| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.127406 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.126782 |
| EXT1 | exostosin glycosyltransferase 1 | 0.122151 |
| TXNRD1 | thioredoxin reductase 1 | 0.11861 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.11226 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.101644 |
| B2M | beta-2-microglobulin | 0.0828911 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0780544 |
| SGMS2 | sphingomyelin synthase 2 | 0.07745 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0733017 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0683829 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0679251 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.066929 |
| MMP1 | matrix metallopeptidase 1 | 0.0608184 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0544457 |
| RPS12 | ribosomal protein S12 | 0.0535747 |
| SIK3 | SIK family kinase 3 | 0.0522512 |
| EFNA5 | ephrin-A5 | 0.0516597 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0510518 |
| BMP6 | bone morphogenetic protein 6 | 0.0489545 |
| RPL37A | ribosomal protein L37a | 0.0470077 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0466436 |
| TGM2 | transglutaminase 2 | 0.0460166 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0452866 |
| RASAL2 | RAS protein activator like 2 | 0.044413 |
| CD44 | CD44 molecule (Indian blood group) | 0.0439973 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0433915 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0430957 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0426249 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0423646 |
| AHR | aryl hydrocarbon receptor | 0.0422183 |
| RPL23 | ribosomal protein L23 | 0.0411299 |
| RPLP2 | ribosomal protein, large, P2 | 0.0403331 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0403261 |
| TXNIP | thioredoxin interacting protein | 0.0398496 |
| CLMP | CXADR-like membrane protein | 0.0394726 |
| FTL | ferritin, light polypeptide | 0.0393287 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0380152 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0379113 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0379072 |
| MYOF | myoferlin | 0.0375643 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0366296 |
| RPS27 | ribosomal protein S27 | 0.036487 |
| ABLIM1 | actin binding LIM protein 1 | 0.03647 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.036229 |
| MED13L | mediator complex subunit 13-like | 0.0359113 |
| GDA | guanine deaminase | 0.0358775 |
| RPS8 | ribosomal protein S8 | 0.0357612 |
| SP100 | SP100 nuclear antigen | 0.035179 |
| RPS3 | ribosomal protein S3 | 0.0351376 |
| FMNL2 | formin-like 2 | 0.0348009 |
| NDRG1 | N-myc downstream regulated 1 | 0.0346304 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0339457 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0337488 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0334905 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.033462 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0330965 |
| KLK10 | kallikrein-related peptidase 10 | 0.0329377 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0327485 |
| TMC5 | transmembrane channel-like 5 | 0.0324297 |
| RPL12 | ribosomal protein L12 | 0.0321079 |
| RPL36 | ribosomal protein L36 | 0.0320951 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.031777 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0317137 |
| HDAC9 | histone deacetylase 9 | 0.0314887 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.031383 |
| RPL8 | ribosomal protein L8 | 0.0312996 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0311249 |
| ERBIN | erbb2 interacting protein | 0.0311096 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0310282 |
| RNF213 | ring finger protein 213 | 0.0304518 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0286286 |
| ASTN2 | astrotactin 2 | 0.0284402 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0282177 |
| RPS17 | ribosomal protein S17 | 0.0279359 |
| SEPTIN9 | septin 9 | 0.0275928 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0275386 |
| PCDH7 | protocadherin 7 | 0.0273581 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0271498 |
| RPL26 | ribosomal protein L26 | 0.0271174 |
| MT2A | metallothionein 2A | 0.0270367 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0268787 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0267014 |
| CRY1 | cryptochrome circadian clock 1 | 0.0265905 |
| RPL31 | ribosomal protein L31 | 0.0263562 |
| CREBBP | CREB binding protein | 0.0263263 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0262658 |
| RPS15 | ribosomal protein S15 | 0.0257415 |
| RPL37 | ribosomal protein L37 | 0.0254126 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.025242 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0252359 |
| RPS29 | ribosomal protein S29 | 0.0251794 |
| RPS2 | ribosomal protein S2 | 0.0250539 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0249877 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0249801 |
| SON | SON DNA binding protein | 0.0249697 |
| WWC1 | WW and C2 domain containing 1 | 0.0248992 |
| RPS21 | ribosomal protein S21 | 0.0245616 |
| LCN2 | lipocalin 2 | 0.0243582 |
| RPS23 | ribosomal protein S23 | 0.0243169 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.147479 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.141422 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.137188 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.131226 |
| FLNB | filamin B, beta | -0.125522 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.111597 |
| PTMA | prothymosin, alpha | -0.105092 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.104795 |
| LAMB3 | laminin, beta 3 | -0.103737 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0973402 |
| VCAN | versican | -0.076014 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0752911 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0727387 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0716221 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0630359 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0614285 |
| AHNAK | AHNAK nucleoprotein | -0.0610189 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0585278 |
| PERP | PERP, TP53 apoptosis effector | -0.0578147 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.056712 |
| NPSR1 | neuropeptide S receptor 1 | -0.0558858 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0548344 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0520525 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0517453 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0515172 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0491802 |
| KRT18 | keratin 18, type I | -0.0479542 |
| FOXO3 | forkhead box O3 | -0.0472513 |
| TPM4 | tropomyosin 4 | -0.0469096 |
| S100A4 | S100 calcium binding protein A4 | -0.0458215 |
| SDC4 | syndecan 4 | -0.0454671 |
| USP53 | ubiquitin specific peptidase 53 | -0.0451241 |
| EZR | ezrin | -0.0444815 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0428275 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0426707 |
| ACTG1 | actin gamma 1 | -0.0423653 |
| ITGB4 | integrin, beta 4 | -0.0418076 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0417639 |
| FOSL1 | FOS-like antigen 1 | -0.0417538 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0414595 |
| OGA | O-GlcNAcase | -0.0411458 |
| BCL2L1 | BCL2-like 1 | -0.0408688 |
| WASF2 | WAS protein family, member 2 | -0.0408372 |
| LAMA4 | laminin, alpha 4 | -0.0403053 |
| VCL | vinculin | -0.0401643 |
| MUC17 | mucin 17, cell surface associated | -0.0401356 |
| SMC3 | structural maintenance of chromosomes 3 | -0.03924 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0383919 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0382636 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0382094 |
| EPHA2 | EPH receptor A2 | -0.0380108 |
| LDHA | lactate dehydrogenase A | -0.0379179 |
| EGFR | epidermal growth factor receptor | -0.0378511 |
| SLMAP | sarcolemma associated protein | -0.0376366 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0375351 |
| PGK1 | phosphoglycerate kinase 1 | -0.0373747 |
| CAPRIN2 | caprin family member 2 | -0.0369192 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0362977 |
| POTEF | POTE ankyrin domain family, member F | -0.0362146 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0355879 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0354744 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0343179 |
| ASPH | aspartate beta-hydroxylase | -0.0342912 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0340645 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336798 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0336047 |
| FAM3C | family with sequence similarity 3, member C | -0.0334323 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0329633 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0328783 |
| DSG2 | desmoglein 2 | -0.0325835 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0325028 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320111 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.031911 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0313003 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0306953 |
| ITGA6 | integrin, alpha 6 | -0.0304275 |
| MCU | mitochondrial calcium uniporter | -0.0303451 |
| PLEC | plectin | -0.0301582 |
| CD2AP | CD2-associated protein | -0.0300375 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0299451 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0294745 |
| CANX | calnexin | -0.0293784 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0289537 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0289364 |
| KRT8 | keratin 8, type II | -0.0288999 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0286293 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0286233 |
| EGR1 | early growth response 1 | -0.028613 |
| RCOR1 | REST corepressor 1 | -0.0284168 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0284068 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0278359 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0277946 |
| OPTN | optineurin | -0.027548 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0274503 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.027443 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0274218 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0272387 |
| THOC2 | THO complex 2 | -0.0270384 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0268012 |
| FAM107B | family with sequence similarity 107, member B | -0.0267453 |
