0337078 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0335377 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0333247 |
| DIPK2A | divergent protein kinase domain 2A | -0.0333048 |
| RREB1 | ras responsive element binding protein 1 | -0.033281 |
| BSG | basigin (Ok blood group) | -0.0331275 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0331186 |
| RNF145 | ring finger protein 145 | -0.0329207 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0327767 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0327456 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0327075 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0324207 |
| RPS24 | ribosomal protein S24 | -0.0320065 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0318179 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0316384 |
| NBEA | neurobeachin | -0.0310486 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0309747 |
| POU2F1 | POU class 2 homeobox 1 | -0.030869 |
| RFX7 | regulatory factor X, 7 | -0.030546 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0301093 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0297966 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0294031 |
| HDLBP | high density lipoprotein binding protein | -0.0293755 |
| GSPT1 | G1 to S phase transition 1 | -0.0291546 |
| S100A9 | S100 calcium binding protein A9 | -0.0288694 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0285677 |
| GSE1 | Gse1 coiled-coil protein | -0.0285604 |
| FBXO11 | F-box protein 11 | -0.0281503 |
| SBF2 | SET binding factor 2 | -0.0278063 |
