| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.161159 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.139828 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.128717 |
| RNF213 | ring finger protein 213 | 0.12564 |
| SMAD3 | SMAD family member 3 | 0.117444 |
| SP100 | SP100 nuclear antigen | 0.114012 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.113246 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.10734 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.107138 |
| EXT1 | exostosin glycosyltransferase 1 | 0.105795 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0993987 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.096142 |
| ERBIN | erbb2 interacting protein | 0.090256 |
| MAP7 | microtubule-associated protein 7 | 0.0835319 |
| AREG | amphiregulin | 0.0830502 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0809316 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0777605 |
| ZNF292 | zinc finger protein 292 | 0.0734032 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0729929 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.068438 |
| BCL2L1 | BCL2-like 1 | 0.0684243 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0681362 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0678168 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0672885 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0668661 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0661036 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0626835 |
| LCN2 | lipocalin 2 | 0.0588144 |
| MX2 | MX dynamin-like GTPase 2 | 0.0580729 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0569744 |
| DST | dystonin | 0.056511 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0564517 |
| XAF1 | XIAP associated factor 1 | 0.0563722 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0555497 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0553242 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0548694 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0546893 |
| ANXA2 | annexin A2 | 0.0541163 |
| TJP1 | tight junction protein 1 | 0.0535678 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0533646 |
| ASPH | aspartate beta-hydroxylase | 0.0528987 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0527381 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0516081 |
| MX1 | MX dynamin-like GTPase 1 | 0.0513575 |
| FNIP1 | folliculin interacting protein 1 | 0.0496165 |
| YAP1 | Yes-associated protein 1 | 0.0488863 |
| RIGI | RNA sensor RIG-I | 0.0485771 |
| RAD51B | RAD51 paralog B | 0.0482565 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0481484 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0459058 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0458706 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0456352 |
| ETV6 | ets variant 6 | 0.0455148 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0450331 |
| ACTG1 | actin gamma 1 | 0.044808 |
| HKDC1 | hexokinase domain containing 1 | 0.044712 |
| KYNU | kynureninase | 0.0446176 |
| EFNB2 | ephrin-B2 | 0.0441712 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0441544 |
| PLSCR2 | phospholipid scramblase 2 | 0.0438925 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0437538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0429386 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0416797 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.040822 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0407608 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0406299 |
| INTS6 | integrator complex subunit 6 | 0.0399728 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0386826 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0384214 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0381614 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0376694 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0370286 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0358254 |
| UBAP2 | ubiquitin associated protein 2 | 0.0356969 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0353754 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0351321 |
| NABP1 | nucleic acid binding protein 1 | 0.0351039 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0350495 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0348687 |
| SMYD3 | SET and MYND domain containing 3 | 0.0346631 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0343726 |
| WWOX | WW domain containing oxidoreductase | 0.0343415 |
| FHIT | fragile histidine triad | 0.0342268 |
| MYO5B | myosin VB | 0.0332826 |
| SPAG9 | sperm associated antigen 9 | 0.0332553 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0322222 |
| PERP | PERP, TP53 apoptosis effector | 0.0319525 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.031534 |
| EREG | epiregulin | 0.0310301 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0309771 |
| PLSCR1 | phospholipid scramblase 1 | 0.03082 |
| NF1 | neurofibromin 1 | 0.0306013 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0306008 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0303391 |
| JMJD1C | jumonji domain containing 1C | 0.0303331 |
| RPS6 | ribosomal protein S6 | 0.0303016 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0300566 |
| EXOC4 | exocyst complex component 4 | 0.0300514 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0300248 |
| JAK1 | Janus kinase 1 | 0.0299039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164584 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.120659 |
| NDRG1 | N-myc downstream regulated 1 | -0.10419 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0996002 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0842297 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0762436 |
| B2M | beta-2-microglobulin | -0.0602869 |
| EGR1 | early growth response 1 | -0.0527555 |
| IRF1 | interferon regulatory factor 1 | -0.050818 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0503854 |
| CALR | calreticulin | -0.0497845 |
| EZR | ezrin | -0.0495367 |
| MORF4L2 | mortality factor 4 like 2 | -0.0491858 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0490949 |
| H1-0 | H1.0 linker histone | -0.0487762 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0487006 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0470567 |
| TXNIP | thioredoxin interacting protein | -0.0447859 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0429605 |
| GOLGB1 | golgin B1 | -0.0426819 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0414026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0400315 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.039334 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.039106 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0385889 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0380335 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0379938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0378786 |
| COG6 | component of oligomeric golgi complex 6 | -0.0368987 |
| AHI1 | Abelson helper integration site 1 | -0.0367481 |
| TRIM2 | tripartite motif containing 2 | -0.036404 |
| CDHR2 | cadherin-related family member 2 | -0.0359615 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0350934 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0342229 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0339927 |
| RRBP1 | ribosome binding protein 1 | -0.0338763 |
| HDLBP | high density lipoprotein binding protein | -0.0330655 |
| ABHD2 | abhydrolase domain containing 2 | -0.0324659 |
| PER2 | period circadian clock 2 | -0.0315239 |
| WDR45B | WD repeat domain 45B | -0.0313061 |
| PTEN | phosphatase and tensin homolog | -0.0309372 |
| ADIPOR2 | adiponectin receptor 2 | -0.0306428 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0303552 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0301531 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0299805 |
| AGR2 | anterior gradient 2 | -0.0285189 |
| VEGFA | vascular endothelial growth factor A | -0.0282405 |
| FDPS | farnesyl diphosphate synthase | -0.0277864 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0275331 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271641 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0270163 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0260602 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0260051 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0254491 |
| ANXA1 | annexin A1 | -0.0253213 |
| CCNL1 | cyclin L1 | -0.0252231 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0250233 |
| S100A6 | S100 calcium binding protein A6 | -0.0245081 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0239223 |
| PKM | pyruvate kinase, muscle | -0.0238154 |
| ARF4 | ADP-ribosylation factor 4 | -0.0235732 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0235558 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0234363 |
| INSIG1 | insulin induced gene 1 | -0.0233517 |
| SEC24A | SEC24 family member A | -0.0232841 |
| DIAPH3 | diaphanous-related formin 3 | -0.0231215 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0230423 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0230029 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0226787 |
| AFF1 | AF4/FMR2 family, member 1 | -0.022566 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0225287 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0224526 |
| SEC24D | SEC24 family member D | -0.0222862 |
| ERCC5 | excision repair cross-complementation group 5 | -0.0221071 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0220087 |
| USP3 | ubiquitin specific peptidase 3 | -0.0219879 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0219604 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0217182 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0216386 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.021461 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0213084 |
| A1CF | APOBEC1 complementation factor | -0.0211359 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0210088 |
| MEIS2 | Meis homeobox 2 | -0.0209959 |
| ETNK1 | ethanolamine kinase 1 | -0.0209656 |
| WASF2 | WAS protein family, member 2 | -0.0208268 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0207738 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0206856 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0205798 |
| CLDN7 | claudin 7 | -0.0205776 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0205351 |
| COPA | coatomer protein complex, subunit alpha | -0.0203128 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0203078 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.020227 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0202145 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0201714 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.020045 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0199396 |
| NUCB2 | nucleobindin 2 | -0.0197452 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0195697 |
