| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.139426 |
| B2M | beta-2-microglobulin | 0.121455 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.121446 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.105944 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.105632 |
| APOL1 | apolipoprotein L, 1 | 0.105384 |
| HLA-B | major histocompatibility complex, class I, B | 0.103711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.096913 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0937971 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0767228 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0759139 |
| RPS8 | ribosomal protein S8 | 0.0752874 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0727971 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0704105 |
| CP | ceruloplasmin (ferroxidase) | 0.0703126 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0693239 |
| RNF213 | ring finger protein 213 | 0.0679839 |
| KYNU | kynureninase | 0.0671154 |
| NRG3 | neuregulin 3 | 0.0646809 |
| ENO1 | enolase 1, (alpha) | 0.0643628 |
| EFNA5 | ephrin-A5 | 0.0633771 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0633734 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.062339 |
| SP100 | SP100 nuclear antigen | 0.0620236 |
| RPL23 | ribosomal protein L23 | 0.0617743 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0592614 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0591703 |
| PTMA | prothymosin, alpha | 0.0567568 |
| HLA-E | major histocompatibility complex, class I, E | 0.0560251 |
| VIM | vimentin | 0.0552381 |
| RPS3 | ribosomal protein S3 | 0.0551891 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0545854 |
| RPL19 | ribosomal protein L19 | 0.0511767 |
| MMP7 | matrix metallopeptidase 7 | 0.051125 |
| RPLP1 | ribosomal protein, large, P1 | 0.0509445 |
| RPL37A | ribosomal protein L37a | 0.0508874 |
| MT1E | metallothionein 1E | 0.0493555 |
| KRT19 | keratin 19, type I | 0.049243 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0479426 |
| MX1 | MX dynamin-like GTPase 1 | 0.0476704 |
| RAD51B | RAD51 paralog B | 0.0476238 |
| RPS6 | ribosomal protein S6 | 0.0472949 |
| HDAC9 | histone deacetylase 9 | 0.0465151 |
| MX2 | MX dynamin-like GTPase 2 | 0.0460802 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0450496 |
| TMC5 | transmembrane channel-like 5 | 0.0448022 |
| SQSTM1 | sequestosome 1 | 0.0446892 |
| LCN2 | lipocalin 2 | 0.0443907 |
| RPS29 | ribosomal protein S29 | 0.044139 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0440864 |
| KLF6 | Kruppel-like factor 6 | 0.0431137 |
| LAMB3 | laminin, beta 3 | 0.0429563 |
| RPL34 | ribosomal protein L34 | 0.0425806 |
| FTL | ferritin, light polypeptide | 0.04182 |
| CFB | complement factor B | 0.0410136 |
| RPL35A | ribosomal protein L35a | 0.0406642 |
| PMP22 | peripheral myelin protein 22 | 0.0405036 |
| MYOF | myoferlin | 0.0404294 |
| RPS27A | ribosomal protein S27a | 0.0403227 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0397748 |
| RACK1 | receptor for activated C kinase 1 | 0.0387564 |
| AHNAK | AHNAK nucleoprotein | 0.0386364 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0385892 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0382449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0381145 |
| ASPH | aspartate beta-hydroxylase | 0.0380953 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0380652 |
| RPL37 | ribosomal protein L37 | 0.0379102 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0376322 |
| RPL11 | ribosomal protein L11 | 0.0372889 |
| RPS12 | ribosomal protein S12 | 0.0370555 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0370547 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.03697 |
| UBC | ubiquitin C | 0.036778 |
| NTN4 | netrin 4 | 0.0362826 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0362498 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0353869 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0348519 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0347853 |
| RPL31 | ribosomal protein L31 | 0.0345477 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0344958 |
| CANX | calnexin | 0.0342402 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0339576 |
| RPL12 | ribosomal protein L12 | 0.0336908 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335676 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0334413 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0323946 |
| RPS25 | ribosomal protein S25 | 0.0320645 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0319938 |
| RPLP0 | ribosomal protein, large, P0 | 0.0313055 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0312791 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0309255 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0307698 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0307326 |
| HKDC1 | hexokinase domain containing 1 | 0.0304456 |
| PCDH7 | protocadherin 7 | 0.0304172 |
| RPS24 | ribosomal protein S24 | 0.0302753 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0299941 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0299501 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0299421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | -0.101836 |
| SPAG9 | sperm associated antigen 9 | -0.0830192 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.079498 |
| DTNA | dystrobrevin, alpha | -0.0709613 |
| POTEF | POTE ankyrin domain family, member F | -0.0639336 |
| NDRG1 | N-myc downstream regulated 1 | -0.0635138 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0554803 |
| MEF2A | myocyte enhancer factor 2A | -0.0530821 |
| CCNL1 | cyclin L1 | -0.0487456 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0483638 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0483095 |
| GRB10 | growth factor receptor-bound protein 10 | -0.046642 |
| RTN4 | reticulon 4 | -0.04653 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0465032 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0453503 |
| CCNY | cyclin Y | -0.0442674 |
| FLNB | filamin B, beta | -0.0423462 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0413863 |
| MCU | mitochondrial calcium uniporter | -0.0412926 |
| RCOR1 | REST corepressor 1 | -0.0412576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0392292 |
| FAM13A | family with sequence similarity 13, member A | -0.0379765 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0363322 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0354493 |
| NUP58 | nucleoporin 58 | -0.0353109 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0347396 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0346892 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0346643 |
| JUP | junction plakoglobin | -0.0343031 |
| ABI1 | abl-interactor 1 | -0.0342679 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0337472 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0337111 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0329368 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.032862 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.032442 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0317735 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0315028 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0308328 |
| FOSL1 | FOS-like antigen 1 | -0.0308297 |
| ZNF292 | zinc finger protein 292 | -0.030407 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0295653 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0294839 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0294374 |
| NPTN | neuroplastin | -0.0289194 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0285882 |
| LMO7 | LIM domain 7 | -0.0284677 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0282953 |
| HELZ | helicase with zinc finger | -0.0281354 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0277784 |
| PARD3 | par-3 family cell polarity regulator | -0.0275841 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0271117 |
| VEGFA | vascular endothelial growth factor A | -0.0268039 |
| AGRN | agrin | -0.0265682 |
| LAMA5 | laminin, alpha 5 | -0.025962 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0258986 |
| SEC24A | SEC24 family member A | -0.0253171 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0246232 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0246199 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0246154 |
| MYO5B | myosin VB | -0.0246117 |
| EGR1 | early growth response 1 | -0.0241497 |
| PLS3 | plastin 3 | -0.0238687 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0237093 |
| DIAPH1 | diaphanous-related formin 1 | -0.0236633 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0234174 |
| USP3 | ubiquitin specific peptidase 3 | -0.0233104 |
| MAP1B | microtubule-associated protein 1B | -0.0225938 |
| RLF | rearranged L-myc fusion | -0.0223577 |
| ITGB4 | integrin, beta 4 | -0.0220806 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0219787 |
| TFG | TRK-fused gene | -0.0218921 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.021797 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0215968 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0214782 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0213467 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.021346 |
| BRD2 | bromodomain containing 2 | -0.0212658 |
| CDC73 | cell division cycle 73 | -0.0210311 |
| FOXO3 | forkhead box O3 | -0.0209296 |
| ATP11B | ATPase, class VI, type 11B | -0.0207657 |
| INSIG1 | insulin induced gene 1 | -0.0206316 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0205854 |
| FAM162A | family with sequence similarity 162, member A | -0.0201716 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0195127 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0192481 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0188994 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.018844 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0187683 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0186159 |
| MYO1B | myosin IB | -0.0182628 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0182093 |
| YTHDC1 | YTH domain containing 1 | -0.0180594 |
| FNBP1L | formin binding protein 1-like | -0.0179198 |
| MXD1 | MAX dimerization protein 1 | -0.0175711 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0175474 |
| ZNF654 | zinc finger protein 654 | -0.0174796 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0173999 |
| TAGLN2 | transgelin 2 | -0.0172343 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0171278 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0170345 |
