| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.484753 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.142734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127746 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0851399 |
| EHBP1 | EH domain binding protein 1 | 0.0714982 |
| DSPP | dentin sialophosphoprotein | 0.0701128 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0679132 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0575605 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0531362 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0510038 |
| FAM107B | family with sequence similarity 107, member B | 0.0472817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0451292 |
| ITGAV | integrin, alpha V | 0.0445496 |
| GPC6 | glypican 6 | 0.0423887 |
| VCL | vinculin | 0.0385884 |
| SVIL | supervillin | 0.0380635 |
| FOXP1 | forkhead box P1 | 0.0377718 |
| BCL2L1 | BCL2-like 1 | 0.0361229 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0348559 |
| FRMD5 | FERM domain containing 5 | 0.034816 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0327655 |
| GK | glycerol kinase | 0.0323876 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0322504 |
| FN1 | fibronectin 1 | 0.0316609 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0301417 |
| KYNU | kynureninase | 0.0293832 |
| ATXN1 | ataxin 1 | 0.0292279 |
| CTSB | cathepsin B | 0.0290814 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0288144 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.027541 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268269 |
| KLF6 | Kruppel-like factor 6 | 0.026454 |
| CNKSR3 | CNKSR family member 3 | 0.0264346 |
| DST | dystonin | 0.025255 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0251441 |
| RASA2 | RAS p21 protein activator 2 | 0.0245324 |
| RAI14 | retinoic acid induced 14 | 0.0244838 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0241486 |
| PTCHD4 | patched domain containing 4 | 0.0241017 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0234814 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0230801 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0230575 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0230235 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0224515 |
| APOB | apolipoprotein B | 0.0223801 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0215314 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0213323 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.021249 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0211584 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0208652 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0204993 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0203479 |
| RIGI | RNA sensor RIG-I | 0.0202841 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0202676 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0202466 |
| ZNF644 | zinc finger protein 644 | 0.019636 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0196277 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0193513 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0191339 |
| RSU1 | Ras suppressor protein 1 | 0.0186385 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0181721 |
| AFF1 | AF4/FMR2 family, member 1 | 0.018054 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0180425 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0179891 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0179342 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0176737 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0176542 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0176017 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0175125 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0174708 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0173649 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0171084 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0169983 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0169525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0168948 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0167139 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0165701 |
| GPC3 | glypican 3 | 0.0165581 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0164036 |
| PALLD | palladin, cytoskeletal associated protein | 0.0163354 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0162686 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0160952 |
| GRB10 | growth factor receptor-bound protein 10 | 0.016043 |
| RNF213 | ring finger protein 213 | 0.0158337 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0157802 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0156049 |
| IGF1R | insulin-like growth factor 1 receptor | 0.015469 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0154352 |
| ITGA1 | integrin, alpha 1 | 0.0152817 |
| AHNAK | AHNAK nucleoprotein | 0.015161 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0149881 |
| ENAH | enabled homolog (Drosophila) | 0.0147734 |
| SMAD3 | SMAD family member 3 | 0.0147506 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0147389 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0144896 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0144629 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0142237 |
| YME1L1 | YME1-like 1 ATPase | 0.0141314 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0139774 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.013885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.196259 |
| C3 | complement component 3 | -0.15547 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.11612 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.113311 |
| APOA2 | apolipoprotein A-II | -0.0926516 |
| MT2A | metallothionein 2A | -0.0721115 |
| NDRG1 | N-myc downstream regulated 1 | -0.0666521 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0642429 |
| TMSB10 | thymosin beta 10 | -0.0583262 |
| FTL | ferritin, light polypeptide | -0.0543492 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0518129 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497911 |
| RPL37A | ribosomal protein L37a | -0.0473055 |
| RPL35A | ribosomal protein L35a | -0.0463944 |
| RPL31 | ribosomal protein L31 | -0.0445853 |
| VEGFA | vascular endothelial growth factor A | -0.0426055 |
| RPS6 | ribosomal protein S6 | -0.0404013 |
| DTNA | dystrobrevin, alpha | -0.0402619 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0382766 |
| RPS19 | ribosomal protein S19 | -0.0382618 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0363765 |
| AHSG | alpha-2-HS-glycoprotein | -0.0355229 |
| APOE | apolipoprotein E | -0.0354603 |
| RPS24 | ribosomal protein S24 | -0.034811 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347746 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0339478 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0338678 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0336035 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0330985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0329896 |
| PTMA | prothymosin, alpha | -0.0322659 |
| RPL11 | ribosomal protein L11 | -0.0306293 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0305159 |
| RPL23 | ribosomal protein L23 | -0.0304776 |
| APOA1 | apolipoprotein A-I | -0.0304113 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0299737 |
| RPL5 | ribosomal protein L5 | -0.0298764 |
| RPS21 | ribosomal protein S21 | -0.0295936 |
| GNAS | GNAS complex locus | -0.0294482 |
| RPS29 | ribosomal protein S29 | -0.0288019 |
| CALR | calreticulin | -0.0276629 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0276188 |
| INSIG2 | insulin induced gene 2 | -0.0273461 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269163 |
| RPL34 | ribosomal protein L34 | -0.0267411 |
| RPS13 | ribosomal protein S13 | -0.0264621 |
| RPL9 | ribosomal protein L9 | -0.0263419 |
| PCBP2 | poly(rC) binding protein 2 | -0.0260642 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0260639 |
| PKM | pyruvate kinase, muscle | -0.0257996 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0256992 |
| CPE | carboxypeptidase E | -0.0254475 |
| GSE1 | Gse1 coiled-coil protein | -0.0253983 |
| SETD5 | SET domain containing 5 | -0.0249611 |
| RPS27A | ribosomal protein S27a | -0.0247814 |
| IL32 | interleukin 32 | -0.0246433 |
| HMGA1 | high mobility group AT-hook 1 | -0.024434 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0242795 |
| RPS8 | ribosomal protein S8 | -0.0241118 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0238821 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0237229 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0236218 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0235186 |
| RPS14 | ribosomal protein S14 | -0.023122 |
| RPS11 | ribosomal protein S11 | -0.0226429 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0224399 |
| RPL7A | ribosomal protein L7a | -0.0223667 |
| LYZ | lysozyme | -0.0222476 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0219128 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0218851 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0215157 |
| HLA-A | major histocompatibility complex, class I, A | -0.0214666 |
| ZNF292 | zinc finger protein 292 | -0.0212325 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0210856 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0209284 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.020512 |
| TMEM51 | transmembrane protein 51 | -0.0203346 |
| RBM39 | RNA binding motif protein 39 | -0.020077 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0200387 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0199135 |
| WDR45B | WD repeat domain 45B | -0.0197768 |
| RPS10 | ribosomal protein S10 | -0.0196796 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0196752 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0195401 |
| RPS3 | ribosomal protein S3 | -0.0195062 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0192411 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0188952 |
| GOLGA4 | golgin A4 | -0.0183872 |
| RPL30 | ribosomal protein L30 | -0.0183213 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0182638 |
| SDC4 | syndecan 4 | -0.018221 |
| VIM | vimentin | -0.01817 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0180168 |
| PRELID2 | PRELI domain containing 2 | -0.0178704 |
| RPL19 | ribosomal protein L19 | -0.0178017 |
| RPS23 | ribosomal protein S23 | -0.01773 |
| PFN1 | profilin 1 | -0.0176637 |
| RPS25 | ribosomal protein S25 | -0.0175335 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0174769 |
| PDE8A | phosphodiesterase 8A | -0.0171179 |
