| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.143711 |
| HDAC9 | histone deacetylase 9 | 0.128674 |
| RPS12 | ribosomal protein S12 | 0.123083 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.102892 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.102671 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.082555 |
| NAV2 | neuron navigator 2 | 0.074217 |
| RPL37A | ribosomal protein L37a | 0.0737938 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0623185 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0581445 |
| CD44 | CD44 molecule (Indian blood group) | 0.0579248 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.057531 |
| HLA-B | major histocompatibility complex, class I, B | 0.056535 |
| ATXN1 | ataxin 1 | 0.0544411 |
| RPS6 | ribosomal protein S6 | 0.0528014 |
| SQSTM1 | sequestosome 1 | 0.0507765 |
| B2M | beta-2-microglobulin | 0.0505784 |
| ENO1 | enolase 1, (alpha) | 0.0504567 |
| RPS3 | ribosomal protein S3 | 0.049303 |
| KYNU | kynureninase | 0.0489092 |
| STC1 | stanniocalcin 1 | 0.0473822 |
| NDRG1 | N-myc downstream regulated 1 | 0.0469976 |
| RPS23 | ribosomal protein S23 | 0.0466496 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0442865 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0441449 |
| RPS17 | ribosomal protein S17 | 0.0436984 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0430856 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0423731 |
| LDHA | lactate dehydrogenase A | 0.0423731 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0417538 |
| MX1 | MX dynamin-like GTPase 1 | 0.0416135 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0412047 |
| VCL | vinculin | 0.0404365 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0385657 |
| JMJD1C | jumonji domain containing 1C | 0.0380823 |
| BICC1 | BicC family RNA binding protein 1 | 0.0379173 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0377259 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0375529 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0371858 |
| GOLGB1 | golgin B1 | 0.0370783 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0369788 |
| RPS2 | ribosomal protein S2 | 0.0352401 |
| RPL9 | ribosomal protein L9 | 0.0350401 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0342753 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0332487 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0329368 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0326601 |
| VCAN | versican | 0.0325643 |
| FNIP1 | folliculin interacting protein 1 | 0.0316545 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0314094 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0306497 |
| ARRDC3 | arrestin domain containing 3 | 0.0304188 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0302059 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0301186 |
| RUNX1 | runt-related transcription factor 1 | 0.0301155 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0300622 |
| RPLP2 | ribosomal protein, large, P2 | 0.0299897 |
| RPS8 | ribosomal protein S8 | 0.02966 |
| PLSCR1 | phospholipid scramblase 1 | 0.0291808 |
| CDCP1 | CUB domain containing protein 1 | 0.0288817 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0287168 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0286105 |
| RIGI | RNA sensor RIG-I | 0.0285207 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0283883 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0282889 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0282668 |
| RND3 | Rho family GTPase 3 | 0.0280893 |
| BPTF | bromodomain PHD finger transcription factor | 0.0279994 |
| RPS10 | ribosomal protein S10 | 0.0272992 |
| NAV1 | neuron navigator 1 | 0.0272763 |
| RNF213 | ring finger protein 213 | 0.0271342 |
| MKI67 | marker of proliferation Ki-67 | 0.0265369 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0264906 |
| EXT1 | exostosin glycosyltransferase 1 | 0.026437 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0255765 |
| RPS29 | ribosomal protein S29 | 0.0255157 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0253859 |
| PRELID2 | PRELI domain containing 2 | 0.0250517 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0250241 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0249878 |
| SMYD3 | SET and MYND domain containing 3 | 0.0247473 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0245288 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0243812 |
| RPL26 | ribosomal protein L26 | 0.0242343 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0242093 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0241757 |
| RPS15 | ribosomal protein S15 | 0.0241449 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0241405 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235823 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.023422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0233715 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0233079 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0232512 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231268 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0231255 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0231186 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0231086 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0229132 |
| ASPH | aspartate beta-hydroxylase | 0.0227127 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0225827 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.128641 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107239 |
| PTMA | prothymosin, alpha | -0.102066 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0856482 |
| CADM1 | cell adhesion molecule 1 | -0.0799372 |
| IER3 | immediate early response 3 | -0.0739252 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0685101 |
| PGK1 | phosphoglycerate kinase 1 | -0.0660183 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.065085 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.064899 |
| FTL | ferritin, light polypeptide | -0.0647873 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0610988 |
| ATP13A3 | ATPase type 13A3 | -0.0609325 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0586234 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0584927 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.056991 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0564606 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0559975 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.053926 |
| FRMD4A | FERM domain containing 4A | -0.0537418 |
| RPS24 | ribosomal protein S24 | -0.0517751 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0510955 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0494826 |
| TMSB4X | thymosin beta 4, X-linked | -0.0487063 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0482861 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.047562 |
| QKI | QKI, KH domain containing, RNA binding | -0.0463592 |
| GOLGA4 | golgin A4 | -0.0448682 |
| HELZ | helicase with zinc finger | -0.0448451 |
| RLF | rearranged L-myc fusion | -0.0440844 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0428447 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0426468 |
| GNAS | GNAS complex locus | -0.042523 |
| WTAP | Wilms tumor 1 associated protein | -0.0421555 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0418589 |
| OGA | O-GlcNAcase | -0.0416566 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0394837 |
| SDC4 | syndecan 4 | -0.0390895 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0367094 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0364162 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0361944 |
| TPM4 | tropomyosin 4 | -0.035504 |
| RBM39 | RNA binding motif protein 39 | -0.0353049 |
| COL1A1 | collagen, type I, alpha 1 | -0.0351408 |
| YBX1 | Y box binding protein 1 | -0.034477 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0344595 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0341041 |
| POTEF | POTE ankyrin domain family, member F | -0.0340347 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0336625 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0332914 |
| ZNF292 | zinc finger protein 292 | -0.0332532 |
| TMEM123 | transmembrane protein 123 | -0.0330353 |
| CTSD | cathepsin D | -0.0327217 |
| CAVIN1 | caveolae associated protein 1 | -0.03232 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0322466 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.032164 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0320489 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.031855 |
| SPAG9 | sperm associated antigen 9 | -0.031669 |
| CALR | calreticulin | -0.031304 |
| USP3 | ubiquitin specific peptidase 3 | -0.0312424 |
| CANX | calnexin | -0.0309835 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0306494 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0304632 |
| MATR3 | matrin 3 | -0.0302752 |
| COL1A2 | collagen, type I, alpha 2 | -0.0301368 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0299713 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0297914 |
| TFG | TRK-fused gene | -0.0297842 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0294039 |
| TKT | transketolase | -0.0293394 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.028214 |
| HDLBP | high density lipoprotein binding protein | -0.0278768 |
| WDR45B | WD repeat domain 45B | -0.0277495 |
| ANXA2 | annexin A2 | -0.0277125 |
| RPLP0 | ribosomal protein, large, P0 | -0.0276455 |
| DEK | DEK proto-oncogene | -0.0262617 |
| SRGN | serglycin | -0.0262273 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0260864 |
| CLINT1 | clathrin interactor 1 | -0.0253388 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0252033 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0249196 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0247897 |
| TEX10 | testis expressed 10 | -0.0244498 |
| FAM162A | family with sequence similarity 162, member A | -0.024333 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0242809 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0242684 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0238546 |
| RPS21 | ribosomal protein S21 | -0.0238323 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0238298 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.02382 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0236238 |
| RPLP1 | ribosomal protein, large, P1 | -0.0235064 |
| VIM | vimentin | -0.023487 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0233751 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0233546 |
| SEPTIN7 | septin 7 | -0.0233479 |
| ZNF207 | zinc finger protein 207 | -0.0232667 |
| TMEM263 | transmembrane protein 263 | -0.0227559 |
| UVRAG | UV radiation resistance associated | -0.0227136 |
