| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.288285 |
| CD44 | CD44 molecule (Indian blood group) | 0.136832 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0953482 |
| ENO1 | enolase 1, (alpha) | 0.0708614 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0702884 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0649799 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0540862 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0521495 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0514049 |
| LDHA | lactate dehydrogenase A | 0.0446153 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0444811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0437508 |
| FN1 | fibronectin 1 | 0.0431323 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0424194 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.039535 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0384401 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0364587 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0330352 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0320592 |
| STC1 | stanniocalcin 1 | 0.0318495 |
| TPI1 | triosephosphate isomerase 1 | 0.0314772 |
| TXNIP | thioredoxin interacting protein | 0.0311905 |
| AHNAK | AHNAK nucleoprotein | 0.0300535 |
| MAP1B | microtubule-associated protein 1B | 0.0300223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0290869 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0289494 |
| SYAP1 | synapse associated protein 1 | 0.0289179 |
| IGF2 | insulin-like growth factor 2 | 0.0282222 |
| DST | dystonin | 0.0278136 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0271986 |
| GLIS3 | GLIS family zinc finger 3 | 0.0265083 |
| ANXA2 | annexin A2 | 0.0259893 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252345 |
| RPL12 | ribosomal protein L12 | 0.0248901 |
| LOX | lysyl oxidase | 0.0247003 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0244955 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.024288 |
| AXL | AXL receptor tyrosine kinase | 0.0242401 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0235882 |
| MT2A | metallothionein 2A | 0.0235274 |
| TUBB | tubulin, beta class I | 0.0234432 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.023307 |
| CDCP1 | CUB domain containing protein 1 | 0.022093 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0219822 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0212299 |
| INHBA | inhibin, beta A | 0.0208923 |
| MSN | moesin | 0.020794 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0206943 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0203833 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0202812 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0201975 |
| TNNC1 | troponin C type 1 (slow) | 0.0199526 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0197828 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0196995 |
| TENM2 | teneurin transmembrane protein 2 | 0.0194568 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0194445 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.01909 |
| NF1 | neurofibromin 1 | 0.0190631 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0187608 |
| DNMBP | dynamin binding protein | 0.0183625 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0183259 |
| RNF24 | ring finger protein 24 | 0.0179146 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0177351 |
| MKI67 | marker of proliferation Ki-67 | 0.017657 |
| RPS12 | ribosomal protein S12 | 0.0176295 |
| CEP112 | centrosomal protein 112kDa | 0.0173882 |
| PRSS23 | protease, serine, 23 | 0.0171759 |
| RPL7 | ribosomal protein L7 | 0.0171671 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.016971 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0164896 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0164068 |
| MT1X | metallothionein 1X | 0.0163592 |
| MYO10 | myosin X | 0.0163179 |
| YBX3 | Y box binding protein 3 | 0.0160501 |
| RND3 | Rho family GTPase 3 | 0.0159437 |
| SON | SON DNA binding protein | 0.0159435 |
| SMAD3 | SMAD family member 3 | 0.0159416 |
| RPS2 | ribosomal protein S2 | 0.0158691 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0157088 |
| CENPF | centromere protein F, 350/400kDa | 0.015676 |
| CLTC | clathrin, heavy chain (Hc) | 0.0155767 |
| RPL32 | ribosomal protein L32 | 0.015456 |
| NAV1 | neuron navigator 1 | 0.0154545 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0154015 |
| TAGLN2 | transgelin 2 | 0.0153869 |
| SET | SET nuclear proto-oncogene | 0.0151738 |
| VEGFC | vascular endothelial growth factor C | 0.0149159 |
| VCL | vinculin | 0.0148892 |
| DIAPH3 | diaphanous-related formin 3 | 0.0148674 |
| TPX2 | TPX2, microtubule-associated | 0.0148389 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0148257 |
| PFN1 | profilin 1 | 0.0146951 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0144944 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0142721 |
| RPL8 | ribosomal protein L8 | 0.0137369 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0137119 |
| CALU | calumenin | 0.0137101 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0135824 |
| WWOX | WW domain containing oxidoreductase | 0.0135784 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0134489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119313 |
| PTMA | prothymosin, alpha | -0.118135 |
| CDH13 | cadherin 13 | -0.114841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10273 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.102678 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.100613 |
| VIM | vimentin | -0.0995986 |
| ASPH | aspartate beta-hydroxylase | -0.0591938 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0561277 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0518461 |
| RPLP1 | ribosomal protein, large, P1 | -0.0472342 |
| RPL35A | ribosomal protein L35a | -0.0459976 |
| HMGA2 | high mobility group AT-hook 2 | -0.043977 |
| DTNA | dystrobrevin, alpha | -0.0418601 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0410056 |
| RPS24 | ribosomal protein S24 | -0.0359706 |
| IER3 | immediate early response 3 | -0.0353858 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0351012 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0336392 |
| CAVIN1 | caveolae associated protein 1 | -0.0331645 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331082 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0330424 |
| ADM | adrenomedullin | -0.0326815 |
| INTS6 | integrator complex subunit 6 | -0.0323309 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0316896 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0314149 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0311599 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0306597 |
| RPL38 | ribosomal protein L38 | -0.0304578 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296344 |
| TMSB10 | thymosin beta 10 | -0.02867 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0281133 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0279663 |
| RPS27A | ribosomal protein S27a | -0.0274941 |
| LRRC23 | leucine rich repeat containing 23 | -0.0269531 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0261806 |
| RASA3 | RAS p21 protein activator 3 | -0.0261046 |
| EGR1 | early growth response 1 | -0.0251938 |
| RPL31 | ribosomal protein L31 | -0.0251128 |
| RPL23 | ribosomal protein L23 | -0.0247053 |
| COL7A1 | collagen, type VII, alpha 1 | -0.024624 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.024543 |
| FMN1 | formin 1 | -0.0242099 |
| SHISA5 | shisa family member 5 | -0.0238511 |
| HM13 | histocompatibility (minor) 13 | -0.0236059 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0235746 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0232113 |
| MCL1 | myeloid cell leukemia 1 | -0.0228916 |
| RPS16 | ribosomal protein S16 | -0.0223416 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0214769 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0214767 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0206672 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206638 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.020433 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0201855 |
| GOLGA4 | golgin A4 | -0.0200749 |
| FRMD4A | FERM domain containing 4A | -0.0198482 |
| FBXO11 | F-box protein 11 | -0.0197497 |
| HLA-B | major histocompatibility complex, class I, B | -0.0195092 |
| RPS13 | ribosomal protein S13 | -0.0191801 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0188682 |
| COL1A1 | collagen, type I, alpha 1 | -0.0185174 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0184652 |
| NUMB | numb homolog (Drosophila) | -0.0183142 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180162 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0178724 |
| TBCA | tubulin folding cofactor A | -0.0177309 |
| RPS20 | ribosomal protein S20 | -0.0176479 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0174285 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0172867 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0170015 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0168929 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0167385 |
| CMIP | c-Maf inducing protein | -0.0166457 |
| CLMP | CXADR-like membrane protein | -0.0165721 |
| GOLGB1 | golgin B1 | -0.0164754 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0164216 |
| RAD51B | RAD51 paralog B | -0.0162143 |
| ATG7 | autophagy related 7 | -0.0161366 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0159915 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0157313 |
| GPHN | gephyrin | -0.0157203 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0155656 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0153509 |
| RRBP1 | ribosome binding protein 1 | -0.0152571 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0151535 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | -0.0151431 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.0150711 |
| HPCAL1 | hippocalcin-like 1 | -0.0150703 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0150451 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.01498 |
| RPS25 | ribosomal protein S25 | -0.0149535 |
| RPS29 | ribosomal protein S29 | -0.0149269 |
| TNS1 | tensin 1 | -0.0148718 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0148057 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0147378 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0146486 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0145788 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0144977 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0144879 |
