| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.14337 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.130503 |
| JMJD1C | jumonji domain containing 1C | 0.124818 |
| ZNF608 | zinc finger protein 608 | 0.123713 |
| RPS6 | ribosomal protein S6 | 0.115365 |
| RPS12 | ribosomal protein S12 | 0.0934735 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0926643 |
| TOX | thymocyte selection-associated high mobility group box | 0.0818372 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0797253 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.075376 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0734366 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.071857 |
| RPS8 | ribosomal protein S8 | 0.0717736 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0684952 |
| RPS3 | ribosomal protein S3 | 0.0668878 |
| NFIA | nuclear factor I/A | 0.0659382 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0626125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0624338 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0613326 |
| RPL37A | ribosomal protein L37a | 0.0605889 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.060003 |
| RPS2 | ribosomal protein S2 | 0.0590783 |
| NBEAL1 | neurobeachin-like 1 | 0.0581069 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0573698 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0567086 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0565739 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0553831 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0549604 |
| ZNF292 | zinc finger protein 292 | 0.0529222 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0528984 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0515179 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0502462 |
| RPL11 | ribosomal protein L11 | 0.0498854 |
| CCDC88A | coiled-coil domain containing 88A | 0.0497561 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0492019 |
| DSCAM | Down syndrome cell adhesion molecule | 0.049095 |
| RPL18 | ribosomal protein L18 | 0.04906 |
| SIK3 | SIK family kinase 3 | 0.0481184 |
| PHIP | pleckstrin homology domain interacting protein | 0.0477591 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0471978 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0469606 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0468108 |
| ZNF638 | zinc finger protein 638 | 0.0467294 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0463149 |
| DST | dystonin | 0.0460327 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0457924 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0454902 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0445171 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0436356 |
| RPS17 | ribosomal protein S17 | 0.0435378 |
| NFIB | nuclear factor I/B | 0.0433775 |
| RPL26 | ribosomal protein L26 | 0.0423329 |
| RPL7 | ribosomal protein L7 | 0.0420845 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0414997 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0413821 |
| OGA | O-GlcNAcase | 0.0413195 |
| BNC2 | basonuclin 2 | 0.0408732 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0404166 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0402421 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0399022 |
| RPL36 | ribosomal protein L36 | 0.0397904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0395644 |
| SET | SET nuclear proto-oncogene | 0.0384182 |
| RIGI | RNA sensor RIG-I | 0.038209 |
| USP34 | ubiquitin specific peptidase 34 | 0.0376753 |
| HOMER1 | homer scaffolding protein 1 | 0.0373153 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0370598 |
| RACK1 | receptor for activated C kinase 1 | 0.0370486 |
| GNAS | GNAS complex locus | 0.0370116 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0367171 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0365507 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0364292 |
| MKI67 | marker of proliferation Ki-67 | 0.0360093 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0356146 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355048 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0355013 |
| MED13 | mediator complex subunit 13 | 0.0354462 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0353867 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0347895 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0343688 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.034104 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0338802 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0337683 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0336808 |
| ATG10 | autophagy related 10 | 0.0335857 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0332891 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0332631 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0329539 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0325338 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0323537 |
| RPS29 | ribosomal protein S29 | 0.0322759 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0319111 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0314843 |
| FBXO11 | F-box protein 11 | 0.03112 |
| BPTF | bromodomain PHD finger transcription factor | 0.0310839 |
| SYAP1 | synapse associated protein 1 | 0.0309698 |
| NKTR | natural killer cell triggering receptor | 0.0308247 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306944 |
| B2M | beta-2-microglobulin | 0.0306658 |
| SIK2 | salt-inducible kinase 2 | 0.0303398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.210978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.166953 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117842 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0873 |
| PTMA | prothymosin, alpha | -0.0467029 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.046636 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0455277 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0446023 |
| FMNL2 | formin-like 2 | -0.0393614 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384604 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0375803 |
| NEBL | nebulette | -0.0363637 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0358478 |
| CANX | calnexin | -0.0342552 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0341301 |
| TMSB10 | thymosin beta 10 | -0.0324978 |
| FAT1 | FAT atypical cadherin 1 | -0.0323455 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0322367 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0318237 |
| RPS24 | ribosomal protein S24 | -0.0315031 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291641 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0290145 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0289005 |
| EMP1 | epithelial membrane protein 1 | -0.0285359 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0282122 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0281029 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0278045 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0263788 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0261084 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0260468 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0248399 |
| HMGA2 | high mobility group AT-hook 2 | -0.0243959 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0243433 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0241702 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0232776 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.023176 |
| TXNRD1 | thioredoxin reductase 1 | -0.0225329 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0220933 |
| CALR | calreticulin | -0.0220732 |
| FN1 | fibronectin 1 | -0.0213252 |
| VIM | vimentin | -0.0212812 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0212793 |
| UBE3C | ubiquitin protein ligase E3C | -0.0212232 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0211506 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0211419 |
| ZNF544 | zinc finger protein 544 | -0.0209775 |
| RPL27A | ribosomal protein L27a | -0.0206789 |
| DENND1A | DENN/MADD domain containing 1A | -0.0206242 |
| HMGB1 | high mobility group box 1 | -0.0204914 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0204248 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0204047 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0203868 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0202906 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0200487 |
| ZFP64 | ZFP64 zinc finger protein | -0.0198271 |
| MTAP | methylthioadenosine phosphorylase | -0.019173 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0191403 |
| ZNF770 | zinc finger protein 770 | -0.0189711 |
| PYGL | phosphorylase, glycogen, liver | -0.0188617 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0187834 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0187821 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0186012 |
| METTL2B | methyltransferase like 2B | -0.0185663 |
| FASN | fatty acid synthase | -0.0185531 |
| ZNF217 | zinc finger protein 217 | -0.018369 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0183571 |
| RPL6 | ribosomal protein L6 | -0.0179374 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0179199 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.0177967 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.0176651 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0174406 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0174322 |
| TRAP1 | TNF receptor-associated protein 1 | -0.0174032 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0173692 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0172904 |
| FBL | fibrillarin | -0.0171085 |
| VMA21 | VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) | -0.0170694 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0167906 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0166257 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0166185 |
| BRI3BP | BRI3 binding protein | -0.016618 |
| ARF1 | ADP-ribosylation factor 1 | -0.0165665 |
| CPA6 | carboxypeptidase A6 | -0.0165102 |
| ZNF33A | zinc finger protein 33A | -0.0159633 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0158024 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.015759 |
| NINL | ninein-like | -0.0156516 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0155807 |
| GSE1 | Gse1 coiled-coil protein | -0.015525 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0154093 |
| NPR2 | natriuretic peptide receptor 2 | -0.0153826 |
| CALU | calumenin | -0.015307 |
| C1QBP | complement component 1, q subcomponent binding protein | -0.0152799 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0152336 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0151035 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0150638 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | -0.014905 |
| SALL4 | spalt-like transcription factor 4 | -0.0148026 |
| PDCD11 | programmed cell death 11 | -0.0147973 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0147026 |
