| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD6 | FERM domain containing 6 | 0.215826 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.164423 |
| HDAC9 | histone deacetylase 9 | 0.162328 |
| JMJD1C | jumonji domain containing 1C | 0.125762 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.124695 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.117994 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.115863 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.110422 |
| ACTG1 | actin gamma 1 | 0.103648 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.103068 |
| SGMS2 | sphingomyelin synthase 2 | 0.0995391 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0866737 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0836175 |
| RPS8 | ribosomal protein S8 | 0.0681527 |
| RPS6 | ribosomal protein S6 | 0.066045 |
| RPL12 | ribosomal protein L12 | 0.0648005 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0637437 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0552328 |
| ENO1 | enolase 1, (alpha) | 0.0550865 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0545902 |
| RPL7 | ribosomal protein L7 | 0.0541472 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0529199 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0506034 |
| RPS2 | ribosomal protein S2 | 0.0503505 |
| RPS12 | ribosomal protein S12 | 0.0492279 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0439328 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428848 |
| RACK1 | receptor for activated C kinase 1 | 0.0427504 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0425132 |
| RCOR1 | REST corepressor 1 | 0.0422091 |
| RPL8 | ribosomal protein L8 | 0.0414605 |
| EFNB2 | ephrin-B2 | 0.041278 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0412457 |
| RPL7A | ribosomal protein L7a | 0.040728 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0406294 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0405753 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0404845 |
| RPS17 | ribosomal protein S17 | 0.0401804 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0397889 |
| FNIP1 | folliculin interacting protein 1 | 0.0397116 |
| NAV3 | neuron navigator 3 | 0.0393174 |
| POTEF | POTE ankyrin domain family, member F | 0.0391673 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.039057 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0382191 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0376498 |
| BPTF | bromodomain PHD finger transcription factor | 0.0371101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0363695 |
| RPS3 | ribosomal protein S3 | 0.0360117 |
| CORO1C | coronin, actin binding protein, 1C | 0.0359899 |
| SQSTM1 | sequestosome 1 | 0.035564 |
| RUNX1 | runt-related transcription factor 1 | 0.0351777 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0350272 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0345201 |
| JUN | jun proto-oncogene | 0.0343702 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0336979 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0332787 |
| VMP1 | vacuole membrane protein 1 | 0.0308465 |
| RPS4X | ribosomal protein S4, X-linked | 0.0308252 |
| RPS5 | ribosomal protein S5 | 0.0299282 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0295933 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0295845 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295253 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0294647 |
| B2M | beta-2-microglobulin | 0.0289393 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0282864 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0275918 |
| KLF10 | Kruppel-like factor 10 | 0.027207 |
| MCL1 | myeloid cell leukemia 1 | 0.0270568 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0269648 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0269032 |
| RPL10A | ribosomal protein L10a | 0.0267873 |
| RPL23 | ribosomal protein L23 | 0.026344 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0262464 |
| RPL37 | ribosomal protein L37 | 0.0262412 |
| FBXO11 | F-box protein 11 | 0.0262233 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.026145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0257581 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0255155 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0252098 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0251158 |
| CALU | calumenin | 0.0248862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0248295 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0247688 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0247571 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0245619 |
| EMP1 | epithelial membrane protein 1 | 0.0243193 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0242508 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0241144 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.023914 |
| SET | SET nuclear proto-oncogene | 0.0238404 |
| HMGA2 | high mobility group AT-hook 2 | 0.0232557 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0231987 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0231822 |
| CUTC | cutC copper transporter | 0.0230159 |
| TRAM1 | translocation associated membrane protein 1 | 0.0229939 |
| STC1 | stanniocalcin 1 | 0.0225624 |
| UBC | ubiquitin C | 0.0223918 |
| EGFR | epidermal growth factor receptor | 0.0223268 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0222494 |
| AHNAK | AHNAK nucleoprotein | 0.0222195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0669027 |
| PTK2 | protein tyrosine kinase 2 | -0.060523 |
| ZNF292 | zinc finger protein 292 | -0.047 |
| USP3 | ubiquitin specific peptidase 3 | -0.03886 |
| LAMB3 | laminin, beta 3 | -0.0380962 |
| TTR | transthyretin | -0.0380173 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.036146 |
| RBM25 | RNA binding motif protein 25 | -0.0328377 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0328234 |
| SRPK2 | SRSF protein kinase 2 | -0.0320158 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0319381 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0318869 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0306144 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0303102 |
| FMNL2 | formin-like 2 | -0.0292074 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0290278 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0277067 |
| TCF12 | transcription factor 12 | -0.0272142 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0267029 |
| OGA | O-GlcNAcase | -0.026124 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0259967 |
| RAD51B | RAD51 paralog B | -0.0253985 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0253526 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0253328 |
| TEX10 | testis expressed 10 | -0.025311 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0252169 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0252114 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0248287 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0247521 |
| BBX | bobby sox homolog (Drosophila) | -0.0247493 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0245772 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0242741 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0242273 |
| GOLGA4 | golgin A4 | -0.0242231 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0240905 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0240734 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0239418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0236978 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0236629 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0232263 |
| NEMF | nuclear export mediator factor | -0.0231826 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0227857 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0226583 |
| FOXO3 | forkhead box O3 | -0.0225782 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0224687 |
| NF1 | neurofibromin 1 | -0.0222767 |
| RAB3IP | RAB3A interacting protein | -0.0222166 |
| RNF145 | ring finger protein 145 | -0.0221537 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0221286 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0219361 |
| WDR45B | WD repeat domain 45B | -0.0215712 |
| OLA1 | Obg-like ATPase 1 | -0.0215389 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.021525 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0212626 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0210914 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0209805 |
| MTAP | methylthioadenosine phosphorylase | -0.0209319 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0208112 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0207978 |
| POU2F1 | POU class 2 homeobox 1 | -0.0207607 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0206259 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0205923 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0202815 |
| DIAPH3 | diaphanous-related formin 3 | -0.0202799 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0202161 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0199438 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.019721 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0195988 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0195509 |
| NUP58 | nucleoporin 58 | -0.0194803 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0194105 |
| WAC | WW domain containing adaptor with coiled-coil | -0.019337 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0192327 |
| RBM39 | RNA binding motif protein 39 | -0.0191577 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0190251 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0188109 |
| FHIT | fragile histidine triad | -0.0187947 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0185927 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0184732 |
| RBM26 | RNA binding motif protein 26 | -0.0184131 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.018226 |
| TSNARE1 | t-SNARE domain containing 1 | -0.0181844 |
| MTF2 | metal response element binding transcription factor 2 | -0.0181564 |
| CEP192 | centrosomal protein 192kDa | -0.0181095 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0179008 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0178877 |
| SETD5 | SET domain containing 5 | -0.0178808 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.017809 |
| STX18 | syntaxin 18 | -0.0176438 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0176438 |
| FOXJ3 | forkhead box J3 | -0.0175513 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0175304 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0174728 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0173323 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0173234 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0172857 |
| TNPO3 | transportin 3 | -0.0170001 |
| PGK1 | phosphoglycerate kinase 1 | -0.0169918 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0169872 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0168547 |
