| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.147675 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.105108 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.104842 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0973644 |
| LMO7 | LIM domain 7 | 0.0831807 |
| TMC5 | transmembrane channel-like 5 | 0.0778821 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0727591 |
| DSPP | dentin sialophosphoprotein | 0.0713433 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.069234 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0675102 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.057767 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0544002 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0510108 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0480979 |
| RPS6 | ribosomal protein S6 | 0.0478483 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.047805 |
| FTL | ferritin, light polypeptide | 0.0471992 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0446344 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0445838 |
| RPS2 | ribosomal protein S2 | 0.0433985 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0427788 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0422801 |
| SNX9 | sorting nexin 9 | 0.0411751 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0409738 |
| MYOF | myoferlin | 0.0390746 |
| BPTF | bromodomain PHD finger transcription factor | 0.038869 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0372805 |
| SQSTM1 | sequestosome 1 | 0.037165 |
| ANXA2 | annexin A2 | 0.0367148 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0366237 |
| ANXA1 | annexin A1 | 0.0360313 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0354835 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0345002 |
| KLHL24 | kelch-like family member 24 | 0.0337671 |
| HLA-E | major histocompatibility complex, class I, E | 0.0331384 |
| TRAM1 | translocation associated membrane protein 1 | 0.0317917 |
| RPS25 | ribosomal protein S25 | 0.0311833 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.0304103 |
| UBC | ubiquitin C | 0.0302702 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.030167 |
| TMF1 | TATA element modulatory factor 1 | 0.030044 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0297116 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0294272 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.02934 |
| RPS8 | ribosomal protein S8 | 0.0292898 |
| TXNIP | thioredoxin interacting protein | 0.029205 |
| DSG2 | desmoglein 2 | 0.0291694 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0289655 |
| MED13 | mediator complex subunit 13 | 0.0277708 |
| TXNRD1 | thioredoxin reductase 1 | 0.0275802 |
| RPL4 | ribosomal protein L4 | 0.0275035 |
| HKDC1 | hexokinase domain containing 1 | 0.0264953 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0263877 |
| AHNAK | AHNAK nucleoprotein | 0.0253924 |
| RPL39 | ribosomal protein L39 | 0.0250668 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0248839 |
| RPL7 | ribosomal protein L7 | 0.024789 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0245493 |
| DST | dystonin | 0.0244322 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0243726 |
| LIPH | lipase, member H | 0.0243566 |
| GOLGA4 | golgin A4 | 0.024041 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0240017 |
| MKI67 | marker of proliferation Ki-67 | 0.0237835 |
| CLTC | clathrin, heavy chain (Hc) | 0.0235966 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0234558 |
| UBE4A | ubiquitination factor E4A | 0.0233683 |
| SLK | STE20-like kinase | 0.023263 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0231727 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0231592 |
| FNIP1 | folliculin interacting protein 1 | 0.0230607 |
| CANX | calnexin | 0.0230352 |
| SLMAP | sarcolemma associated protein | 0.0230272 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226248 |
| ATF4 | activating transcription factor 4 | 0.0225902 |
| RTN3 | reticulon 3 | 0.0224927 |
| RAB10 | RAB10, member RAS oncogene family | 0.0223925 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0221997 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0218803 |
| SET | SET nuclear proto-oncogene | 0.0217686 |
| SFTPA2 | surfactant protein A2 | 0.0214713 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.021407 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213893 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0212281 |
| MYO6 | myosin VI | 0.0212083 |
| OCLN | occludin | 0.021153 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0210224 |
| GPATCH8 | G patch domain containing 8 | 0.0210125 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0206858 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0206487 |
| RESF1 | retroelement silencing factor 1 | 0.0206482 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0205345 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0203796 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0202604 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0201781 |
| EPCAM | epithelial cell adhesion molecule | 0.0200756 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0200582 |
| KIF5B | kinesin family member 5B | 0.0198972 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0196832 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0193989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.263526 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.240445 |
| TMSB10 | thymosin beta 10 | -0.175692 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.171336 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.110201 |
| FLNB | filamin B, beta | -0.073842 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0730075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0647419 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0615393 |
| TNIK | TRAF2 and NCK interacting kinase | -0.05903 |
| RPS19 | ribosomal protein S19 | -0.0561991 |
| VEGFA | vascular endothelial growth factor A | -0.0561214 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0527497 |
| KRT8 | keratin 8, type II | -0.0517453 |
| ITGB4 | integrin, beta 4 | -0.0509556 |
| COBL | cordon-bleu WH2 repeat protein | -0.0484828 |
| EZR | ezrin | -0.0479264 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0467537 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0467338 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0460044 |
| ATXN1 | ataxin 1 | -0.0459915 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0458525 |
| NDRG1 | N-myc downstream regulated 1 | -0.0454067 |
| FAT1 | FAT atypical cadherin 1 | -0.0446868 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0431158 |
| MECOM | MDS1 and EVI1 complex locus | -0.0431064 |
| RAD51B | RAD51 paralog B | -0.0427858 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0424355 |
| INSIG1 | insulin induced gene 1 | -0.041881 |
| POTEF | POTE ankyrin domain family, member F | -0.0411615 |
| PFN1 | profilin 1 | -0.0408001 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0402792 |
| KLHL29 | kelch-like family member 29 | -0.040175 |
| AUTS2 | autism susceptibility candidate 2 | -0.0395179 |
| ACTN4 | actinin, alpha 4 | -0.0394527 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0393631 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0385834 |
| EHBP1 | EH domain binding protein 1 | -0.03831 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0382734 |
| S100A10 | S100 calcium binding protein A10 | -0.0380684 |
| CDK6 | cyclin-dependent kinase 6 | -0.0376973 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0374286 |
| PRKCA | protein kinase C, alpha | -0.0373529 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0371329 |
| LMNA | lamin A/C | -0.036763 |
| FASN | fatty acid synthase | -0.0356173 |
| PKM | pyruvate kinase, muscle | -0.0352998 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0352368 |
| S100A11 | S100 calcium binding protein A11 | -0.0342989 |
| CLDN4 | claudin 4 | -0.0341711 |
| MSI2 | musashi RNA-binding protein 2 | -0.0340417 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0331345 |
| INTS6 | integrator complex subunit 6 | -0.032415 |
| RPL35A | ribosomal protein L35a | -0.0322304 |
| LAMA5 | laminin, alpha 5 | -0.032057 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313223 |
| EXOC4 | exocyst complex component 4 | -0.0311053 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0309478 |
| KRT7 | keratin 7, type II | -0.0302519 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0299498 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.0296092 |
| TTYH3 | tweety family member 3 | -0.0296075 |
| DENND1A | DENN/MADD domain containing 1A | -0.0294575 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.029379 |
| CMIP | c-Maf inducing protein | -0.0291958 |
| EGR1 | early growth response 1 | -0.0291836 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0285668 |
| PRDM16 | PR domain containing 16 | -0.0283772 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0282621 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0279984 |
| PRELID2 | PRELI domain containing 2 | -0.027723 |
| PCBP2 | poly(rC) binding protein 2 | -0.0271876 |
| ETNK1 | ethanolamine kinase 1 | -0.0270445 |
| MUC1 | mucin 1, cell surface associated | -0.0269901 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0267862 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0267506 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0266291 |
| S100A6 | S100 calcium binding protein A6 | -0.0266043 |
| CNKSR3 | CNKSR family member 3 | -0.0262548 |
| CCNL1 | cyclin L1 | -0.0262368 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0261767 |
| KRT18 | keratin 18, type I | -0.0261166 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0260418 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0260201 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0260021 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.025885 |
| CLDN7 | claudin 7 | -0.025394 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0253277 |
| NFIA | nuclear factor I/A | -0.0247676 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0247498 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0246285 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0244363 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243894 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0240928 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0238522 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0238282 |
| TFRC | transferrin receptor | -0.0237343 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0236855 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0235709 |
| SEC61G | Sec61 gamma subunit | -0.0234473 |
