| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.193856 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.161864 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.156426 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.149525 |
| LAMB3 | laminin, beta 3 | 0.116467 |
| RPS3 | ribosomal protein S3 | 0.098055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0901297 |
| TXNIP | thioredoxin interacting protein | 0.0806836 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0776016 |
| RACK1 | receptor for activated C kinase 1 | 0.0759248 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0700477 |
| RPS12 | ribosomal protein S12 | 0.0677301 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0675753 |
| RPL18 | ribosomal protein L18 | 0.0672549 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0661587 |
| B2M | beta-2-microglobulin | 0.06235 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0610463 |
| KRT19 | keratin 19, type I | 0.0594867 |
| RPL32 | ribosomal protein L32 | 0.0571283 |
| RPL12 | ribosomal protein L12 | 0.0533377 |
| KLF6 | Kruppel-like factor 6 | 0.0531415 |
| SQSTM1 | sequestosome 1 | 0.0528 |
| RPL26 | ribosomal protein L26 | 0.0523749 |
| DSG2 | desmoglein 2 | 0.0510216 |
| DSPP | dentin sialophosphoprotein | 0.0483724 |
| ARRDC3 | arrestin domain containing 3 | 0.0479793 |
| ACTG1 | actin gamma 1 | 0.0473127 |
| AHNAK | AHNAK nucleoprotein | 0.046698 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0463548 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0462403 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0448762 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0436732 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410351 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0399907 |
| SVIL | supervillin | 0.0398535 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0395445 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0394891 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0394841 |
| ANXA2 | annexin A2 | 0.0390418 |
| IRS2 | insulin receptor substrate 2 | 0.0389114 |
| LDHA | lactate dehydrogenase A | 0.0376207 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0373362 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0372779 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0371057 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.036659 |
| SON | SON DNA binding protein | 0.0363188 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0360522 |
| DST | dystonin | 0.0358834 |
| RPL36 | ribosomal protein L36 | 0.0357877 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0357652 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0352709 |
| RPL8 | ribosomal protein L8 | 0.0352682 |
| MKI67 | marker of proliferation Ki-67 | 0.0343306 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0338272 |
| JMJD1C | jumonji domain containing 1C | 0.0337197 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0337123 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0332552 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0326271 |
| SET | SET nuclear proto-oncogene | 0.0326099 |
| WWC1 | WW and C2 domain containing 1 | 0.0322022 |
| RPS2 | ribosomal protein S2 | 0.0319917 |
| FOXP1 | forkhead box P1 | 0.0307895 |
| PGK1 | phosphoglycerate kinase 1 | 0.0307698 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0303067 |
| SMAD3 | SMAD family member 3 | 0.0297257 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0295752 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0294529 |
| EHF | ets homologous factor | 0.0294042 |
| PRELID2 | PRELI domain containing 2 | 0.0293198 |
| EPCAM | epithelial cell adhesion molecule | 0.028923 |
| ZNF292 | zinc finger protein 292 | 0.0285198 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0282398 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.028226 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0277796 |
| CDCP1 | CUB domain containing protein 1 | 0.0275626 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0275474 |
| LAMC2 | laminin, gamma 2 | 0.0269884 |
| IL6ST | interleukin 6 signal transducer | 0.0268132 |
| RPL23A | ribosomal protein L23a | 0.0267486 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0264349 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0263577 |
| ATF3 | activating transcription factor 3 | 0.0260654 |
| RNF213 | ring finger protein 213 | 0.0258758 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0256204 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0255738 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0255572 |
| RPL7 | ribosomal protein L7 | 0.025381 |
| SNX9 | sorting nexin 9 | 0.0253141 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0252989 |
| TMEM123 | transmembrane protein 123 | 0.0252702 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0251239 |
| ITGA6 | integrin, alpha 6 | 0.0245682 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0244146 |
| MX1 | MX dynamin-like GTPase 1 | 0.0243137 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0243004 |
| ENO1 | enolase 1, (alpha) | 0.0242809 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0241677 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0241109 |
| EMP1 | epithelial membrane protein 1 | 0.0241048 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0239966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.284948 |
| FTL | ferritin, light polypeptide | -0.121125 |
| RPL35A | ribosomal protein L35a | -0.101231 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0975947 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0902399 |
| RPL31 | ribosomal protein L31 | -0.0789865 |
| MUC4 | mucin 4, cell surface associated | -0.0752117 |
| VEGFA | vascular endothelial growth factor A | -0.0741379 |
| TPM4 | tropomyosin 4 | -0.0721492 |
| TMSB10 | thymosin beta 10 | -0.0656359 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0565378 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0525204 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0506594 |
| HLA-A | major histocompatibility complex, class I, A | -0.0487059 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0478217 |
| FN1 | fibronectin 1 | -0.0473595 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0455325 |
| SULF2 | sulfatase 2 | -0.0446231 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0437399 |
| RCOR1 | REST corepressor 1 | -0.0435892 |
| INTS6 | integrator complex subunit 6 | -0.0426642 |
| HLA-B | major histocompatibility complex, class I, B | -0.0407703 |
| RPS13 | ribosomal protein S13 | -0.0398906 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0383421 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0379163 |
| VCL | vinculin | -0.037487 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0370445 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0361565 |
| HLA-C | major histocompatibility complex, class I, C | -0.0358261 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0346572 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0341875 |
| CALR | calreticulin | -0.0338376 |
| C3 | complement component 3 | -0.0336498 |
| ABHD3 | abhydrolase domain containing 3 | -0.0333302 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0331 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0322125 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320548 |
| ASPH | aspartate beta-hydroxylase | -0.0316232 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0313671 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0310126 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0298077 |
| RPS24 | ribosomal protein S24 | -0.0296717 |
| POTEF | POTE ankyrin domain family, member F | -0.0295107 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0289316 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0288185 |
| RPL38 | ribosomal protein L38 | -0.0286451 |
| RPL7A | ribosomal protein L7a | -0.0283321 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0271205 |
| JUP | junction plakoglobin | -0.0268534 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0264942 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0263307 |
| NUMB | numb homolog (Drosophila) | -0.0262703 |
| RPS20 | ribosomal protein S20 | -0.0262655 |
| EGR1 | early growth response 1 | -0.0262189 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0261445 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0260445 |
| ACTN4 | actinin, alpha 4 | -0.0256796 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0256696 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025665 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0256252 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0256126 |
| RPS10 | ribosomal protein S10 | -0.0255096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0254095 |
| GNAS | GNAS complex locus | -0.0251823 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0250312 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0245028 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0244165 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0243132 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0242421 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0241427 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0238743 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0238479 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.023828 |
| NDRG1 | N-myc downstream regulated 1 | -0.0235937 |
| DAPK1 | death-associated protein kinase 1 | -0.0235685 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0235352 |
| ZNF451 | zinc finger protein 451 | -0.0233402 |
| FBXO11 | F-box protein 11 | -0.0231086 |
| HMGB1 | high mobility group box 1 | -0.0227657 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0227297 |
| DNM2 | dynamin 2 | -0.0225635 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0225436 |
| HDGF | hepatoma-derived growth factor | -0.0223799 |
| SYT14 | synaptotagmin XIV | -0.0222573 |
| TAPBP | TAP binding protein (tapasin) | -0.0222252 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.022029 |
| MCU | mitochondrial calcium uniporter | -0.021936 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0218754 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0218595 |
| USP53 | ubiquitin specific peptidase 53 | -0.0217854 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.021745 |
| YBX1 | Y box binding protein 1 | -0.0215881 |
| CTSD | cathepsin D | -0.0214643 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0209842 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0209823 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0208979 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205723 |
| RPLP1 | ribosomal protein, large, P1 | -0.0204297 |
| CUL3 | cullin 3 | -0.0202114 |
| FOSL1 | FOS-like antigen 1 | -0.0201861 |
