| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.204351 |
| GPC6 | glypican 6 | 0.145941 |
| VIM | vimentin | 0.136945 |
| FMN1 | formin 1 | 0.12032 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0905571 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0883827 |
| MT2A | metallothionein 2A | 0.0783342 |
| ACTG1 | actin gamma 1 | 0.0782415 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0774146 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0751215 |
| FRMD4A | FERM domain containing 4A | 0.0479967 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0457767 |
| PTCHD4 | patched domain containing 4 | 0.0416075 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0401628 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0384055 |
| EXOC4 | exocyst complex component 4 | 0.0382192 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0376599 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0361279 |
| NPC1 | Niemann-Pick disease, type C1 | 0.035326 |
| SFTPA2 | surfactant protein A2 | 0.034539 |
| VCL | vinculin | 0.0341795 |
| RPS12 | ribosomal protein S12 | 0.0338156 |
| NAV1 | neuron navigator 1 | 0.0336832 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0325326 |
| SETBP1 | SET binding protein 1 | 0.0323475 |
| EHBP1 | EH domain binding protein 1 | 0.0319731 |
| NAV3 | neuron navigator 3 | 0.0309027 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0307426 |
| ENO1 | enolase 1, (alpha) | 0.029957 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0285819 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0281436 |
| TLE4 | transducin-like enhancer of split 4 | 0.0269731 |
| RPS8 | ribosomal protein S8 | 0.0265611 |
| PAX3 | paired box 3 | 0.0256351 |
| ACTN1 | actinin, alpha 1 | 0.0255152 |
| DST | dystonin | 0.0254508 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0252973 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0245034 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0244147 |
| PCDH7 | protocadherin 7 | 0.0243613 |
| BPTF | bromodomain PHD finger transcription factor | 0.0242289 |
| TRIM9 | tripartite motif containing 9 | 0.023973 |
| B2M | beta-2-microglobulin | 0.0238776 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0237048 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0235158 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0234946 |
| RPL37A | ribosomal protein L37a | 0.0234758 |
| INTS6 | integrator complex subunit 6 | 0.0232598 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0230918 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0228249 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0224954 |
| HMGA2 | high mobility group AT-hook 2 | 0.0220698 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0218282 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0216765 |
| AHNAK | AHNAK nucleoprotein | 0.0213019 |
| SMYD3 | SET and MYND domain containing 3 | 0.0210773 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0207664 |
| SQSTM1 | sequestosome 1 | 0.0206914 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.020673 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0204974 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0204548 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0202998 |
| RPS3 | ribosomal protein S3 | 0.0200795 |
| POTEF | POTE ankyrin domain family, member F | 0.0200444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0198341 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0197161 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0196964 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0195988 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.01958 |
| SHISA5 | shisa family member 5 | 0.0195783 |
| RO60 | Ro60, Y RNA binding protein | 0.0194988 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0192116 |
| AEBP2 | AE binding protein 2 | 0.0191325 |
| NRP2 | neuropilin 2 | 0.019028 |
| LYST | lysosomal trafficking regulator | 0.0188459 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0188413 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0188145 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0186232 |
| IL6ST | interleukin 6 signal transducer | 0.0186205 |
| MTPN | myotrophin | 0.0184973 |
| UTRN | utrophin | 0.0184461 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0183548 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0181363 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0180682 |
| ATXN7L1 | ataxin 7-like 1 | 0.017831 |
| MED13L | mediator complex subunit 13-like | 0.0177754 |
| MITF | microphthalmia-associated transcription factor | 0.0176981 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0175515 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0175149 |
| SHROOM4 | shroom family member 4 | 0.0173577 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0172282 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | 0.0171676 |
| TNRC6B | trinucleotide repeat containing 6B | 0.017154 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 | 0.0170478 |
| GPHN | gephyrin | 0.0170429 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0170406 |
| CYTH3 | cytohesin 3 | 0.016977 |
| EXOC6B | exocyst complex component 6B | 0.016946 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | 0.0169364 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0167513 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181615 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.152922 |
| VGF | VGF nerve growth factor inducible | -0.129578 |
| NDRG1 | N-myc downstream regulated 1 | -0.125245 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.124437 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.083335 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0801608 |
| CD109 | CD109 molecule | -0.0787167 |
| TAC4 | tachykinin 4 (hemokinin) | -0.074263 |
| NBAS | neuroblastoma amplified sequence | -0.0699563 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0666082 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0659035 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0642859 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0628873 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0596924 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0568037 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0566899 |
| COPA | coatomer protein complex, subunit alpha | -0.0560103 |
| NUP58 | nucleoporin 58 | -0.0539057 |
| PHF21A | PHD finger protein 21A | -0.053549 |
| CDC73 | cell division cycle 73 | -0.0533837 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0523653 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0514118 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0509111 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0494881 |
| RNF145 | ring finger protein 145 | -0.0476106 |
| PTK2 | protein tyrosine kinase 2 | -0.0474394 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0470336 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0466719 |
| WDR45B | WD repeat domain 45B | -0.0454756 |
| FMNL2 | formin-like 2 | -0.0452295 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0445521 |
| GOLGA4 | golgin A4 | -0.0443998 |
| CALU | calumenin | -0.0442254 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0434243 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0424743 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0423258 |
| MEF2A | myocyte enhancer factor 2A | -0.0413546 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0410868 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0407967 |
| RNF24 | ring finger protein 24 | -0.0406376 |
| CABIN1 | calcineurin binding protein 1 | -0.0401358 |
| CALR | calreticulin | -0.0393144 |
| NPR2 | natriuretic peptide receptor 2 | -0.0385212 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0377503 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0371169 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0369938 |
| ZNF292 | zinc finger protein 292 | -0.036244 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0360616 |
| FOSL1 | FOS-like antigen 1 | -0.0354465 |
| GDF15 | growth differentiation factor 15 | -0.0351983 |
| TBC1D22A | TBC1 domain family, member 22A | -0.034987 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0341304 |
| CANX | calnexin | -0.0333362 |
| NLGN1 | neuroligin 1 | -0.0330294 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329409 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0329375 |
| INSIG1 | insulin induced gene 1 | -0.0326116 |
| RFX7 | regulatory factor X, 7 | -0.0325736 |
| TMEM123 | transmembrane protein 123 | -0.03237 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0322131 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0321842 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0318862 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0317163 |
| PYGB | phosphorylase, glycogen; brain | -0.0316824 |
| HELZ | helicase with zinc finger | -0.0313807 |
| FAM162A | family with sequence similarity 162, member A | -0.0302883 |
| INSIG2 | insulin induced gene 2 | -0.0291826 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0290367 |
| POM121 | POM121 transmembrane nucleoporin | -0.0288959 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0286143 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0281341 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0280576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0279612 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270179 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0267741 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0262635 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0261704 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0257425 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0255593 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0248503 |
| SSH1 | slingshot protein phosphatase 1 | -0.0248207 |
| USP3 | ubiquitin specific peptidase 3 | -0.0236721 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0230332 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0229741 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0229437 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.022871 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0228274 |
| FOXJ3 | forkhead box J3 | -0.0227844 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0227192 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.022598 |
| SETD5 | SET domain containing 5 | -0.0224886 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0223434 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0221842 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0219435 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0219409 |
| TAGLN2 | transgelin 2 | -0.0218683 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0217371 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0213438 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0211709 |
