| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.220607 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.145422 |
| EXT1 | exostosin glycosyltransferase 1 | 0.141038 |
| HDAC9 | histone deacetylase 9 | 0.139269 |
| DTNA | dystrobrevin, alpha | 0.10245 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0997622 |
| RPS6 | ribosomal protein S6 | 0.0953867 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0884855 |
| RPS12 | ribosomal protein S12 | 0.0884662 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0773311 |
| CD44 | CD44 molecule (Indian blood group) | 0.0751741 |
| RPS2 | ribosomal protein S2 | 0.0741961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0694517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0679718 |
| RPS3 | ribosomal protein S3 | 0.0650683 |
| JMJD1C | jumonji domain containing 1C | 0.0589804 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0564191 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0550507 |
| NAV3 | neuron navigator 3 | 0.0547359 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0525427 |
| USP34 | ubiquitin specific peptidase 34 | 0.05234 |
| RACK1 | receptor for activated C kinase 1 | 0.0518796 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0507376 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0505069 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0497359 |
| SLC38A2 | solute carrier family 38, member 2 | 0.049684 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0481109 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0470246 |
| MYO10 | myosin X | 0.0464165 |
| RUNX1 | runt-related transcription factor 1 | 0.0458814 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0451814 |
| RPL7 | ribosomal protein L7 | 0.0439698 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0408132 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.040437 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0401674 |
| KYNU | kynureninase | 0.0388433 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0388075 |
| RPS8 | ribosomal protein S8 | 0.0379644 |
| ANKRD28 | ankyrin repeat domain 28 | 0.037692 |
| GPHN | gephyrin | 0.037324 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0365965 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0363512 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0357018 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0352762 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0348279 |
| RPS17 | ribosomal protein S17 | 0.034021 |
| EFNA5 | ephrin-A5 | 0.0333582 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0331523 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0328421 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0320531 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0319085 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0318775 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0318211 |
| RPL4 | ribosomal protein L4 | 0.0313088 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0306677 |
| RND3 | Rho family GTPase 3 | 0.0302363 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0296493 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0292196 |
| RPL37A | ribosomal protein L37a | 0.028899 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0285143 |
| TXNIP | thioredoxin interacting protein | 0.0281574 |
| SATB2 | SATB homeobox 2 | 0.0268402 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.026799 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0266699 |
| SET | SET nuclear proto-oncogene | 0.0264714 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0263588 |
| RASAL2 | RAS protein activator like 2 | 0.0260061 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0251617 |
| BPTF | bromodomain PHD finger transcription factor | 0.0250983 |
| HMGA2 | high mobility group AT-hook 2 | 0.0250421 |
| AHNAK | AHNAK nucleoprotein | 0.0246607 |
| EFNB2 | ephrin-B2 | 0.0245208 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.024436 |
| EMP1 | epithelial membrane protein 1 | 0.0244122 |
| CDK6 | cyclin-dependent kinase 6 | 0.0233456 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0232187 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0231358 |
| ENO1 | enolase 1, (alpha) | 0.0229701 |
| LIMA1 | LIM domain and actin binding 1 | 0.0229655 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0228773 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0228582 |
| RPL12 | ribosomal protein L12 | 0.0228421 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0227243 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0227126 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0224743 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0223706 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0223315 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0222419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0222312 |
| ZNF638 | zinc finger protein 638 | 0.0222143 |
| TLE4 | transducin-like enhancer of split 4 | 0.0221323 |
| EXOC6B | exocyst complex component 6B | 0.0218384 |
| DST | dystonin | 0.02182 |
| MED13L | mediator complex subunit 13-like | 0.0217155 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0216048 |
| INTS6 | integrator complex subunit 6 | 0.0214961 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214832 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0213934 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0212195 |
| FOXP1 | forkhead box P1 | 0.0211715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.234498 |
| TMSB10 | thymosin beta 10 | -0.204722 |
| PTMA | prothymosin, alpha | -0.185239 |
| MMP12 | matrix metallopeptidase 12 | -0.13472 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.124825 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0949301 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0808018 |
| MT2A | metallothionein 2A | -0.0787808 |
| VIM | vimentin | -0.0767188 |
| TPM4 | tropomyosin 4 | -0.0739476 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0725229 |
| RPLP1 | ribosomal protein, large, P1 | -0.0689715 |
| CDH13 | cadherin 13 | -0.0677567 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0630749 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0616664 |
| FN1 | fibronectin 1 | -0.0604235 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0551826 |
| PKM | pyruvate kinase, muscle | -0.0520565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0504515 |
| LSAMP | limbic system-associated membrane protein | -0.0495981 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0494141 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0486311 |
| POTEF | POTE ankyrin domain family, member F | -0.0475707 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0473435 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0469911 |
| NTM | neurotrimin | -0.0466191 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0462644 |
| YBX1 | Y box binding protein 1 | -0.0450399 |
| KIAA1549L | KIAA1549-like | -0.0435489 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0435055 |
| CANX | calnexin | -0.043179 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0412742 |
| RPL35A | ribosomal protein L35a | -0.0409579 |
| CALR | calreticulin | -0.0400557 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0395773 |
| ANXA2 | annexin A2 | -0.0389711 |
| ZNF292 | zinc finger protein 292 | -0.0383257 |
| FTL | ferritin, light polypeptide | -0.0379152 |
| CAVIN1 | caveolae associated protein 1 | -0.0370652 |
| NDRG1 | N-myc downstream regulated 1 | -0.0367782 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.03635 |
| PGK1 | phosphoglycerate kinase 1 | -0.0363061 |
| PFN1 | profilin 1 | -0.0361846 |
| CENPF | centromere protein F, 350/400kDa | -0.0358267 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0356929 |
| VCL | vinculin | -0.0354598 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0341657 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0339436 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0337962 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0336845 |
| NRP2 | neuropilin 2 | -0.0334268 |
| DIAPH3 | diaphanous-related formin 3 | -0.0319222 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0315069 |
| RPS21 | ribosomal protein S21 | -0.0311901 |
| RBM39 | RNA binding motif protein 39 | -0.0310959 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0310709 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0310105 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.030445 |
| RTN4 | reticulon 4 | -0.0304011 |
| SEPTIN7 | septin 7 | -0.0302513 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0299873 |
| TPI1 | triosephosphate isomerase 1 | -0.0297455 |
| EGR1 | early growth response 1 | -0.0297455 |
| QKI | QKI, KH domain containing, RNA binding | -0.0295563 |
| H1-0 | H1.0 linker histone | -0.0295377 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0295003 |
| TMEM263 | transmembrane protein 263 | -0.0294383 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0293494 |
| ASPH | aspartate beta-hydroxylase | -0.0292979 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028707 |
| FAM162A | family with sequence similarity 162, member A | -0.02862 |
| BNC2 | basonuclin 2 | -0.0285745 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0280349 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0277745 |
| HDLBP | high density lipoprotein binding protein | -0.0277532 |
| MT1X | metallothionein 1X | -0.0275978 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275935 |
| HMGA1 | high mobility group AT-hook 1 | -0.027585 |
| CCDC80 | coiled-coil domain containing 80 | -0.0275332 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0274038 |
| RPL13A | ribosomal protein L13a | -0.0273309 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0272876 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0272033 |
| LMNA | lamin A/C | -0.02708 |
| GNAS | GNAS complex locus | -0.0266656 |
| DNER | delta/notch-like EGF repeat containing | -0.0266183 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.026522 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.026317 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0261567 |
| NLGN1 | neuroligin 1 | -0.0260474 |
| RPS24 | ribosomal protein S24 | -0.0257903 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0257434 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0256736 |
| RPS19 | ribosomal protein S19 | -0.0253482 |
| DEK | DEK proto-oncogene | -0.0251658 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0249441 |
| SETD5 | SET domain containing 5 | -0.0249101 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0245543 |
| ANLN | anillin, actin binding protein | -0.024121 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0239281 |
