| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.146882 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.133864 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.123035 |
| MUC16 | mucin 16, cell surface associated | 0.114746 |
| MYO1E | myosin IE | 0.10969 |
| TJP1 | tight junction protein 1 | 0.0934731 |
| KRT17 | keratin 17, type I | 0.0933539 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0932405 |
| NDRG1 | N-myc downstream regulated 1 | 0.0918524 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0878205 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0805153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0789922 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0783767 |
| MT2A | metallothionein 2A | 0.0779683 |
| IGF1R | insulin-like growth factor 1 receptor | 0.076073 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0736553 |
| IGF2 | insulin-like growth factor 2 | 0.0713969 |
| MXD1 | MAX dimerization protein 1 | 0.0699769 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0696281 |
| EZR | ezrin | 0.0687184 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0673909 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0668487 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0668207 |
| MYOF | myoferlin | 0.0667535 |
| SVIL | supervillin | 0.0650341 |
| B2M | beta-2-microglobulin | 0.0620185 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0596621 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0583345 |
| RPL37A | ribosomal protein L37a | 0.0560976 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0558685 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0549837 |
| UBC | ubiquitin C | 0.0530246 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0530002 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0525853 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0524776 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0518803 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0518796 |
| KYNU | kynureninase | 0.0511558 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.051 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.050984 |
| VMP1 | vacuole membrane protein 1 | 0.0505197 |
| FMNL2 | formin-like 2 | 0.0503422 |
| ABHD17C | abhydrolase domain containing 17C | 0.0496167 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.049576 |
| DIAPH1 | diaphanous-related formin 1 | 0.0495433 |
| DTNA | dystrobrevin, alpha | 0.0490017 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0478261 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0471506 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0470553 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0460874 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0456114 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0452996 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0450779 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0442508 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0441744 |
| DENND2C | DENN/MADD domain containing 2C | 0.0440883 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0438112 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.043114 |
| ZNF292 | zinc finger protein 292 | 0.0426985 |
| PARD3 | par-3 family cell polarity regulator | 0.0417778 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0411599 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0408114 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0401329 |
| IFI44 | interferon-induced protein 44 | 0.0401286 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0400059 |
| USP34 | ubiquitin specific peptidase 34 | 0.0398348 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.039732 |
| RACK1 | receptor for activated C kinase 1 | 0.0395997 |
| TMSB10 | thymosin beta 10 | 0.0394664 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393659 |
| EFNA5 | ephrin-A5 | 0.0382517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0380544 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0379142 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0375028 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0374642 |
| ZNF638 | zinc finger protein 638 | 0.0373643 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0370022 |
| FA2H | fatty acid 2-hydroxylase | 0.0366552 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0363424 |
| RPS20 | ribosomal protein S20 | 0.0360521 |
| SQSTM1 | sequestosome 1 | 0.035116 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0349178 |
| RPS24 | ribosomal protein S24 | 0.0346835 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0345628 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0345277 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0344267 |
| RBM15 | RNA binding motif protein 15 | 0.0343766 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0342475 |
| CNKSR3 | CNKSR family member 3 | 0.0341849 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0340767 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.034051 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0339217 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.033748 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0336224 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0331318 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0331249 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0330222 |
| ZNF207 | zinc finger protein 207 | 0.0325947 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0325577 |
| DENND1A | DENN/MADD domain containing 1A | 0.0322488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | -0.213418 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.100227 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0837107 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0812873 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0733161 |
| EGFR | epidermal growth factor receptor | -0.0712063 |
| INHBA | inhibin, beta A | -0.0693029 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.068665 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0662361 |
| RUNX1 | runt-related transcription factor 1 | -0.0657078 |
| CALD1 | caldesmon 1 | -0.0653421 |
| GPC6 | glypican 6 | -0.0638574 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0630595 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0614485 |
| CD44 | CD44 molecule (Indian blood group) | -0.0610651 |
| VIM | vimentin | -0.0573491 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0558888 |
| ANXA1 | annexin A1 | -0.0538961 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0538561 |
| VCL | vinculin | -0.0530578 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0512864 |
| RFX7 | regulatory factor X, 7 | -0.050095 |
| ARCN1 | archain 1 | -0.0497771 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0497069 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0496864 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0492349 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0490941 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0482215 |
| MEIS1 | Meis homeobox 1 | -0.0479075 |
| CLTC | clathrin, heavy chain (Hc) | -0.0478876 |
| OSMR | oncostatin M receptor | -0.0470985 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0460493 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0457407 |
| POTEF | POTE ankyrin domain family, member F | -0.0454141 |
| CADM2 | cell adhesion molecule 2 | -0.0452877 |
| MYO1B | myosin IB | -0.0446174 |
| ETNK1 | ethanolamine kinase 1 | -0.0438363 |
| RTN4 | reticulon 4 | -0.0435661 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0428731 |
| LAMB1 | laminin, beta 1 | -0.0427481 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0422506 |
| PKM | pyruvate kinase, muscle | -0.0422398 |
| SRP54 | signal recognition particle 54kDa | -0.0418509 |
| PDS5B | PDS5 cohesin associated factor B | -0.0416931 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0413649 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0413424 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0409959 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0407146 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0407027 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | -0.0404291 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0402669 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0400934 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0400799 |
| MORF4L2 | mortality factor 4 like 2 | -0.0399823 |
| RANBP2 | RAN binding protein 2 | -0.0399633 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0399394 |
| FRMD5 | FERM domain containing 5 | -0.0391068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0388933 |
| DENND5B | DENN/MADD domain containing 5B | -0.0386027 |
| RRBP1 | ribosome binding protein 1 | -0.0385226 |
| CCDC6 | coiled-coil domain containing 6 | -0.0384052 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0379484 |
| COPA | coatomer protein complex, subunit alpha | -0.0379215 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0379129 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0374905 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0372648 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0372574 |
| CALR | calreticulin | -0.0369027 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0368547 |
| TPM4 | tropomyosin 4 | -0.0367917 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0367101 |
| MSI2 | musashi RNA-binding protein 2 | -0.0366738 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0356537 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0349329 |
| ATXN10 | ataxin 10 | -0.0348122 |
| SRPK2 | SRSF protein kinase 2 | -0.0344353 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0343263 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0341431 |
| FAM204A | family with sequence similarity 204, member A | -0.0340874 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0339617 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0339092 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0338195 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0335345 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0332791 |
| SP100 | SP100 nuclear antigen | -0.033265 |
| EHBP1 | EH domain binding protein 1 | -0.0332274 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0328279 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0327773 |
| PRELID2 | PRELI domain containing 2 | -0.0327535 |
| HBS1L | HBS1-like translational GTPase | -0.0326816 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.032489 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0324631 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0324464 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0323233 |
| NHSL1 | NHS-like 1 | -0.0319127 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0317646 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.03167 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0312834 |
| FTL | ferritin, light polypeptide | -0.0312723 |
| TES | testin LIM domain protein | -0.0311669 |
