| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.126137 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.1217 |
| NTN4 | netrin 4 | 0.0981674 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0799836 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0794421 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0758382 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0663912 |
| AHNAK | AHNAK nucleoprotein | 0.0663273 |
| MKI67 | marker of proliferation Ki-67 | 0.0627931 |
| RPS6 | ribosomal protein S6 | 0.0616897 |
| FTL | ferritin, light polypeptide | 0.0609197 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0606755 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0563028 |
| BCL2L1 | BCL2-like 1 | 0.0560864 |
| PDZD8 | PDZ domain containing 8 | 0.0546198 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0546031 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0540938 |
| B2M | beta-2-microglobulin | 0.0523352 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0500176 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0496716 |
| SMAD3 | SMAD family member 3 | 0.0483692 |
| DST | dystonin | 0.0481645 |
| BPTF | bromodomain PHD finger transcription factor | 0.0480705 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0479316 |
| LYZ | lysozyme | 0.0477684 |
| PTMA | prothymosin, alpha | 0.0455157 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0422602 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0400839 |
| UTRN | utrophin | 0.0395404 |
| RPS8 | ribosomal protein S8 | 0.0388642 |
| CENPF | centromere protein F, 350/400kDa | 0.0388622 |
| CD2AP | CD2-associated protein | 0.0366403 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0364046 |
| MMP7 | matrix metallopeptidase 7 | 0.0362196 |
| TMC5 | transmembrane channel-like 5 | 0.035398 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0349029 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0348513 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0338028 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0336421 |
| ACTG1 | actin gamma 1 | 0.0334096 |
| RPL13A | ribosomal protein L13a | 0.0333181 |
| RAB10 | RAB10, member RAS oncogene family | 0.0328074 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0325936 |
| RPS2 | ribosomal protein S2 | 0.0324363 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0317649 |
| DNM2 | dynamin 2 | 0.0317306 |
| ETV6 | ets variant 6 | 0.0317203 |
| ITGA1 | integrin, alpha 1 | 0.031539 |
| PLK2 | polo-like kinase 2 | 0.0312699 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.030968 |
| ERBIN | erbb2 interacting protein | 0.0309581 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0307235 |
| LIMA1 | LIM domain and actin binding 1 | 0.0304299 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0303037 |
| RPS12 | ribosomal protein S12 | 0.0299946 |
| TXNIP | thioredoxin interacting protein | 0.0293722 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0291881 |
| CD44 | CD44 molecule (Indian blood group) | 0.0289008 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0287318 |
| TCF12 | transcription factor 12 | 0.0286826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0280349 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0280026 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0278652 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0275932 |
| SET | SET nuclear proto-oncogene | 0.0275823 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0271132 |
| RPS3 | ribosomal protein S3 | 0.026921 |
| RPL4 | ribosomal protein L4 | 0.0268597 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0267746 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0259435 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0258654 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0257807 |
| CLIC5 | chloride intracellular channel 5 | 0.025334 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0252632 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0251388 |
| TPX2 | TPX2, microtubule-associated | 0.0250874 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0249864 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0243938 |
| WWC1 | WW and C2 domain containing 1 | 0.0243935 |
| NF1 | neurofibromin 1 | 0.0240764 |
| PYGB | phosphorylase, glycogen; brain | 0.0238707 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0237189 |
| ITSN2 | intersectin 2 | 0.02368 |
| CUX1 | cut-like homeobox 1 | 0.023655 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.0233252 |
| SERINC5 | serine incorporator 5 | 0.0232817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232473 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0232043 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 0.0231783 |
| NXN | nucleoredoxin | 0.022906 |
| SMYD3 | SET and MYND domain containing 3 | 0.0229042 |
| RACK1 | receptor for activated C kinase 1 | 0.0224249 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0224086 |
| TRIM56 | tripartite motif containing 56 | 0.0223339 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0219042 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0218923 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0218692 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0218279 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0217713 |
| EHBP1 | EH domain binding protein 1 | 0.0216284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.147288 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.106395 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0968736 |
| EGR1 | early growth response 1 | -0.0956377 |
| EZR | ezrin | -0.0919747 |
| FRY | furry homolog (Drosophila) | -0.0766905 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0733645 |
| ANXA2 | annexin A2 | -0.0723353 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0700616 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0677741 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0639573 |
| INTS6 | integrator complex subunit 6 | -0.0634504 |
| VEGFA | vascular endothelial growth factor A | -0.0593665 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.059282 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0592621 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0563169 |
| TRIB1 | tribbles pseudokinase 1 | -0.0542284 |
| PRELID2 | PRELI domain containing 2 | -0.0530889 |
| ACTN4 | actinin, alpha 4 | -0.0523166 |
| LDHA | lactate dehydrogenase A | -0.0508936 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0503792 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0495263 |
| TUFT1 | tuftelin 1 | -0.0445795 |
| FBXO32 | F-box protein 32 | -0.0442363 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0435458 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0429417 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0428614 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0422382 |
| VCL | vinculin | -0.0399168 |
| TMSB10 | thymosin beta 10 | -0.0392482 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0388823 |
| ABHD2 | abhydrolase domain containing 2 | -0.0386099 |
| ADIPOR2 | adiponectin receptor 2 | -0.0385895 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.038382 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0383665 |
| MCL1 | myeloid cell leukemia 1 | -0.0380313 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0376139 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0352561 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0350149 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337579 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0337124 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0335643 |
| BBX | bobby sox homolog (Drosophila) | -0.0322418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0321257 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0309914 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0308399 |
| LAMA4 | laminin, alpha 4 | -0.0308346 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0305549 |
| EMP1 | epithelial membrane protein 1 | -0.0305315 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0298259 |
| RTN4 | reticulon 4 | -0.0297884 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0296641 |
| S100A10 | S100 calcium binding protein A10 | -0.0296381 |
| AGR2 | anterior gradient 2 | -0.0292772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0291994 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0289997 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0287295 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0285017 |
| ARF4 | ADP-ribosylation factor 4 | -0.0275111 |
| INSIG1 | insulin induced gene 1 | -0.0269389 |
| ATF3 | activating transcription factor 3 | -0.0269337 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0268788 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0267833 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0265094 |
| FOSL1 | FOS-like antigen 1 | -0.0262021 |
| MYADM | myeloid-associated differentiation marker | -0.0254877 |
| ANXA1 | annexin A1 | -0.0253807 |
| MORF4L2 | mortality factor 4 like 2 | -0.0252293 |
| TXNRD1 | thioredoxin reductase 1 | -0.0251708 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0251497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0244416 |
| CCNL1 | cyclin L1 | -0.0244101 |
| POTEF | POTE ankyrin domain family, member F | -0.0243197 |
| RASEF | RAS and EF-hand domain containing | -0.0241079 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0236615 |
| ATXN1 | ataxin 1 | -0.0236339 |
| EFNA5 | ephrin-A5 | -0.0233659 |
| LMNA | lamin A/C | -0.0233172 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0232827 |
| WASF2 | WAS protein family, member 2 | -0.02325 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0231987 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0229479 |
| DSTN | destrin (actin depolymerizing factor) | -0.0228625 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0226487 |
| RPL18 | ribosomal protein L18 | -0.0224051 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0223505 |
| KRT20 | keratin 20, type I | -0.0222583 |
| SDCBP | syndecan binding protein (syntenin) | -0.0221432 |
| SNX14 | sorting nexin 14 | -0.0219539 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0218905 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | -0.021819 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0216176 |
| RPL21 | ribosomal protein L21 | -0.0215882 |
| FOXO3 | forkhead box O3 | -0.0215453 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0214443 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0213087 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0210848 |
| PKM | pyruvate kinase, muscle | -0.0210784 |
| PFN1 | profilin 1 | -0.0209855 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0208583 |
