| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.164992 |
| SQSTM1 | sequestosome 1 | 0.0792256 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0653947 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0560453 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0410486 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0384778 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0332065 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0331918 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0327254 |
| FMNL2 | formin-like 2 | 0.0305418 |
| SVIL | supervillin | 0.0284723 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0282093 |
| BPTF | bromodomain PHD finger transcription factor | 0.026985 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268426 |
| ENO1 | enolase 1, (alpha) | 0.0268003 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0267211 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0266014 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0257681 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0257326 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0255757 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0255199 |
| B2M | beta-2-microglobulin | 0.0236406 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228347 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0226294 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0224147 |
| RPL35A | ribosomal protein L35a | 0.0222992 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0219602 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0216635 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0215568 |
| PHF20 | PHD finger protein 20 | 0.0214494 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.02046 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0204081 |
| LRRC49 | leucine rich repeat containing 49 | 0.0200906 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.019926 |
| RPS8 | ribosomal protein S8 | 0.0197921 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0197607 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0196941 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0195573 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0195307 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0190537 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.019053 |
| CENPP | centromere protein P | 0.0190362 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0189436 |
| GPATCH8 | G patch domain containing 8 | 0.0187511 |
| INTS6 | integrator complex subunit 6 | 0.0182193 |
| AHR | aryl hydrocarbon receptor | 0.0176872 |
| LUZP1 | leucine zipper protein 1 | 0.0174142 |
| R3HDM2 | R3H domain containing 2 | 0.0172479 |
| SIK2 | salt-inducible kinase 2 | 0.0171634 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0169984 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0169546 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0168481 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0166284 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0164989 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0163872 |
| RPS12 | ribosomal protein S12 | 0.0163299 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0161703 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0158946 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0158773 |
| TNPO1 | transportin 1 | 0.0158222 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0157975 |
| PRKCA | protein kinase C, alpha | 0.0157741 |
| JAK1 | Janus kinase 1 | 0.0157164 |
| PRR16 | proline rich 16 | 0.0155879 |
| FTL | ferritin, light polypeptide | 0.0155729 |
| FNIP1 | folliculin interacting protein 1 | 0.0155664 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0154886 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0154474 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0153995 |
| MED13L | mediator complex subunit 13-like | 0.0153193 |
| RPS13 | ribosomal protein S13 | 0.0151929 |
| ZXDC | ZXD family zinc finger C | 0.0151148 |
| GPC5 | glypican 5 | 0.0151026 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0150999 |
| RPS27A | ribosomal protein S27a | 0.0150904 |
| SH3D19 | SH3 domain containing 19 | 0.0150216 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0150164 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0149541 |
| NBEA | neurobeachin | 0.0147762 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0147672 |
| TLE4 | transducin-like enhancer of split 4 | 0.0146692 |
| AOPEP | aminopeptidase O (putative) | 0.0144714 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0144357 |
| UBQLN1 | ubiquilin 1 | 0.014286 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0141951 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0141849 |
| PSEN1 | presenilin 1 | 0.0140897 |
| CUX1 | cut-like homeobox 1 | 0.0140873 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0140245 |
| RPS25 | ribosomal protein S25 | 0.0139806 |
| TCF12 | transcription factor 12 | 0.0138094 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0137478 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0137114 |
| DENND5B | DENN/MADD domain containing 5B | 0.0136377 |
| SET | SET nuclear proto-oncogene | 0.0134655 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0134595 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0132958 |
| TXNIP | thioredoxin interacting protein | 0.0132567 |
| SMIM14 | small integral membrane protein 14 | 0.0132174 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0131645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0637966 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0524486 |
| VIM | vimentin | -0.0515328 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0504598 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0397791 |
| PRELID2 | PRELI domain containing 2 | -0.038697 |
| FLNB | filamin B, beta | -0.0384452 |
| AHNAK | AHNAK nucleoprotein | -0.0356204 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0351585 |
| YAP1 | Yes-associated protein 1 | -0.0327303 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0311245 |
| PFN1 | profilin 1 | -0.0309137 |
| GOLGA4 | golgin A4 | -0.0300823 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.029714 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0294569 |
| MT2A | metallothionein 2A | -0.0290894 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0284333 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0282734 |
| DTNA | dystrobrevin, alpha | -0.0280631 |
| LAMA5 | laminin, alpha 5 | -0.0279828 |
| PTMA | prothymosin, alpha | -0.0266164 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0265851 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0255881 |
| MSN | moesin | -0.0255417 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0254476 |
| RAD51B | RAD51 paralog B | -0.0251308 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.025102 |
| PTK2 | protein tyrosine kinase 2 | -0.0249613 |
| RAI14 | retinoic acid induced 14 | -0.0244488 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0238731 |
| EGR1 | early growth response 1 | -0.0238052 |
| NBAS | neuroblastoma amplified sequence | -0.0234564 |
| NAV2 | neuron navigator 2 | -0.0234251 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0230176 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.02299 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0227468 |
| CEP250 | centrosomal protein 250kDa | -0.0225329 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0220938 |
| SEPTIN7 | septin 7 | -0.0218963 |
| SCFD1 | sec1 family domain containing 1 | -0.0216644 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0216473 |
| ASPH | aspartate beta-hydroxylase | -0.0213887 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0212639 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0212248 |
| SNX14 | sorting nexin 14 | -0.020834 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0204862 |
| NDRG1 | N-myc downstream regulated 1 | -0.0201924 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0201621 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0200176 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.019842 |
| POTEF | POTE ankyrin domain family, member F | -0.0198369 |
| HDLBP | high density lipoprotein binding protein | -0.0197557 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0196761 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0196625 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0196263 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0194567 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0194002 |
| COL5A1 | collagen, type V, alpha 1 | -0.0193806 |
| SEPTIN2 | septin 2 | -0.0193241 |
| RBM39 | RNA binding motif protein 39 | -0.0192156 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0190807 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0187361 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0186703 |
| FAM13B | family with sequence similarity 13, member B | -0.0186502 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0185872 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0185595 |
| WASF2 | WAS protein family, member 2 | -0.0185532 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0183838 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0183828 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0183687 |
| TPX2 | TPX2, microtubule-associated | -0.0183446 |
| ATP13A3 | ATPase type 13A3 | -0.0182902 |
| SEC24A | SEC24 family member A | -0.0182446 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.018013 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0179647 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0179499 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0177928 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0177059 |
| HMGA2 | high mobility group AT-hook 2 | -0.0175259 |
| RBM25 | RNA binding motif protein 25 | -0.0173838 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0172529 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0172316 |
| IDS | iduronate 2-sulfatase | -0.0171696 |
| TGM2 | transglutaminase 2 | -0.0171665 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0171469 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0168945 |
| CRLS1 | cardiolipin synthase 1 | -0.0168807 |
| CALU | calumenin | -0.0168575 |
| GLG1 | golgi glycoprotein 1 | -0.016853 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0165696 |
| ACTN1 | actinin, alpha 1 | -0.0165569 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0165376 |
| ZNF292 | zinc finger protein 292 | -0.0164266 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0162808 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0161597 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0161539 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0160945 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0160645 |
| PGK1 | phosphoglycerate kinase 1 | -0.0160596 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0159978 |
